Laminin binding
Exogenous expression of the glycosyltransferase LARGE1 restores α-dystroglycan matriglycan and laminin binding in rhabdomyosarcoma
... The first sample-set tested was the Children’s Oncol- ogy Group Lookback tissue microarray (P1542), which includes both aRMS and eRMS subtypes. Nearly all eRMS and aRMS samples that were examined were negative for IIH6 ...
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Co expression of laminin and a 67 kDa laminin binding protein in teratocarcinoma embryoid bodies
... Int J De, Hiol 38 ]2] 126 (1994) 121 Short Contribution Co expression of laminin and a 67 kDa laminin binding protein in teratocarcinoma embryoid bodies I FERNANDO J UNDA*, MANUEL GARCIA SANZ, RAFAEL[.] ...
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The 67 kD elastin/laminin binding protein is related to an enzymatically inactive, alternatively spliced form of beta galactosidase
... and laminin and for mediating the process of elastin fiber assembly, but the nature of this protein was ...and laminin, but not to fibronectin, collagen I, or collagen ...and laminin which bind to ...
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Adhesion of B16 malignant melanoma cells to the endothelium and to subendothelia matrix components
... some binding to immobilized fibronectin and collagen type I or ...for laminin comparable to that exhibited by whole cells (von der Mark and Kuhl, 1985; Ekblom et a l ...matrix laminin and the ...
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An adhesome comprising laminin, dystroglycan and myosin IIA is required during notochord development in Xenopus laevis
... of laminin binding to the cell surface, leading to the breakdown of notochord; an impairment of cell polarity leading to disruption of mediolateral intercalation; and a deficiency in vacuole formation, ...
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A putative receptor for Venezuelan equine encephalitis virus from mosquito cells.
... of laminin-binding proteins as receptors for virus attachment by VEE virus appears to provide a plausible explanation for the observed broad host range of this ...virus. Laminin-binding pro- ...
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Identification of dystroglycan as a second laminin receptor in oligodendrocytes, with a role in myelination
... with laminin extracellular ...the laminin ligand (reviewed in Feltri and Wrabetz, 2005; Jimenez-Mallebrera et ...nerves, laminin removal causes a severe combination of amyelination and ...
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Whole Genome Sequencing of Invasion Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion
... (18). Laminin subunit ␣ 2 is found as part of laminin-211 (laminin- ␣ 2  1 ␥ 1), laminin-221 (laminin- ␣ 2  2 ␥ 1), and the less-abundant laminin-213 (laminin- ␣ 2  1 ␥ ...
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Prenatal muscle development in a mouse model for the secondary dystroglycanopathies
... are not associated with an overt muscle pathology at birth [32], we further hypothesized that the initial diver- gence between FKRP KD and wild type would take place during the later stages of muscle development. An ...
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Basal cell adhesion molecule/lutheran protein The receptor critical for sickle cell adhesion to laminin
... placental laminin (GIBCO BRL). Laminin binding assays were performed either at room temperature or at 37 8 C, whereas all other incubations were performed at room temper- ...For laminin ...
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Murine laminin binds to Histoplasma capsulatum A possible mechanism of dissemination
... 125I-labeled laminin revealed an estimated 3.0 x 10(4) binding sites per yeast with an apparent Kd for laminin binding of ...M. Laminin binding to ...
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Renal collecting system growth and function depend upon embryonic γ1 laminin expression
... exhibited laminin deficiency prior to mesenchymal tubular induction and either failed to develop a UB with involution of the mesenchyme, or developed small kidneys with decreased proliferation and branching, ...
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Phyto-polyphenols as potential inhibitors of breast cancer metastasis
... studies also suggest that they may actually possess charac- teristics of both (Yu & Di 2017). Driven by interleukin (IL)-4 and IL-10, tumor necrosis factor-alpha (TNFα), macrophage colony-stimulating factor (M-CSF), ...
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Keratinocyte-Secreted Laminin 5 Can Function as a Transient Receptor for Human Papillomaviruses by Binding Virions and Transferring Them to Adjacent Cells
... capsid binding to purified laminin ...2. Binding of HPV particles to purified ...LN5, laminin from human placenta (LNmix), BSA, or heparin- BSA (hep-BSA) as described in Materials and ...
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A systematic review of overlapping microRNA patterns in systemic sclerosis and idiopathic pulmonary fibrosis
... reduced compared to that in healthy controls. Importantly, they found that its overexpression in SSc fibroblasts is associated with decreased levels of mRNA and protein for type I and type III collagen, supporting a role ...
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VP23R of Infectious Spleen and Kidney Necrosis Virus Mediates Formation of Virus-Mock Basement Membrane To Provide Attaching Sites for Lymphatic Endothelial Cells
... to laminin and a putative transmembrane fragment, were found in all of the sequenced genomes of the members of ...AAL98747), laminin-like pro- tein gene of olive flounder iridovirus (GenBank accession ...
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Laminin Coating Promotes Calcium Phosphate Precipitation on Titanium Discs in vitro
... that laminin may be a bone stimulating coating agent is the possible interaction of the arginine-glycine-aspartic acid (RGD) motif with the integrin receptors of the surrounding ...of laminin as a ...
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Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion
... the binding site of the target [33], while LB-VS employs information of the known active compounds as a search query to retrieve the potential actives from large chemical libraries ...the binding mode of ...
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Embryonal carcinoma and the basement membrane glycoproteins laminin and entactin
... Int I De\ BioI 37 141~150t191} 3) 141 Embryonal carcinoma and the basement membrane glycoproteins laminin and entactin ALBERT E CHUNG* University of Pittsburgh, Department of Biological Sciences, Pitt[.] ...
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Laminin molecular domains which alter metastasis in a murine model
... the laminin receptor may be involved in hematogenous metastases ...whole laminin followed by tail vein injection increased tumor cell retention in the lung and strongly stimulated metastases ...the ...
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