Langerhans Cells
Morphometric analysis of CD1a positive Langerhans cells in the Human Tympanic Membrane.
... Langerhans cells and thymus derived T lymphocytes have always had a special affinity for each ...that Langerhans cells migrate through the afferent lymphatics to the draining lymph nodes, 37, ...
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Epidermal Langerhans cells tune skin reactivity to contact allergens
... of Langerhans cells (LCs), a population of epidermal dendritic cells, in immune responses to epicutaneously applied antigens has been ...these cells as key regulators of immunologic barrier ...
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Unique characterisation of Langerhans cells in the spleen of the African catfish (Clarias gariepinus)
... Despite Langerhans cells being relatively specific to epidermal tissues and some mucosal lined organs , these cells were present in healthy spleen/kidney tissues and diseased gills in salmonids ...
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Human Herpesvirus 8 Infects and Replicates in Langerhans Cells and Interstitial Dermal Dendritic Cells and Impairs Their Function
... dendritic cells (DC) in the skin and mucosa are Langerhans cells (LC) and interstitial dermal DC ...these cells to capture and process pathogens, we hy- pothesized that they could be infected ...
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CD1a-labeled Langerhans Cells in Gingival Pyogenic Granuloma and Fibroma Lesions: An Immunohistochemical Study
... that Langerhans cells play an important role in immune response and pathogenesis of reactive and inflamma- tory lesions of ...of Langerhans cells in reactive gingival overgrowths is not ...
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Activated CD34-Derived Langerhans Cells Mediate Transinfection with Human Immunodeficiency Virus
... Langerhans cells (LCs) comprise a distinct subset of DCs that reside within the genital epithelium and mucosal ...first cells to confront and recognize sex- ually transmitted pathogens ...these ...
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Evaluation of T cells & Langerhans Cells in Lichen Planus & Lichenoid Mucositis: Immunohistochemical study
... as Langerhans cells, stromal DC-SIGN+ DCs and PDCs, associated with a significant proportion of mature DCs, acquiring a CCR7+ 'migratory' phenotype, indicate that they may play a pivotal role in the ...
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Vaginal Langerhans Cells Nonproductively Transporting HIV-1 Mediate Infection of T Cells
... To overcome the limited yield of discrete LCs, we used multiple rounds of flow cytometric sorting (Fig. 1). After the first round of sorting into discrete LCs and LC-TC conjugates, discrete LCs were nearly pure (Fig. ...
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Autophagy links antimicrobial activity with antigen presentation in Langerhans cells
... labeling. Cells were treated with IFN-γ or left untreated in 10% human serum or 10% FCS ...Then, cells were washed and infected with live ...infection, cells were adhered to poly-L-lysine–coated ...
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Human immature Langerhans cells restrict CXCR4 using HIV 1 transmission
... Human primary LCs transmit predominantly R5 HIV-1 We have used an ex vivo tissue transmission model [30] to investigate the role of LCs in transmission of X4 and R5 HIV-1. Human epidermal sheets were exposed to dif- ...
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Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells
... T cells did not recognize LAM, nor any of the other previously identified lipid antigens presented by group 1 CD1 molecules, suggesting that a novel lipid antigen is presented by ...T cells (7, 9, 21, 38), ...
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The role of adhesion molecules in the migration of Langerhans cells
... blocked cells it w ould appear th at interactions w ith ECM proteins of the BM or the derm is of the skin are not required for the m aturational changes observed on the blocked ...
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A clinicopathologic study on calcifying epithelial odontogenic tumor: with special reference to Langerhans cell variant
... [20]. Langerhans cells are bone marrow- derived cells that migrate into the oral epithelium and serve as antigen-presenting ...that Langerhans cells may also migrate into the epithelial ...
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CD4, CD8 AND BCL2 Expression in Lichen Planus to Establish the relationship between Lymphocytic Exocytosis and Apoptosis
... CD8 T cells form the predominant population of the lymphocytic infiltrate with a significant proportion of Delta-gamma T cells [39] .PCR studies in Lichen planus potentially suggest the presence of auto ...
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Cutaneous immune responses mediated by dendritic cells and mast cells
... epidermal Langerhans cells to migrate toward skin-draining lymph nodes (reviewed extensively in ...of Langerhans cells is a multistep process involving sequential upregulation of CXCR4 and ...
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... epithelial cells migrating into the ...with cells undergoing ...of Langerhans cells in the gingiva as shown by Anjana R et ...epithelial cells were treated with cytokines which ...
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Morphology and Distribution of Dendritic Cells in Normal and Carcinoma Cervix
... Langerhans cells (LCs), a type of DCs are MHC class II expressing bone marrow derived ...immature cells on different epithelial tissues to detect invading pathogens or foreign antigens ...these ...
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Diminished transmission of drug resistant HIV 1 variants with reduced replication capacity in a human transmission model
... T cells are the pre- dominant target cells of HIV, it has been postulated that dendritic cells (DCs) naturally residing in the genital mu- cosa play a major role during sexual transmission ...mucosa, ...
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M protein and protein F act as important determinants of cell specific tropism of Streptococcus pyogenes in skin tissue
... different surface proteins of S. pyogenes play important roles in determining the cell-specific tropism of the bacterium in skin. Using streptococcal strains with defined mutations in the genes which encode surface ...
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Langerhans cell histiocytosis in adults: a case report and review of the literature
... examination includes print and pathological biopsy and immunohistochemical examination. Pathological materials can be taken from the rash, lymph nodes, the tumor or the local lesions. Langerhans cells were ...
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