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Lewy bodies

Dementia with Lewy bodies: an update and outlook

Dementia with Lewy bodies: an update and outlook

... with Lewy bodies (DLB) is an age-associated neurodegenerative disorder producing progressive cognitive decline that interferes with normal life and daily ...in Lewy bodies and Lewy ...

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FDG-PET in suspected dementia with Lewy bodies: a case report

FDG-PET in suspected dementia with Lewy bodies: a case report

... involvement of occipital cortices is not solely found in patients with DLB as it is also seen in PD and PDD. This observation could be due to the fact that all three dis- eases share the same pathology of Lewy ...

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Visual signs and symptoms of dementia with Lewy bodies

Visual signs and symptoms of dementia with Lewy bodies

... with Lewy bodies (DLB) (also known as 'Lewy body dementia' or ‘diffuse Lewy body disease') is the second most common form of dementia after Alzheimer’s disease (Alzheimer’s disease) 3,4 and ...

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Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

... that Lewy bodies may protect affected neurons from death and furthers the notion that profound alterations in cytoplasmic-nuclear trafficking are a key element of the neurodegenerative process ...

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Neural correlates of visual hallucinations in dementia with Lewy bodies

Neural correlates of visual hallucinations in dementia with Lewy bodies

... As in the study by Nagahama et al. [10], the left cingu- lum was implicated in our study, whereas the right hemisphere has been observed to be more particularly affected in most studies. Nevertheless, we noted bilateral ...

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ATP13A2 (PARK9) protein levels are reduced in brain tissue of cases with Lewy bodies

ATP13A2 (PARK9) protein levels are reduced in brain tissue of cases with Lewy bodies

... Comparison of immunoperoxidase localization of ATP13A2 in anterior cingulate cortex between PD and DLB cases and controls was performed, as a recent study suggested in- creased ATP13A2 protein expression in a Lewy ...

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Abnormal daytime sleepiness in dementia with Lewy bodies compared to Alzheimer’s disease using the Multiple Sleep Latency Test

Abnormal daytime sleepiness in dementia with Lewy bodies compared to Alzheimer’s disease using the Multiple Sleep Latency Test

... Patients were consecutively recruited through the Neur- ology and Neuropsychology clinics at the Mayo Clinic and enrolled as part of the Mayo Clinic’s Alzheimer’s Disease Research Center (ADRC; Jacksonville, FL, and ...

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Clinical features of dementia with lewy bodies in 35 Chinese patients

Clinical features of dementia with lewy bodies in 35 Chinese patients

... with lewy bodies (DLB) is the second most prevalent cause of degenerative dementia after Alzheimer disease (AD) in older people, accounting for 10% of all cases ...are Lewy bodies (LBs), ...

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An unusual delusion of duplication in a patient affected by Dementia with Lewy bodies

An unusual delusion of duplication in a patient affected by Dementia with Lewy bodies

... Background: Dementia with Lewy bodies (DLB) is the second most frequent diagnosis of progressive degenerative dementia in older people. Delusions are common features in DLB and, among them, Capgras syndrome ...

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The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis

The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis

... with Lewy bodies Prior to any discussion of the probable biomarkers of prodromal DLB, the temporal development of LB path- ology must be ...for Lewy pathology in PD ...

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Alpha synuclein in the neurodegenerative mechanisms of Parkinson's disease and dementia with Lewy bodies

Alpha synuclein in the neurodegenerative mechanisms of Parkinson's disease and dementia with Lewy bodies

... Due to a lack of specific and accessible biomarkers, PD cannot be definitively diagnosed until Lewy bodies are identified in the SN at autopsy. However, a significant proportion of the aged population have ...

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Cerebral Microbleeds in Patients with Dementia with Lewy Bodies and Parkinson Disease Dementia

Cerebral Microbleeds in Patients with Dementia with Lewy Bodies and Parkinson Disease Dementia

... with Lewy bodies ...with Lewy bodies group ...with Lewy bodies group was significantly associated with the presence of lobar cerebral microbleeds after adjusting for age, sex, ...

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Amyloid-β peptides in cerebrospinal fluid of patients with dementia with Lewy bodies

Amyloid-β peptides in cerebrospinal fluid of patients with dementia with Lewy bodies

... characterized neuropathologically by the accumulation of α -synuclein aggregates in Lewy bodies and Lewy neurites throughout the brain [3]. In addition, DLB patients often have some degree of ...

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Improving the identification of dementia with Lewy bodies in the context of an Alzheimer’s-type dementia

Improving the identification of dementia with Lewy bodies in the context of an Alzheimer’s-type dementia

... of Lewy bodies (LBs) in the cortex of people with dementia was first reported by Okazaki et ...with Lewy bodies (DLB) as a clinicopathologi- cal entity distinct from Alzheimer’s disease (AD) ...

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Cognitive and affective theory of mind in dementia with Lewy bodies and Alzheimer’s disease

Cognitive and affective theory of mind in dementia with Lewy bodies and Alzheimer’s disease

... The first publications about ToM reported studies on patients with autism [7] or schizophrenia [8]. In the 2000s, researchers began to assess ToM in neurological diseases. One of the first of these studies was by Gregory ...

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Dementia with Lewy bodies: The investigation of pre- and post-synaptic dopaminergic receptors with SPET

Dementia with Lewy bodies: The investigation of pre- and post-synaptic dopaminergic receptors with SPET

... Hallucinations and signs of parkinsonism help distinguish patients with dementia and cortical Lewy bodies from patients with Alzheimer's disease at presentation: a clinicopathological[r] ...

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Demography, diagnostics, and medication in dementia with Lewy bodies and Parkinson's disease with dementia: data from the Swedish Dementia Quality Registry (SveDem)

Demography, diagnostics, and medication in dementia with Lewy bodies and Parkinson's disease with dementia: data from the Swedish Dementia Quality Registry (SveDem)

... in dementia with Lewy bodies and Parkinson’s disease with dementia: data from the Swedish Dementia Quality Registry (SveDem).. Seyed-Mohammad Fereshtehnejad 1.[r] ...

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Development and validation of a screening instrument for cognitive fluctuation in patients with neurocognitive disorder with Lewy bodies (NCDLB): the Mayo Fluctuations Scale-Thai version

Development and validation of a screening instrument for cognitive fluctuation in patients with neurocognitive disorder with Lewy bodies (NCDLB): the Mayo Fluctuations Scale-Thai version

... Papan Thaipisuttikul, M.D. is an assistant professor and geriatric psychiatrist in the Department of Psychiatry, Faculty of Medicine Ramathibodi Hospital, Mahidol University in Bangkok, Thailand. She received her medical ...

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Cognitive fluctuations in connection to dysgraphia: a comparison of Alzheimer’s disease with dementia Lewy bodies

Cognitive fluctuations in connection to dysgraphia: a comparison of Alzheimer’s disease with dementia Lewy bodies

... cognitive impairment and the performance of handwritten scripts presented as “letter-writing” to a close relative by patients with dementia Lewy bodies (DLB), as fluctuations of the sym[r] ...

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Biomarkers in biological fluids for dementia with Lewy bodies

Biomarkers in biological fluids for dementia with Lewy bodies

... Dementia with Lewy bodies (DLB) has become the second most common neurodegenerative dementia due to demographic ageing. Differential diagnosis is still troublesome especially in early stages of the disease, ...

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