KD, knockdown
Pancreas enriched miRNA refines endocrine cell differentiation
... miR-7 knockdown, relative to negative control scrambled oligo (‘miR-7 KD’, ‘Ctrl KD’, ...miR-7 KD with siPax6 restores insulin promoter activity (right ...
11
Quantitative hormone therapy follow-up in an ER+/ERαKD mouse tumor model using FDG and [11C]-methionine PET imaging
... A new model of MC7-L1 ER α -knockdown (ER α KD) tumor cell lines was designed as a negative estrogen receptor control to follow up the effects of changes in ER α expression on the early [r] ...
10
Dopamine D3 receptor and GSK3β signaling mediate deficits in novel object recognition memory within dopamine transporter knockdown mice
... DAT-KD mice during training and consequent impair- ment of NOR task performance. Surprisingly, phosphor- ylation of ERK1/2 in the PFC was previously reported to be increased after 10 min of novelty exposure [29, ...
12
Deptor Knockdown Enhances mTOR Activity and Protein Synthesis in Myocytes and Ameliorates Disuse Muscle Atrophy
... Deptor knockdown (KD) using short hairpin (sh)-RNA–based in vitro experimental ...Deptor KD by electroporation could ameliorate the decrease in muscle mass and protein synthesis seen in a catabolic ...
12
Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells
... PTK7 knockdown cells, PTK7-KD-6433 and PTK7-KD-6434, showed significantly decreased degradation of FITC- labeled gelatin compared to control vector-transfected cells (Figure ...PTK7 knockdown ...
15
MicroRNA-214-3p inhibits the stem-like properties of lung squamous cell cancer by targeting YAP1
... algorithms such as miRanda and TargetScan recom- mended that YAP1 possesses potential complementary sites for the miR-214-3p seed region in the 3 ′ Untrans- lated Region (3 ′ UTR) (Fig. 5a). To verify this hypothesis, we ...
13
Suppression of APC/C Cdh1 has subtype specific biological effects in acute myeloid leukemia
... progression, development and differentiation in many cell types. However, little is known about the role of Cdh1 in hematopoiesis. Here we analyzed Cdh1 expression and function in malignant hematopoiesis. We found a ...
11
Splicing factor SRSF1 promotes gliomagenesis via oncogenic splice switching of MYO1B
... SRSF1 knockdown (Figure 5A, primer set ...SRSF1 knockdown significantly result- ed in skipping of the 2 adjacent exons and facilitated the expression of the truncated MYO1B isoform in the KD sub–cell ...
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Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells
... To further evaluate the role of Gas5 during mESC differ- entiation, we first examined the effect of Gas5 on mESC differentiation using an in vitro differentiation model. Differentiation was observed as early as day 5 in ...
13
Evidence of multiple insecticide resistance mechanisms in Anopheles gambiae populations in Bangui, Central African Republic
... Non blood-fed, 2–3-day-old female A. gambiae mosqui- toes grown from collected larvae were used for insecti- cide susceptibility tests. Bioassays were carried out using WHO test kits for adults mosquitoes [19], to assess ...
10
Neurogenesis in the sea urchin embryo is initiated uniquely in three domains
... (C) Knockdown (KD) of delta expression causes each of the proneural transcription factor genes to be expressed in an increased number of cells relative to controls at the same stage in the territories where ...
12
GEP, a Local Growth Factor, is Critical for Odontogenesis and Amelogenesis
... Our quantitative analysis showed a significant difference in the thickness of dentin and predentin between the WT and the GEP KD mice. The ratio of dentin to predentin also decreased sharply from the GEP KD ...
11
RKIP reduction enhances radioresistance by activating the Shh signaling pathway in non-small-cell lung cancer
... To explore the effect of RKIP reduction on the radiore- sistance of NSCLC cells, we regulated RKIP expression by stably transfecting an antisense RKIP short hairpin RNA (shRNA) expression lentivirus into the human lung ...
15
The mineralocorticoid receptor contributes to barrier function of a model fish gill epithelium
... Previous studies have reported that cortisol-induced tightening of the gill epithelium is relayed though both the GR and MR, but these studies were conducted using pharmacological agents that arguably lack specificity or ...
12
Prokop, Stefan (2006): Funktionelle Charakterisierung der gamma-Sekretasekomponente PEN-2. Dissertation, LMU München: Medizinische Fakultät
... PEN-2 knockdown cells ...PEN-2 knockdown cells were slightly increased indicating degradation of excess free amounts ...the knockdown cells were unchanged upon clasto-lactacystin -lactone treatment ...
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Kikuchi's Disease in Asian Children
... years (mean: 12.8 years), with 2 children younger than 10 years. A total of 189 cervical lymph biopsies were performed on children at our hospital during the study period, so KD accounted for 12.2% (23 of 189) of ...
7
Safe and easy hair transplantation utilizing KD spreader
... The upper surface of the KD spreader has a shielded magnet that allows for attachment and detachment of the plates [Figure 4]. This device has another unique feature: at the time of implantation, it provides an ...
7
Dettmer, Ulf (2010): Identification of the transmembrane protein 147 (TMEM147) as a novel component of the Nicalin-NOMO membrane protein complex. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... TMEM147 knockdown cell lines was developed (1) to analyze the universality of the effects of Nicalin and NOMO downregulation and (2) to examine the consequences of TMEM147 ...
100
Knockdown Arguments
... baculum fallacy independently of the other elements. And the third factor is built on top of the second: threats aren't good reasons in the type of dialogue that the sales[r] ...
21
Text ABSTRACT (ABSTRAK) pdf
... masalah Siswa mendiskusikan alternatif pemecahan masalah Materi pembelajaran dalam LKPD mengacu/ sesuai KD 1 Tujuan pembelajaran sesuai KD 2 Materi pembelajaran sesuai KD 3 Kegiatan dala[r] ...
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