The link between IL-5, eosinophilia and disease
Secreted Respiratory Syncytial Virus G Glycoprotein Induces Interleukin-5 (IL-5), IL-13, and Eosinophilia by an IL-4-Independent Mechanism
... of IL-5, IL-13, and pulmonary eosinophilia by mechanisms which op- erate independently of ...severe disease upon RSV challenge and similar profiles of cytokine induction and recruitment ...
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Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease
... with eosinophilia juvenile Scnn1b-Tg mice with muco-obstructive lung ...airways disease, however, its role in eosinophilic inflammation in muco- obstructive lung disease remains ...of IL-1R ...
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IL-5-Deficient Mice Have a Developmental Defect in CD5 + B-1 Cells and Lack Eosinophilia but Have Normal Antibody and Cytotoxic T Cell Responses
... the IL-5-deficient mice described in the present work have provided an unique model to investigate the role of IL-5 in B cell development and antibody production as well as the role of ...
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Circulating, but not local lung, IL 5 is required for the development of antigen induced airways eosinophilia
... systemic IL-5 in the patho- genesis of allergic airways eosinophilia, we first examined the cellular and cytokine responses in OVA-sensitized and chal- lenged IL-5–deficient ...in ...
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Relationship between interleukin 5 and eotaxin in regulating blood and tissue eosinophilia in mice
... cooperation between IL-5 and eotaxin for the selective accumulation of eosinophils at sites of allergic inflammation is ...used IL-5 deficient mice to define the relationship ...
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The link between chronic pain and Alzheimer’s disease
... relationship between the intensity of pain and develop- ing dementia [29], which may be due to (1) dementia pa- tients and their caregivers routinely underreport pain intensity, (2) chronic pain may manifest ...
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Oxidative stress: a possible link between periodontal disease and cardiovascular disease
... Current epidemiological data show associations between cardiovascular disease and periodontitis. These associations would be predicted based on inflammatory mechanisms initiated by bacteria associated with ...
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Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease
... of IL-1β, improves clearance of Aβ by microglia and cognitive performance in AD mice ...cytokine IL-33 present lower levels of pro-inflammatory gene expression (i.e., IL-1β, IL-6, NLRP3) in ...
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The relationship between eosinophilia and slow coronary flow
... association between eosinophil count and the number of affected vessels, which have ...heart disease and found that high viscosity is an independent predictor of both in-hospital and long-term adverse ...
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Eosinophilia and Risk of Incident End Stage Kidney Disease
... Several factors should be considered in the interpretation of our ndings. We believe our study highlights new information that has not been evaluated between eosinophilia and ESKD, speci cally the higher ...
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Determination of the relationship between the severity of Behcet's disease and the expression and methylation of IL-10, IL-6 and IL-8 genes
... Materials and Methods This case-control study was performed on 47 patients with Behcet and 61 healthy individualsduring 2015-2017. All patients were chosen from Azeri population of the country (people of Azerbaijan ...
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Exploring the link between neurological disease and artistic style in painters
... By first outlining the hypothesized neuroanatomical bases of creativity, the discussion then relates localized brain damage to various stylistic changes in painters and previously non-artists. It also explores artistic ...
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The link between periodontal disease and rheumatoid arthritis: An updated review
... a disease process involving progressive destruction of the tissues that support the ...mechanistic link between periodontitis and RA, diseases that are known to be significantly associated at the ...
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Epidemiological Link between Gastric Disease and Polymorphisms in VacA and CagA
... This perhaps occurs through CagA preventing VacA-induced apoptosis (37, 56) or by inhibiting the autophagy pathway in- duced by VacA (50). CagA and VacA are the two best-studied virulence factors of H. pylori. ...
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A causative link between periodontal disease and glomerulonephritis: a preliminary study
... ing IL-6 and TNF- α ...of IL-1, IL-6, and TNF- α have been detected on mesangial cell and epithe- lial cells which, in turn, induce glomerular ...of IL-1 β and IL-6 by glomerular ...
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Crohn's disease: is there any link between anal and luminal phenotypes?
... luminal disease at diagnosis were not significantly different between the various phenotypes of ...found between anal stricture and stricturing Montreal phenotype (B2) (N = 3/49, p = ...found ...
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IL 17/IL 10 double producing T cells: new link between infections, immunosuppression and acute myeloid leukemia
... into IL-17/IL-10-secreting cells, creating an environment with reduced immune control and thus probably favoring leukemia immune ...nection between the severe infective problems of AML patients and ...
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Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease
... Alzheimer's disease (AD) is accompanied by a chronic inflammatory process, including activation of microglia and astrocytes that express pro-inflammatory cytokines ...the disease. Two multi-functional ...
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Airway allergen exposure stimulates bone marrow eosinophilia partly via IL-9
... of IL-9 in in vitro studies of allergic cellular processes [23-25], the treatment with a neutraliz- ing anti-IL-9 antibody in vivo in our study did not protect airways from the abundant eosinophilia ...
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Awareness of link between smoking and periodontal disease in Nigeria: a comparative study
... This is more so because the periodontal effects of smoking, although manifested locally, are systemically mediated. This systemic mediation is via humoral, hematologic, vascular, microbiologic, and direct toxic effects ...
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