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Leydig cells

Dexamethasone suppresses the differentiation of stem Leydig cells in rats in vitro

Dexamethasone suppresses the differentiation of stem Leydig cells in rats in vitro

... steroidogenic Leydig cell-like cells by transcriptionally promoting the expression of steroido- genic enzymes including Cyp17a1 [34, ...fetal Leydig cells thus down-regulating Cyp17a1 ...

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The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells

The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells

... Recombinant insulin appropriate for mouse cell cul- ture experiments was obtained from Sigma-Aldrich as a lyophilised powder. As per manufacturer’s instructions, the powder was reconstituted in 0.01 M hydrochloric acid ...

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Development of in vitro culture of rat Leydig cells after purification with Nycodenz gradient

Development of in vitro culture of rat Leydig cells after purification with Nycodenz gradient

... as Leydig cells transplantation which naturally produced testosterone that can be used to replace the use of syn- thetic testosterone hormone ...and cells. Therefore, Leydig cell culture is ...

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Article:  Seasonal cycle of leydig cells in the Japanese Jungle Crow (Corvus macrorhynchos)

Article: Seasonal cycle of leydig cells in the Japanese Jungle Crow (Corvus macrorhynchos)

... of Leydig cells at various periods of sexual ...glandular cells is in direct proximity to recrudescence of spermatogenic cells in upcoming breeding ...that Leydig cells become ...

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Ethanolic Extracts of Young Papaya Seed (Carica papaya, Linn) Decrease Spermatocytes, Leydig Cells, and Androgen Receptor of Leydig Cells of Adult Mice (Mus musculus)

Ethanolic Extracts of Young Papaya Seed (Carica papaya, Linn) Decrease Spermatocytes, Leydig Cells, and Androgen Receptor of Leydig Cells of Adult Mice (Mus musculus)

... In this study, the average expression of androgen receptors in the Leydig cells in the treatment group was 28.11±3.06%, compared to 55.07±2.49% that we found in the control group. The mechanism that may be ...

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Leydig Cells Encapsulation with Alginate Chitosan: Optimization of Microcapsule Formation

Leydig Cells Encapsulation with Alginate Chitosan: Optimization of Microcapsule Formation

... the Leydig cells, we focused on the osmolality and viscosity of the solutions ...for cells due to its relation to the osmotic process on the ...of cells and the capsules will ensure that the ...

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Previously claimed male germline stem cells from porcine testis are actually progenitor Leydig cells

Previously claimed male germline stem cells from porcine testis are actually progenitor Leydig cells

... ES-like cells; ICSI: Intracytoplasmic sperm injection; ITS: Insulin-transferrin-selenium; KEGG: Kyoto encyclopedia of genes and genome; LH: Luteinizing hormone; LHR: LH receptor; LIF: Leukemia inhibitory factor; ...

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Detection of hCG responsive expression of the steroidogenic acute regulatory protein in mouse leydig cells

Detection of hCG responsive expression of the steroidogenic acute regulatory protein in mouse leydig cells

... MA-10 cells with a cAMP analog coordinately increased StAR mRNA, StAR protein and steroid production (10, 20, ...mouse Leydig cells, thyroid hormone has been reported to increase the levels of StAR ...

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Original Article Regulation of lipid metabolism in rat leydig cells testosterone synthesis and proliferation

Original Article Regulation of lipid metabolism in rat leydig cells testosterone synthesis and proliferation

... der and obesity appeared in more and more people, also, the function of the male reproduc- tive system had a certain negative affect by the abnormal lipid metabolism. Researches showed that people with obesity disorders, ...

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Microscopic Anatomy of Sertoli and Leydig Cells During Fetal Development in Baladi Rabbit

Microscopic Anatomy of Sertoli and Leydig Cells During Fetal Development in Baladi Rabbit

... endocrine cells of rabbit fetus were grouped into small or large clusters that occupied parts of the spaces between the developing testicular ...the Leydig cells at late fetal period of rabbit are ...

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Estrogen Dependence of a Gonadotropin induced Steroidogenic Lesion in Rat Testicular Leydig Cells

Estrogen Dependence of a Gonadotropin induced Steroidogenic Lesion in Rat Testicular Leydig Cells

... stimulation, rather than the extent of LH receptor loss, was responsible for the steroidogenic lesion. A role of estradiol in the enzymatic block produced in vivo by acute elevation of circulating gonadotropin ...

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INVESTIGATION OF THE EFFECTS OF KIGELIA AFRICANA (LAM ) BENTH  EXTRACTS ON TM3 LEYDIG CELLS

INVESTIGATION OF THE EFFECTS OF KIGELIA AFRICANA (LAM ) BENTH EXTRACTS ON TM3 LEYDIG CELLS

... the cells were treated with trypsin, centrifuged, resuspended in 3 ml fresh complete medium, they were then counted using hemocytometer ...TM3 Leydig cells (100 µl) were seeded at 5×10 3 cells ...

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Effects of treatment with Astragalus Membranaceus on function of rat leydig cells

Effects of treatment with Astragalus Membranaceus on function of rat leydig cells

... rat Leydig cells Testes were excised sterilely from male rats (n = 3) following euthan- asia and placed in PBS (pH ...DMEM. Leydig cells were dispersed by pipetting followed by centrifugation ...

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Estrogenic in vitro assay on mouse embryonic Leydig cells

Estrogenic in vitro assay on mouse embryonic Leydig cells

... caused 4.0 ± 0.5-fold increase of ERE-Luc activity in fractions enriched in embryonic Leydig cells in our assay. Not consistent inhibitory effect of ICI on the MEHP effect (Fig. 5A) suggests complex not ...

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The Role of Foxo3 in Leydig Cells

The Role of Foxo3 in Leydig Cells

... in Leydig cells, R2C cells were treated with luteinizing hormone (LH) and the phosphorylation of ...of Leydig cells; however, at PPW 5, Foxo3 was expressed in both the nucleus and ...

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Fetal Leydig cells dedifferentiate and serve as adult Leydig stem cells

Fetal Leydig cells dedifferentiate and serve as adult Leydig stem cells

... differentiated Leydig cells spontaneously return to the undifferentiated ...postnatal Leydig cell population, neonatal Leydig cells (Teerds and Huhtaniemi, ...adrenal cells. A ...

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Effect of supraphysiological dose of Nandrolone Decanoate on the testis and testosterone concentration in mature and immature male rats: A time course study

Effect of supraphysiological dose of Nandrolone Decanoate on the testis and testosterone concentration in mature and immature male rats: A time course study

... spermatogenic cells, Leydig cells and Sertoli cells, the method described was used ...of cells values per cross section of the seminiferous tubules was quantified, it was possible to ...

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CHRONIC MELATONIN APPLICATION MODIFIES THE CYTOARCHITECTURE OF
TESTIS AND DECREASES THE SPERM NUMBER IN WISTAR RAT

CHRONIC MELATONIN APPLICATION MODIFIES THE CYTOARCHITECTURE OF TESTIS AND DECREASES THE SPERM NUMBER IN WISTAR RAT

... The results of the present study suggested that melatonin has an adverse effect on male reproductive apparatus in rats. Melatonin did not cause a significant decrease in testis weight but it did change the seminiferous ...

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Evaluation of the leptin receptor in human spermatozoa

Evaluation of the leptin receptor in human spermatozoa

... Sertoli cells of adult rats [20] while leptin receptor immunoreactivity is confined to the Leydig cells of rats and the germ cells of mice [21,22] In addition, leptin receptor are present in ...

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GOLPH2 expression may serve as diagnostic marker in seminomas

GOLPH2 expression may serve as diagnostic marker in seminomas

... germ cells in non-neoplastic tubules were either negative or displayed a patchy slightly positive GOLPH2 ...these cells from other interstitial cells and from the intratubu- lar ...the Leydig ...

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