leukocyte migration
Novel Anti-Inflammatory Peptides Based on Chemokine-Glycosaminoglycan Interactions Reduce Leukocyte Migration and Disease Severity in a Model of Rheumatoid Arthritis.
... is 10 amino acids) is a new approach to combating the chemokine – GAG interaction. Previous approaches have incorporated much more of the chemokine structure with knocked out GPCR activation and have included an ...
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Pregnant human peripheral leukocyte migration during several late pregnancy clinical conditions: a cross sectional observational study
... in leukocyte responsiveness to this factor [14, ...peripheral leukocyte responsiveness (as defined by migration) in response to term chemotactic factor ...peripheral leukocyte migration ...
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Identification and development of theraputic approaches in controlling transvascular leukocyte migration and inflammation in the CNS
... transendothelial migration of T-lymphocytes (section ...lymphocyte migration after 24 hours pre-treatment but not if inhibitors are present only during the 4 h lymphocyte migration assay ...affect ...
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Leptin and Adiponectin: new players in the field of tumor cell and leukocyte migration
... of migration of leukocytes and tumor cells. The migration of leukocytes is a key feature to fight cancer cells, whereas the locomotion of tumor cells is a prerequisite for tumor formation and ...in ...
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Soluble syndecan 3 binds chemokines, reduces leukocyte migration in vitro and ameliorates disease severity in models of rheumatoid arthritis
... increased leukocyte accumulation and disease severity ...blood leukocyte resulting in leukocyte migration into the RA ...chemokine-driven leukocyte migration and if they could ...
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Original Article Effect of exogenous galectin-1 on leukocyte migration: modulation of cytokine levels and adhesion molecules
... polymorphonuclear leukocyte (PMN) recruit- ment from the bloodstream to inflammatory sites through interactions with postcapillary venule endothelial cells ...cellular migration is triggered by a series of ...
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Prevention of leukocyte migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte associated antigen
... for leukocyte CD44 and L-selectin, respectively (41, 44), 4-F-GlcNAc anti-inflammatory efficacy may have been due to the downregulation of dermal HA and sialyl Lewis X antigen ...LC migration, we believe ...
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Khandoga, Alexander (2009): Mechanisms of leukocyte transendothelial and interstitial migration during inflammation in vivo. Dissertation, LMU München: Medizinische Fakultät
... of leukocyte directional interstitial migration in vivo Leukocyte migration toward the site of inflammation is critical for tissue injury and ...Although leukocyte interstitial ...
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Elevated Birth Rates in CD62L (L Selectin) Deficient BALB/c Mice: Potential Involvement of NK Cells
... parallels leukocyte transmigration, suggesting that the mo- lecular basis of these processes might be ...for leukocyte (L)-selectin (CD62L) in the inflammatory ...initiating leukocyte ...
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Monocytes Regulate T Cell Migration through the Glia Limitans during Acute Viral Encephalitis
... CNS leukocyte entry under physiological conditions ...While leukocyte entry into the CNS parenchyma is beneficial in controlling microbial infections, dysregulated recruitment is associated with chronic ...
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In vivo temporal and spatial profile of leukocyte adhesion and migration after experimental traumatic brain injury in mice
... that leukocyte infiltration into the tissue was correlated to histological outcome after fluid percussion injury (FPI) ...inhibit leukocyte- endothelium adhesion; most importantly, this reduction in ...
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Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma
... transendothelial migration of monocytes into neural tissue of the eye after IOP elevation and to suggest a primary importance of this monocyte entry for glaucomatous neural ...damage. Leukocyte ...
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T lymphocyte recruitment by interleukin 8 (IL 8) IL 8 induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo
... agents (IL-8, FMLP, and PMA) in the NDCF preparations makes if difficult to determine whether the granule products alone are responsible for cell migration or whether this migra- tion is influenced or occurs in ...
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Effects of levamisole on normal and abnormal leukocyte locomotion
... monophosphate shunt activity in neutrophils, but did not alter chemotactic factor-induced changes in the surface charge of neutrophils. Other concentrations of levamisole did not affect leukocyte locomotion except ...
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Coatings on mammalian cells: interfacing cells with their environment
... More frequently, LBL cell patches are created with the intention of cell-directed drug delivery, and these “ back- packs” of drugs are manufactured by the sequential deposition of polymer release, drug payload and cell ...
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PD-1 and PD-L1 correlated gene expression profiles and their association with clinical outcomes of breast cancer
... We subsequently identified co-expressed genes of PD-1 and PD-L1 by means of WGCNA. A total of 1065 genes correlated with PD-1 and 99 PD-L1 correlated genes were screened. The GO enrichment analysis of PD-1 correlated ...
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Post-translational modification-regulated leukocyte adhesion and migration
... the leukocyte, termed the uropod, detaches itself from the underlying substratum and undergoes retraction to facilitate forward movement of the ...for migration, it has been implicated in promoting shape ...
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Drug-induced interstitial lung disease: mechanisms and best diagnostic approaches
... One method to confirm the diagnosis of a drug-induced disease is re-exposure or re-test of the drug. However, clinicians are reluctant to place patients at further risk of illness, particularly in cases with severe ...
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Novel Aspects of Fibrin(ogen) Fragments during Inflammation
... Coagulation is fundamental for the confinement of infection and/or the inflammatory response to a limited area. Under patho- logical inflammatory conditions such as arthritis, multiple sclerosis or sepsis, an ...
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Selectin and selectin ligand binding: a bittersweet attraction
... of leukocyte migration into target organs has long been an attractive, though challenging, basis for anti-inflammatory ...of leukocyte rolling along blood vessels has not yielded successful new ...
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