Lipid Core
Methotrexate-loaded lipid-core nanocapsules are highly effective in the control of inflammation in synovial cells and a chronic arthritis model
... properties of LNC as a new drug-delivery system, the aims of our investigations were to evaluate whether methotrexate- loaded lipid-core nanocapsules (MTX-LNC) prepared in a liquid-dos[r] ...
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α-bisabolol-loaded lipid-core nanocapsules reduce lipopolysaccharide-induced pulmonary inflammation in mice
... Abstract: Acute respiratory distress syndrome (ARDS) is a severe clinical condition of respiratory failure due to an intense inflammatory response with different etiologies. Despite all efforts, therapy remains limited, ...
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Labeling the oily core of nanocapsules and lipid core nanocapsules with a triglyceride conjugated to a fluorescent dye as a strategy to particle tracking in biological studies
... nanocapsules, lipid-core nanocapsules, or surface charge, ...or lipid-core nanocapsules (LNC), using the labeled oil and Eudragit RS100, Eudragit S100, or poly(caprolactone) (PCL), ...
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Melatonin-loaded lipid-core nanocapsules protect against lipid peroxidation caused by paraquat through increased SOD expression in Caenorhabditis elegans
... in lipid peroxidation in the brain and liver of Wistar ...melatonin-loaded lipid-core nano- capsules (Mel-LNC), prepared with PCL, presented pro- tective effects against cytotoxicity and genotoxicity ...
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Role of poly(ε-caprolactone) lipid-core nanocapsules on melanoma–neutrophil crosstalk
... Abstract: Metastatic melanoma is an aggressive cancer with increasing incidence and limited therapies in advanced stages. Systemic neutrophilia or abundant neutrophils in the tumor con- tribute toward its worst ...
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Novel therapeutic mechanisms determine the effectiveness of lipid-core nanocapsules on melanoma models
... effectiveness. Lipid-core nanocapsules (LNCs), prepared with poly(ε-caprolactone), capric/caprylic triglyceride, and sorbitan monostearate and stabilized by polysorbate 80, are efficient as drug delivery ...
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Bacteriophage PM2 Has a Protein Capsid Surrounding a Spherical Proteinaceous Lipid Core
... purified protease-treated particles. Determination of the N- terminal amino acid sequences of these degradation products (resulting in the sequence MIVKKKLAAG) revealed that the ⬃18-kDa protein fragment in proteinase ...
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Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment
... We investigated the efficacy of methotrexate-loaded lipid-core nanocapsules (MTX-LNC) administered by the oral route to treat murine GBM, its ability to cross the BBB, and the mechanis[r] ...
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Chitosan-Coated Nanoparticles: Effect of Chitosan Molecular Weight on Nasal Transmucosal Delivery
... simvastatin-loaded lipid-core nanocapsules were prepared according to the interfacial deposition of pre-formed polymer method already reported in literature ...
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Peptide-based subunit vaccine against hookworm infection
... LCP core alone clearly did not form helical structure (Figure ...of lipid core peptides LCP-1and ...of lipid core peptides (LCP) was measured by comparing the absorbance (540 nm) of ...
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Original Article Smooth muscle immaturity in the carotid arterial neointima as a prognostic marker for systemic atherogenic cardiovascular events in the Asian male
... the h-caldesmon/SMA ratio was associated with acute coronary syndrome in coronary arteries [14], this ratio did not differ significant- ly between symptomatic and asymptomatic patients. This may be due to a difference in ...
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Histological composition and progression of carotid plaque
... lular lipid core), V (fibroatheroma) and VI (complex plaque with possible surface defect, hemorrhage or thrombus) of AHA classification should be the only ones found in group I (symptomatic patients), but ...
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Alginate-chitosan Coated Lecithin Core Shell Nanoparticles for Curcumin: Effect of Surface Charge on Release Properties and Biological Activities
... loaded lipid core shell nanoparticles coated by primary chitosan and secondary sodium alginate layer availing sequential electrostatic interactions between lipid/polymer and then polymer/polymer ...
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A parameterized analysis of the mechanical stress for co ronary plaque fibrous caps
... plaque’s core is the fibrous cap, which is a layer of fibrous connective tissue and smooth muscle cells that prevents the core’s highly thrombogenic con- tents from coming into contact with ...soft lipid ...
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T1 Gadolinium Enhancement of Intracranial Atherosclerotic Plaques Associated with Symptomatic Ischemic Presentations
... Our study suggests that similar arterial wall pathology in ICAD may be the incit- ing factor for plaque progression and de- stabilization. Although neovasculariza- tion may be responsible for IPH as the result of rupture ...
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NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly
... Plasmids. The construction of plasmids containing the chimeric cDNAs pHJ3 (pH-NS2/NS3-J), pHJ3/QL (pH-NS2/NS3-J/QL), and pHJ2 (pH-(NS2)-J) has been described previously (51). pHJ2/QL and pJFH1/QL were constructed by ...
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Fluodot Nanoparticle – A Promising Novel Delivery System For Veterinary Vaccine
... Floudot is composed of a central protein core of bovine serum albumin (BSA) surrounded by a layer of organic diacid. One of the carboxyl groups of diacid covalently linked to one the many amine groups of BSA by ...
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The physiological, musculoskeletal and psychological effects of stand up paddle boarding
... A training study in which the aerobic and anaerobic cap- acity, blood lipid profile, body composition, isometric core strength, static and dynamic balance ability of a group of sedentary[r] ...
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Non invasive imaging of carotid arterial restenosis using 3T cardiovascular magnetic resonance
... This in vivo study identifies important differences in the nature of restenotic - as opposed to primary – carotid atherosclerotic plaques that have only previously been described in histological examination of explanted ...
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Biological differences between melancholic and nonmelancholic depression subtyped by the CORE measure
... across lipid oxidative stress markers (versus nonmelancholic patients) and immunological markers (versus both controls and nonmelancholic ...the CORE measure in this ...
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