linkage disequilibrium
Homozygosity and Linkage Disequilibrium
... of linkage disequilibrium and systematic data are collected (Kidd et ...of disequilibrium ceived a great deal of ...example, disequilibrium between markers was used to one needs to refer to a ...
14
Linkage Disequilibrium and the Mapping of Human Disease Genes
... Abstract: Identification of human disease genes can be accomplished by two strategies: functional cloning and positional cloning. Genetic mapping is the localization of genes underlying phenotypes on the basis of ...
9
Detecting Linkage Disequilibrium in Bacterial Populations
... for linkage using Monte Carlo simulation can be very time ...reveals linkage disequilibrium where linkage equilibrium has previously been ...
8
Characterizing Linkage Disequilibrium in Pig Populations
... Linkage disequilibrium (LD), defined as non-random association of alleles at two or more loci, in a population can be used to exploit what has happened to the population ...
13
Coalescence and Linkage Disequilibrium in Facultatively Sexual Diploids
... lower linkage disequilibrium, which can be measured from genomic data (Griffiths 1981; Hudson and Kaplan 1985; Hudson 1990; Simonsen and Churchill 1997; McVean ...which linkage disequi- librium is ...
19
How Population Growth Affects Linkage Disequilibrium
... ABSTRACT The “LD curve” relates the linkage disequilibrium (LD) between pairs of nucleotide sites to the distance that separates them along the chromosome. The shape of this curve reflects natural selection, ...
13
A Scan for Linkage Disequilibrium Across the Human Genome
... Linkage disequilibrium (LD), the tendency for alleles of linked loci to co-occur nonrandomly on chromosomal haplotypes, is an increasingly useful phenomenon for (1) revealing historic perturbation of ...
12
The detection of linkage disequilibrium in molecular sequence data.
... Even though the usual test for linkage disequilibrium is not useful €or very asymmetrical allele frequencies, it might be possible to use such data to detect an overall excess of [r] ...
12
LINKAGE DISEQUILIBRIUM IN A FINITE POPULATION THAT IS PARTIALLY SELFING
... Formulas for the expected sum of squares of the linkage disequilibria and the squared standard linkage disequilibrium are derived from the equilibrium values of sixteen inb[r] ...
13
Joint Linkage and Linkage Disequilibrium Mapping of Quantitative Trait Loci in Natural Populations
... as linkage disequilibrium) studies are two major approaches for mapping genes that control simple or complex traits in plants, animals, and ...of linkage analysis and linkage ...
14
Linkage Disequilibrium as a Signature of Selective Sweeps
... (iii) linkage disequilibrium (LD) around the basis of adaptation and phenotypic evolution of the site where the substitution of a beneficial allele took ...
12
Handling linkage disequilibrium in linkage analysis using dense single nucleotide polymorphisms
... of linkage disequilibrium violates the underlying assumption of linkage equilibrium in most traditional multipoint linkage ...trait linkage analysis when parental genotypes are ...
5
The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium
... the linkage disequilibrium between local ancestry tracks of individuals in an admixed ...ancestry linkage disequilibrium (LAD) and the variance of ancestry in a population as a function of the ...
9
Inferring Coancestry in Population Samples in the Presence of Linkage Disequilibrium
... pedigree linkage studies and in population-based association studies there has been much interest in the use of modern dense genetic marker data to infer segments of gene identity by descent (ibd) among ...
17
The Extent of Linkage Disequilibrium Caused by Selection on G6PD in Humans
... The gene coding for glucose-6-phosphate dehydrogenase (G6PD) is subject to positive selection by ma- laria in some human populations. The G6PD A allele, which is common in sub-Saharan Africa, is associated with deficient ...
11
Insights Into Recombination From Patterns of Linkage Disequilibrium in Humans
... of linkage disequilibrium (LD) between linked markers would facilitate the design of association studies and help to distinguish between evolutionary ...
12
Analysis of Multilocus Linkage Disequilibrium Structure in the Human Genome
... or linkage disequilibrium (LD) mapping aims to estimate the locations of genetic variants on chromosome in a much finer scale and predict their genetic ...
155
Linkage disequilibrium in natural and experimental populations of Drosophila melanogaster.
... We conclude that linkage disequilibrium in these populations is most likely due to natural selection acting on the allozymes, or on loci very tightly linked to them.. A NIMAL and[r] ...
9
Linkage Disequilibrium Under Recurrent Bottlenecks
... ABSTRACT To model deviations from selectively neutral genetic variation caused by different forms of selection, it is necessary to fi rst understand patterns of neutral variation. Best understood is neutral genetic ...
13
A Genealogical Interpretation of Linkage Disequilibrium
... of sample chromosomes. One advantage of writing the This is the same result as given by Ohta and Kimura expression in terms of correlations rather than covari- (1971) and Weir and Hill (1986) and is the expected ances is ...
6