Label-Free
Label-free quantitative phosphorylation analysis of human transgelin2 in Jurkat T cells reveals distinct phosphorylation patterns under PKA and PKC activation conditions
... protein label-free phosphorylation quantita- tive analysis revealed distinct phosphorylation changes of transgelin2 in Jurkat T cell lines under the PKC and PKA activation conditions, which are comparable ...
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Label-free affinity biosensor arrays : novel technology for molecular diagnostics
... home. Label-free affinity biosensors are an emerging technology with the potential to meet these requirements and significant progress has been made, especially by exploiting the technological advances of ...
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A label-free quantitative shotgun proteomics analysis of rice grain development
... With advances in mass spectrometry, multidimen- sional protein identification technology (MudPIT), a shotgun proteomic approach, was developed for large- scale, high-throughput protein identification [8]. The benefits of ...
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Glycosylated gold nanoparticle libraries for label free multiplexed lectin biosensing
... Herein, we describe a polymer-stabilised, glycosylated gold nanoparticle platform for the high-throughput and importantly label-free screening of carbohydrate–lectin interactions and demonstrate its ...
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Label free optical hemogram of granulocytes enhanced by artificial neural networks
... In conclusion, this study has used multivariate analysis based approaches for label free hemograms using either WMR spectra or phase images obtained using digital holographic microscopy from two cell lines. ...
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Label-free photonics biosensor transducing nano-biological events
... and label-free detection system, it is generally accepted that molecular interactions with label probes are involving non-native interactions, and could possibly leads to false information ...
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Flexible Label-Free Quantitative Assay for Antibodies to Influenza Virus Hemagglutinins
... flexible label-free and cell-free assay to determine the relative functional avidity of polyclonal serum antibodies binding to the major virion coat protein, ...with label-free biolayer ...
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Optimal design of label free silicon “lab on a chip” biosensors
... Opto-fluidic label free “lab on a chip” arrayed biosensors are currently a major interdisciplinary research topic. Research breakthroughs in this area will bring about new generations of biosensing ...
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Label-Free Electrochemical Sensor for MicroRNAs Detection with Ferroceneboronic Acids as Redox Probes
... the 3′-end of miRNAs can be selectively modified by Os(VI)2,2′-bipyridine [20]. Rahman et al. reviewed the advances in the development of particle-based nucleic acid purification and detection in view of the difference ...
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Label-free integrative pharmacology on-target of opioid ligands at the opioid receptor family
... developed label-free integrative pharmacology on-target (iPOT) approach to systematically survey the selectivity of a library of fifty-five opioid ligands against the opioid receptor ...
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Rapid label free identification of mixed bacterial infections by surface plasmon resonance
... clinical practice. Firstly, it has the capability of real- time monitoring, which is a crucial characteristic of biosensors and also reduces the detection time. Once the refractive index changes when the DNA-DNA ...
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Label free Raman hyperspectral imaging of single cells cultured on polymer substrates
... While Raman hyperspectral imaging has been widely used for label-free mapping of biomolecules in cells, these measure- ments require the cells to be cultured on weakly Raman scattering substrates. However, ...
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“RECENT ADVANCES IN LABEL FREE TECHNOLOGIES IN DRUG DISCOVERY AND DEVELOPMENT” by T. M. Kalyankar, Khadkutkar P.K, Chevale S.L, India. Digital copy link
... By means of assay with high density formats by using the primary cells or stem cells may be limited until new methods have been developed to the decrease cell numbers. SRU Biosystems has launched an image reader which is ...
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Label-Free Luminescent Mesoporous Silica Nanoparticles for Imaging and Drug Delivery
... We report herein a straightforward and label-free approach to prepare luminescent mesoporous silica nanoparticles. We found that calcination at 400 °C can grant mesoporous organosilica na- noparticles with ...
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Label-Free Electrochemical Sensing Platform for the Detection of Protease
... limit was estimated to be 0.5 ng mL -1 , which is comparable to that achievable using Fc-labeled peptide probe [20]. A point worth to mention is that Fc-labeled sensor exhibits a significant signal loss after multiple ...
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Label-free and washing-free alkaline phosphatase assay using a personal glucose meter
... We herein developed a PGM-based method for a label-free and washing-free ALP assay. This strategy relies on the working principle that ALP, which scav- enges on ATP and suppresses the subsequent ...
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Antibody mimetic receptor proteins for label-free biosensors
... A label-free electrochemical sensor was fabricated by functionalising a microfabricated gold electrode with the receptor ...in label-free ...
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Silicon Photonic Biosensors Using Label-Free Detection
... Abstract: Thanks to advanced semiconductor microfabrication technology, chip-scale integration and miniaturization of lab-on-a-chip components, silicon-based optical biosensors have made significant progress for the ...
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Label-free Detection of Single Molecule Using Microtoroid Optical Resonators
... used label-free tests is, the ELISA, which senses an analyte via its binding to an ...sensitive label- free techniques, resulting in a range of new ultra-sensitive techniques including optical ...
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Laser Optical Sensor, a Label Free On Plate Salmonella enterica Colony Detection Tool
... Laser Optical Sensor, a Label Free On Plate Salmonella enterica Colony Detection Tool Laser Optical Sensor, a Label Free On Plate Salmonella enterica Colony Detection Tool Atul K Singh,a Amanda M Bett[.] ...
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