Ketorolac tromethamine
Development and validation of a headspace gas chromatographic method for the determination of ethyl alcohol in ketorolac tromethamine injection
... The developed GC–Head space method was found to be precise, linear, specific, robust and accurate for the determination of ethyl alcohol content in Ketorolac Tromethamine injection. Hence the validated ...
8
Formulation Development and Evaluation of Ketorolac Tromethamine Gel for Topical Application in Pain Management
... To find the drug content uniformity of ketorolac tromethamine in gel, spectrophotometric method was followed.1 gm of gel was transferred to a 100 ml volumetric flask, 70 ml of phosphate buffer pH 7.4 was ...
6
DEVELOPMENT AND EVALUATION OF ORAL COLON TARGETED KETOROLAC TROMETHAMINE CAPSULE
... Ketorolac tromethamine was selected as a model drug because it belongs from NSAID’s category which used for anti-inflammatory and analgesic effect, as equal potent to opoid analgesic (morphin) and used for ...
7
SIMULTANEOUS DETERMINATION OF KETOROLAC TROMETHAMINE AND OLOPATADINE-HCl IN PURE FORM, MARKETED TABLETS AND NEW FORMULATED FAST DISSOLVING FILMS
... Ketorolac, was kindly supplied by Amriya Pharmaceutical Co (Egypt), its purity was 99.77% as stated by the supplier. Olopatadine HCl, was kindly supplied by Egyptian International Pharmaceutical Co. (EIPICO, ...
25
IN VITRO RELEASE CHARACTERIZATION OF KETOROLAC TROMETHAMINE LOADED MATRIX TABLETS
... INTRODUCTION: Ketorolac Tromethamine is a novel Non-steroidal anti-inflammatory drug (NSAID) with potent analgesic & modest anti-inflammatory ...
8
Chitosan Loaded Ketorolac Tromethamine Nanoparticles for Improved Ocular Delivery in Eye Inflammation
... Aim: Ketorolac tromethamine (KT) is highly effective in treating post-operative eye inflammation, allergic conjunctivitis as well other ...of Ketorolac tromethamine were prepared by ionotropic ...
8
Treatment of Retinopathy of Prematurity with topical ketorolac tromethamine: a preliminary study
... which ketorolac tromethamine was used, when risk signs for ROP were identified (zone I incomplete vascularization, vessels only in zone of transi- tion I-II or anomalous ramification and equatorial incur- ...
6
Formulation, Development and Evaluation of Ketorolac Tromethamine Film Coated Tablets
... intranasal ketorolac tromethamine (ketorolac) for postoperative ...intranasal ketorolac, 10 mg or 30 mg, or placebo every 8 h for 40 ...10-mg ketorolac group ...
91
METHOD DEVELOPMENT AND VALIDATION OF KETOROLAC TROMETHAMINE IN TABLET FORMULATION BY RP HPLC METHOD
... ABSTRACT: In the present study, a simple, precise, and accurate method was developed and validated for analysis of Ketorolac Tromethamine in Tablet formulation. A gradient HPLC analysis was performed on ...
8
Entrapment of ketorolac tromethamine in polymeric vehicle for controlled drug delivery
... The most common method for applying a drug in to the eye is to formulate the drug in the form of an eye drop, but this method is not considered ideal for ocular delivery of drug because of poor bioavailability arising ...
5
DEVELOPMENT AND VALIDATION OF A STABILITY INDICATING RP-HPLC METHOD FOR THE ESTIMATION OF KETOROLAC TROMETHAMINE IN DRUG SUBSTANCE AND ITS PHARMACEUTICAL FORMULATIONSSrinivas Ganta*, Dr. S. Vidyadhara, Ramanaiah Ganji and Srilakshmi. VDOWNLOAD/VIEW
... of Ketorolac tromethamine into a 100 ml volumetric flask add about 70 ml of diluent, and sonicate for 30minutes with intermittent shaking at controlled ...
10
Development and validation of HPTLC method for the simultaneous analysis of gatifloxacin and ketorolac tromethamine in eye drops
... is Ketorolac Tromethamine. Ketorolac Tromethamine (KETO) is chemically, 5-Benzoyl-2,3 -Dihydro-1H-Pyrolizine-1-Carboxylic Acid,2 Amino-2-(hydroxymethyl)-1,3- Propaneddiol ...
7
FORMULATION AND OPTIMIZATION OF KETOROLAC TROMETHAMINE HCl FAST DISINTEGRATING TABLETS BY EXPERIMENTAL DESIGN
... of Ketorolac tromethamine HCl minimized by formulating Ketorolac tromethamine HCl fast disintegrating tablets using natural super ...of Ketorolac tromethamine HCl fast ...
8
Formulation and pharmacopoeial quality evaluation of ketorolac tromethamine IR tablet and comparison with marketed product
... Ketorolac tromethamine is a non-steroidal anti- inflammatory drug having potent analgesic activity chemically which is 2-amino-2-(hydroxymethyl) propane-1,3-diol; 5-benzoyl- ...
6
Novacap technique for pulsatile drug delivery of ketorolac tromethamine microspheres
... The multi-phase multi-compartment capsule based combination pulsatile delivery system was developed which consist of four parts i.e. fast dissolving tablet of Ketorolac Tromethamine, Microspheres of ...
11
Design and evaluation of ph triggered in situ ophthalmic gel of moxifloxacin hydrochloride and ketorolac tromethamine combination
... and Ketorolac tromethamine combination are prepared by using carbopol 934 as gelling agent and carboxy methyl tamarind kernel powder and Hydroxy propyl methyl cellulose K15M as viscosity enhancing agent and ...
8
DESIGN, AND EVALUATION OF OCULAR INSERTS FOR CONTROLLED DRUG DELIVERY OF KETOROLAC TROMETHAMINE
... [8] Ketorolac tromethamine (KTM) is a potent, non-narcotic, non-steroidal analgesic with moderate anti-inflammatory activity and is used in the management of seasonal allergic conjunctivitis, postoperative ...
13
Evaluation of analgesic efficacy of bromfenac sodium ophthalmic solution 0.09% versus ketorolac tromethamine ophthalmic solution 0.5% following LASEK or Epi-LASIK
... This study was a prospective, randomized, single-center study. All surgeries were performed by one surgeon (EWC). An independent investigational review board (IRB Inc, Plantation, FL) approved the project, and informed ...
7
FORMULATION AND EVALUATION OF BUCCAL FILMS OF KETOROLAC TROMETHAMINE
... of Ketorolac from the patches were diffusion rate ...of Ketorolac tromethamine and will provide an improved therapeutic efficacy and patient ...
9
DESIGN, DEVELOPMENT AND CHARACTERIZATION OF KETOROLAC TROMETHAMINE NANOSUSPENSION LOADED IN SITU MUCOADHESIVE OCULAR GEL
... that, ketorolac tromethamine nanosuspension loaded in situ gel will be the efficient ocular drug delivery system for the treatment of postoperative inflammation through improved patient compliance and ...
7