Keratinocyte growth-factor
Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo
... Keratinocyte growth factor (KGF) administered as a single intratracheal injection causes a prominent dose-dependent proliferation of type II alveolar epithelial cells in the lungs of adult ...
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Keratinocyte growth factor impairs human thymic recovery from lymphopenia
... Keratinocyte growth factor (KGF) promotes thymopoiesis through its trophic effects on thymic epi- thelial cells ...essential growth factors and presenting self-antigen to developing ...
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Original Article Therapeutic effects of recombinant human keratinocyte growth factor-2 on hyperoxia-induced bronchopulmonary dysplasia in neonatal rats
... Abstract: Background: Bronchopulmonary dysplasia (BPD) is one of the most devastating conditions in premature babies; meanwhile, keratinocyte growth factor-2 (KGF-2) plays a key role in lung ...
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Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo controlled trial (KARE): study protocol
... of keratinocyte growth factor for patients with acute lung injury on oxygenation and biological indicators of acute inflammation, lung epithelial and endothelial function, protease:antiprotease ...
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Original Article Keratinocyte growth factor up-regulates Interleukin-7 expression following intestinal ischemia/reperfusion in vitro and in vivo
... Abstract: Background: Epithelial cell (EC)-derived Interleukin-7 (IL-7) plays a crucial role in control of neighboring intestinal intraepithelial lymphocytes (IEL) development and homeostasis, and IEL derived ...
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A Plasmid vector encoding functional human keratinocyte growth factor gene in vitro—Functional human KGF gene expression in vitro
... Keratinocyte growth factor (KGF; also known as FGF-7), a member of the FGF family, is a potent mito- gen specific for epithelial cells ...epithelial growth as a stromal-derived paracrine regu- ...
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Original Article Glucocorticoids restrain bronchial epithelial wound repair by decreasing fibroblasts keratinocyte growth factor expression
... [6]. Keratinocyte growth factor (KGF), a member of the fibroblast growth factor (FGF) family, is a typical paracrine acting growth ...
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Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate
... Int J Dev BioI 40 941 951 (1996) 941 Original Article Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate YOSHIKI SUGIMURA', BAR[.] ...
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Original Article Expression of keratinocyte growth factor and its receptor in oral lichen planus
... Abstract: This study aimed to investigate the expression of keratinocyte growth factor (KGF) and its receptor KGFR in oral lichen planus (OLP). Oral mucosa specimens from 30 OLP patients and ten ...
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Proliferation induced by keratinocyte growth factor enhances in vivo retroviral mediated gene transfer to mouse hepatocytes
... combining growth factor pretreat- ment with high titer retroviral ...polypeptide growth factors including EGF, hepatocyte growth factor, and acidic fibroblast growth ...
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Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin binding growth factors for alveolar type II cells in fibroblast conditioned medium
... fibroblast growth factor, epidermal growth factor, and ...The growth factor activity bound to heparin-Sepharose and was eluted with ...were keratinocyte growth ...
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The role of keratinocyte growth factor and receptor in gingival hyperplasia
... In the GH tissue sections, the diffuse appearance of KGF in CT with no clear association with a particular cell type, might reflect the binding of KGF to HSPG, which are low- affinity non-signalling receptors and have ...
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Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract
... Therefore, rKGF was administered to adult rats and was found to induce markedly increased proliferation of epithelial cells from the foregut to the colon, and of hepatocytes, one day aft[r] ...
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Interactions between stromal cell derived keratinocyte growth factor and epithelial transforming growth factor in immune mediated crypt cell hyperplasia
... the growth factor (0–20 ng/ml) to the explant culture system had no effect on epithelial cell proliferation; however, at higher doses (500 ng/ml) either KGF or TGF- a caused a twofold increase in epithelial ...
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Efficacy of palifermin (keratinocyte growth factor-1) in the amelioration of oral mucositis
... Assuming proof of efficacy, two barriers might impede the adoption of palifermin in this group: 1. palifermin is relatively expensive and cost-benefit will have to be demonstrated, especially in nonhead and neck cancer ...
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Intratracheal instillation of keratinocyte growth factor decreases hyperoxia induced mortality in rats
... To determine the effect of administration of 5 mg/kg rhKGF on hyperoxia-induced lung injury, rats were treated by intratracheal instillation and exposed to hyperoxia for up to 120 h.. At[r] ...
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Modulation of Wnt/β-catenin signaling affects the directional differentiation of hair follicle stem cells
... Figure 8: Effect of different keratinocyte growth factor (KGF) concentrations on hair follicle stem cells proliferation. Cells were assessed 3 days after treatment. (A) the KGF 0 µg/L group shows ...
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Mesenchymal stem cells-derived extracellular vesicles in acute respiratory distress syndrome: a review of current literature and potential future treatment options
... increasing keratinocyte growth factor (KGF), overexpression of angiopoietin-1, reprogramming of macrophage function and secretion of antimicrobial peptides [28, 32, ...
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Palifermin for management of treatment-induced oral mucositis in cancer patients
... over US$40,000 per patient affl icted by ulcerative lesions, based on Medicare reimbursement rates. Thus, therapy- induced OM is far from trivial and recent efforts have been directed at fi nding prophylactic and ...
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Field cancerisation in colorectal cancer
... tumour growth facilitating both invasion and metastasis (O'Toole et ...fibroblast growth factor 7 (FGF7) as being dysregulated in the MNM adjacent to polyps compared to MNM taken from control ...as ...
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