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Lipid Accumulation

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

... question. Lipid accumulation in primary human hepatocytes was induced by incubation with oleic ...Similarly, lipid peroxidation, oxidative stress and pro-inflammatory gene expression as well as ...

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Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation

Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation

... hepatic lipid accumulation in parkin KO mice, we analyzed the genetic expression of the principal factors related to lipogenesis, fatty acid uptake, and β-oxidation in the ...and lipid uptake (CD36) ...

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Growth and lipid accumulation by different nutrients in the microalga Chlamydomonas reinhardtii

Growth and lipid accumulation by different nutrients in the microalga Chlamydomonas reinhardtii

... oil accumulation under T-N was strictly depend- ent on the available external acetate supply and the amount of oil increased steadily as the acetate concen- tration increased to the levels several-fold higher than ...

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Effects and mechanisms of apolipoprotein A-V on the regulation of lipid accumulation in cardiomyocytes

Effects and mechanisms of apolipoprotein A-V on the regulation of lipid accumulation in cardiomyocytes

... including the skeletal muscle, pancreatic β-cell, and heart tissue. Recently, Luo et al. found that the tran- scription and protein levels of important proteins in FA uptake and oxidation were reduced in PPARγ deficient ...

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Lipid accumulation and utilization during microcycle growth of Aspergillus niger

Lipid accumulation and utilization during microcycle growth of Aspergillus niger

... Similarly, lipid accumulation occurred in Candida 107 grown on a medium with a high carbon : nitrogen ...for lipid synthesis. The mechanism of lipid accumulation cannot be attributed to ...

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Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man

Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man

... hepatic lipid accumula- tion ...hepatic lipid accumulation ...to lipid accumu- lation in specific subgroups of pa- tients with NAFLD and might be more relevant than circulating NEFAs ...

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Lipid accumulation product or lap as an up-to-date clinical biochemical marker of human obesity

Lipid accumulation product or lap as an up-to-date clinical biochemical marker of human obesity

... So, LAP index is a marker that reflects joint anatomic and biochemical changes that are related to excessive lipid accumulation in a body. It is an appropriate instrument to de- tect predisposition to ...

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A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic Steatohepatitis

A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic Steatohepatitis

... to lipid accumu- lation in the liver, including excessive supply of FFAs which accounted for almost two-thirds of the accu- mulation, decreased very low density lipopro- tein-triglyceride export, increased de novo ...

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In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish

In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish

... fluorescent lipid marker to the transgenic zebrafish resulted in vascular lipid accumulation, quantified in live animals using confocal ...vascular accumulation of IK17-specific MDA ...

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Pten/yap mediated lipid accumulation in podocytes contributes to glomerulosclerosis

Pten/yap mediated lipid accumulation in podocytes contributes to glomerulosclerosis

... Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a vital tumor suppressor involved in cell proliferation, survival, and motility.(19, 20) PTEN played a critical role in podocyte injury.(21-23) In our ...

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MondoA drives muscle lipid accumulation and insulin resistance

MondoA drives muscle lipid accumulation and insulin resistance

... neutral lipid accumulation in extra-ad- ipose tissues, such as skeletal muscle and liver ...intramyocellular lipid accumulation and the development of insulin resistance are incompletely ...

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Artemisinin Reduces Lipid Accumulation in Hepatocytes by Inhibition of CD36 Expression

Artemisinin Reduces Lipid Accumulation in Hepatocytes by Inhibition of CD36 Expression

... on lipid accumulation in an in vitro model of ...OA. Lipid and TAG contents were measured by Oil Red O staining and enzymatic ...intracellular lipid accumulation and TAG concentration ...

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Lipid accumulation from glucose and xylose in an engineered, naturally oleaginous strain of Saccharomyces cerevisiae

Lipid accumulation from glucose and xylose in an engineered, naturally oleaginous strain of Saccharomyces cerevisiae

... increased lipid accumulation by deleting the global regulator SNF1 as it has previously been shown to play an important role in lipid accumulation in both ...for lipid ...

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Lipid accumulation in response to nitrogen limitation and variation of temperature in Nannochloropsis salina

Lipid accumulation in response to nitrogen limitation and variation of temperature in Nannochloropsis salina

... algal lipid accumulation and the conditions applied in these studies differ ...in lipid content may be species and strain specific (El-Baky et ...increasing lipid production (Lombardi and ...

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Comparison of body mass index and lipid accumulation product as a better indicator of metabolic syndrome

Comparison of body mass index and lipid accumulation product as a better indicator of metabolic syndrome

... Lipid Accumulation product (LAP) a novel and simple index of central lipid accumulation based on a combination of waist circumference (WC) and serum triglycerides ...

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miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease

miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease

... Moreover, lipid accumulation in circulating monocytes was significantly reduced in TLR4-deficient ...regulating lipid deposition ...regulated lipid-laden macrophage foam cell formation, TLR4 ...

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Leucine Biosynthesis Is Involved in Regulating High Lipid Accumulation in Yarrowia lipolytica

Leucine Biosynthesis Is Involved in Regulating High Lipid Accumulation in Yarrowia lipolytica

... (IPM) accumulation, which is indicative of leucine depletion ...in lipid accumulation ...enhances lipid accumulation by increasing the flux through ...increases lipid ...

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Lipid accumulation, lipid oxidation, and low plasma levels of acquired antibodies against oxidized lipids associate with degeneration and rupture of the intracranial aneurysm wall

Lipid accumulation, lipid oxidation, and low plasma levels of acquired antibodies against oxidized lipids associate with degeneration and rupture of the intracranial aneurysm wall

... out lipid accumulation (Oil-Red-O staining) separately (n = 148 from 38 aneurysms), as well as from areas with and without oxidized LDL (immunostaining with YE anti- body against copper oxidized LDL) ...

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Characterization and optimization of endogenous lipid accumulation in Chlorella vulgaris SDEC-3M ability to rapidly accumulate lipid for reversing nightly lipid loss

Characterization and optimization of endogenous lipid accumulation in Chlorella vulgaris SDEC-3M ability to rapidly accumulate lipid for reversing nightly lipid loss

... media, lipid syn- thesis in darkness consumes or reserves energy and car- bon sources derived only from cells themselves, namely endogenous lipid ...studies, lipid content elevated by N-deficiency ...

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Salvia hispanica L. (chia) seeds oil extracts reduce lipid accumulation and produce stress resistance in Caenorhabditis elegans

Salvia hispanica L. (chia) seeds oil extracts reduce lipid accumulation and produce stress resistance in Caenorhabditis elegans

... study lipid metabolism and antioxidant effects of chia seeds oil extracts the use of a simple model with ease of manipulation as Caenorhabditis elegans can be of great advantage ...to lipid metabolism ...

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