Kidney Injury Molecule 1:
The Accuracy of Kidney Injury Molecule- 1 for Earlier Diagnosis Acute Kidney Injury in Polytrauma
... Kidney injury molecule-1 is a type 1 transmembrane glycoprotein that has an extracellular domain and cytoplasmic ...after kidney damage due to ischemic or toxin. The advantages ...
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Urinary Kidney Injury Molecule-1 (KIM-1) in Early Diagnosis of Acute Kidney Injury in Pediatric Critically Ill
... Acute kidney injury (AKI) often associated with a high hospital morbi-mortality rate in the intensive care unit pa- ...tients. Kidney injury molecule-1 (KIM-1), has many ...
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Chronic epithelial kidney injury molecule 1 expression causes murine kidney fibrosis
... Acute kidney injury predisposes patients to the development of both chronic kidney disease and end-stage renal failure, but the molecular details underlying this important clinical association remain ...
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Kidney injury molecule-1 expression in human kidney transplants with interstitial fibrosis and tubular atrophy
... Real-time polymerase chain reaction (RT-PCR) was performed in the cDNA from tissue and urine samples by using the TaqMan Universal PCR Master Mix, composed by AmpliTaq Gold® DNA polymerase, Amperase UNG, passive ...
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Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells
... Following injury, the clearance of apoptotic and necrotic cells is necessary for mitigation and resolution of inflammation and tissue ...process. Kidney injury molecule–1 (KIM-1 ...
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Assessment of urinary kidney injury molecule-1 and interleukin-18 in the early post-burn period to predict acute kidney injury for various degrees of burn injury
... the Kidney Disease Improving Global Outcomes (KDIGO) 2012 AKI guidelines, AKI is de- fined as an increase in Scr to ...early kidney injury that are sensitive, specific, and ...as kidney ...
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Original Article Increased expression of kidney injury molecule-1 and matrix metalloproteinase-3 in severe Plasmodium falciparum malaria with acute kidney injury
... July 1, 2017; Published July 15, 2017 Abstract: Kidney injury molecule-1 (KIM-1) is a specific histological biomarker for diagnosing early acute kidney injury which ...
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KIDNEY INJURY MOLECULE 1 (KIM-1) AND THE LOSS OF KIDNEY FUNCTION IN DIABETIC NEPHROPATHY: A LIKELY CAUSAL LINK IN PATIENTS WITH TYPE 1 DIABETES
... KIM-1 – univariate analysis for KIM-1; AER – univariate analysis for AER; KIM-1 & AER – Cox regression model with KIM-1 plus AER in the model without any correction; eGFR– univariate ...
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Evaluation of Adrimycin and Cyclophosphamide Nephrotoxicity Using Urinary Kidney Injury Molecule -1 In Brest Cancer Patients
... for Kidney Function Blood and urine samples were collected 24 hours before chemotherapy and 24 hours after ...and Kidney Injury Molecule-1 ...
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Review Article Accuracy of urinary kidney injury molecule-1 in predicting acute kidney injuries associated with cardiac surgery: a systematic review and meta-analysis
... Urinary kidney injury molecule-1 (uKIM-1) is a very promising diagnostic biomarker for acute kidney injuries (AKI), but its accuracy has varied widely in different ...
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Kidney Injury Molecule-1 Signalling in Ischemic Acute Kidney Injury and Phagocytosis
... 147 4.1. SUMMARY In this chapter, we identify and study another novel KIM-1-interacting protein. Using a yeast two-hybrid system, we describe the identification of the 14-kDa light chain of cytoplasmic dynein ...
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Study of urinary level of kidney injury molecule-1 (KIM-1) in acute kidney injury.
... volume. 1 AKI is a new consensus term encompassing a spectrum of kidney disease of acute onset, which may range in severity from asymptomatic changes in the laboratory parameters of glomerular filtration ...
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Effect of treatment on urinary kidney injury molecule-1 in IgA nephropathy
... For the present study, prospective patients with biopsy- proven IgAN were enrolled from January 2009 at Soon Chun Hyang University Seoul and Bucheon Hospital. Study protocols were reviewed and approved by the Soon Chun ...
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The role of kidney injury molecule-1 in the metastasis of renal cell carcinoma
... KIM- 1 actively cleaved by MT1-MMP, which resulted in significantly increased cell adhesion, invasive growth, and metastasis compared with HT1080/ΔKIM-1 ...
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Mapping and functional characterization of proteolytic cleavage of murine kidney injury molecule-1
... Next, I would like to thank the other pivotal members of my lab family. Dr. Xizhong Zhang, Dr. Elena Tutunea-Fatan, and Brad Shrum have been guiding and teaching me many of the lab techniques that I have learned during ...
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High urinary excretion of kidney injury molecule 1 predicts adverse outcomes in acute kidney injury: a case control study
... Statistical analysis SPSS13.0 statistical software IBM (NY, USA) was used. Normally distributed measurement data are expressed as mean ± sd, and the t test was used for group compari- sons. Measurement data with a ...
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Kidney Injury Molecule-1 Protects against Gα12 Activation and Tissue Damage in Renal Ischemia-Reperfusion Injury
... Discussion AKI is a serious medical condition with no known treatment and unresolved pathogenic mechanisms. It was recently discovered that Ga12 has a crucial pathogenic role in renal IRI. 9,15 Speci fically, ROS ...
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Urinary kidney injury molecule-1 and monocyte chemotactic protein-1 are noninvasive biomarkers of cisplatin-induced nephrotoxicity in lung cancer patients.
... β-D-glucosaminidase (NAG) (d), and β2-microglobulin (e) in acute kidney injury (AKI) positive (+) and AKI negative ( −) samples from lung cancer patients treated with cisplatin. Statist[r] ...
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Urinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria
... Fifty-one patients, aged >14 years, with renal-biopsy- proven IgAN, from Tianjin Medical University General Hospital between October 2011 and November 2013 were enrolled. Normotension was defined as systolic blood ...
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The association between urinary kidney injury molecule 1 and urinary cadmium in elderly during long-term, low-dose cadmium exposure: a pilot study
... letter. Of those that routinely are advised for influenza vaccination, approximately 86% joined the vaccination program. Of those that were eligible, 154 were recruited, and 99% agreed to participate in our study. Of the ...
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