Lipid nanocapsules
Stability evaluation of lipid nanocapsules in parenteral nutritional mixture
... nutrition. Lipid NanoCapsules based on vegetal oils (vo- LNC) can be used to allow both an easy dispersion of the oily phases in water and an improvement of parenteral mixture ...
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Fate of paclitaxel lipid nanocapsules in intestinal mucus in view of their oral delivery
... Abstract: The bioavailability of paclitaxel (Ptx) has previously been improved via its encapsu- lation in lipid nanocapsules (LNCs). In this work, the interactions between LNCs and intestinal mucus are ...
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Praziquantel–lipid nanocapsules: an oral nanotherapeutic with potential <em>Schistosoma mansoni</em> tegumental targeting
... Notes: Infected untreated group showing: (A) multiple granulomas of variable sizes and shapes with preserved hepatic architecture (×100); (B) cellular granuloma composed of lymphocytes, histiocytes, epithelioid cells, ...
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Synergistic interactions between antimicrobial peptides derived from plectasin and lipid nanocapsules containing monolaurin as a cosurfactant against <em>Staphylococcus aureus</em>
... Abstract: Development of effective antibacterial agents for the treatment of infections caused by Gram-positive bacteria resistant to existing antibiotics, such as methicillin-resistant Staphylococcus aureus (MRSA), is ...
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Targeting and treatment of glioblastomas with human mesenchymal stem cells carrying ferrociphenol lipid nanocapsules
... Abstract: Recently developed drug delivery nanosystems, such as lipid nanocapsules (LNCs), hold great promise for the treatment of glioblastomas (GBs). In this study, we used a sub- population of human ...
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Absence of lung fibrosis after a single pulmonary delivery of lipid nanocapsules in rats
... Abstract: Lipid nanocapsules (LNCs) are potential drug carriers for pulmonary delivery since they can be nebulized without any structural or functional changes, and the aerosols produced are highly ...
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Oral fondaparinux: use of lipid nanocapsules as nanocarriers and in vivo pharmacokinetic study
... using lipid-based nanoparticulate systems. This study examined lipid nanocapsules for their oral absorption potential as the first step in developing oral fondaparinux (Fp) novel ...cationic ...
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Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide
... (siRNA). Lipid nanocapsules (LNCs) covered by chitosan were developed in our laboratory by a transacylation ...resulting nanocapsules have a positive zeta potential that enables electrostatic ...
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Preparation and characterization of tetrandrine-phospholipid complex loaded lipid nanocapsules as potential oral carriers
... Methods: The phospholipid complex was prepared with the solvent-evaporation method to enhance the liposolubility of tetrandrine. The formation of the phospholipid complex was con- firmed with a solubility study, infrared ...
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Characterisation and Skin Distribution of Lecithin Based Coenzyme Q10 Loaded Lipid Nanocapsules
... Recently, lipid nanocapsules, a medium- chain triglyceride core surrounded by a membrane made from a mixture of lecithin and a PEGylated surfactant, were invented based on the above delivery carrier systems ...
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<p>Di-<em>O</em>-lauroyl-decitabine-lipid nanocapsules: toward extending decitabine activity</p>
... highest concentrations tested, whereas cell proliferation was significantly decreased by treatment with a free decitabine solution or decitabine (C12) 2 -loaded LNCs.. Moreover, the a[r] ...
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Reverse micelle-lipid nanocapsules: a novel strategy for drug delivery of the plectasin derivate AP138 antimicrobial peptide
... results, the MIC of 1–4 µ g/mL for AP138-RM-LNCs shows this formulation to be highly active against staphylococci. This study suggests that AP138-RM-LNCs may be a highly promising drug delivery system and acts a novel ...
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Magic Bullets - Nanocapsules in Future Medicine
... Gene therapy is an emerging technology that aims to permanently or temporarily correct a gene defect by the intracellular delivery of nucleic acids [38]. Gene defects can either arise during cell division processes or be ...
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Development and in vitro evaluations of new decitabine nanocarriers for the treatment of acute myeloid leukemia
... lation had a diameter of 26.5±0.5 nm, high encapsulation efficiency (85%), and a drug payload of 472±64 µg/mL. Decitabine-loaded THP-T80-LNC cytotoxicity was evaluated on two AML cell lines depending on their decitabine ...
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<em>Caenorhabditis elegans</em> as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage
... Eudragit nanocapsules are able to reduce lipid peroxidation in mouse brains and rat livers; thus, the encapsu- lation of melatonin improved the antioxidant properties of this ...
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“Nanocapsule” by Manali Pisal, Pranjal Barbade, Sayali C. Dudhal, India.
... application. Nanocapsules have efficient application in different field like agrochemicals, cosmetics products, genetic engineering technique, waste water treatment and cleaning ...cells. Nanocapsules can ...
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Biological evaluation of protein nanocapsules containing doxorubicin
... As a model drug delivery system, HspG41C–DOX cages were taken up by cells and DOX was released from HspG41C–DOX following cleav- age of the hydrazone bonds between HspG41C and DOX in [r] ...
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In vitro toxicity studies of biodegradable, polyelectrolyte nanocapsules
... -lysine–terminated nanocapsules (NC5), six-layer negatively charged PGA-terminated nanocapsules (NC6) and five-layer PEGylated nanocapsules ...polyelectrolyte nanocapsules tested for blood ...
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Photoresponsive nanocapsulation of cobra neurotoxin and enhancement of its central analgesic effects under red light
... nanocapsules is significantly enhanced by 650 nm irradia- tion. The central analgesic effect of CNT nanocapsules improves when the nasal cavity is irradiated by red light. The mechanism is related to ...
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Effect of O/W process parameters on Crataegus azarolus L nanocapsule properties
... the nanocapsules increases, the extract acts as a clog factor, causing an increase in the particle size and decreasing the stability ...the nanocapsules was measured by PSAR (Figure 6 and Table ...
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