Lipoteichoic acid
Innate immune responses induced by lipopolysaccharide and lipoteichoic acid in primary goat mammary epithelial cells
... Gram-positive lipoteichoic acid; LTF: Lactoferrin; MEC: Mammary epithelial cells; MYD88: Myeloid differentiation primary response 88; NFKB1: Nuclear factor of kappa light polypeptide gene enhancer in ...
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Streptococcus gordonii Type I Lipoteichoic Acid Contributes to Surface Protein Biogenesis
... IMPORTANCE Discovered over a half-century ago, lipoteichoic acid (LTA) is an abun- dant polymer found on the surface of Gram-positive bacteria. Although LTA is essen- tial for the survival of many ...
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Lipoteichoic Acid Inhibits Interleukin-2 (IL-2) Function by Direct Binding to IL-2
... Lipoteichoic acid (LTA) is associated with the cell envelope of most gram-positive bacteria. Although previously thought to act mainly as a virulence factor by virtue of its adhesive nature, evidence is now ...
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R-roscovitine Reduces Lung Inflammation Induced by Lipoteichoic Acid and Streptococcus pneumoniae
... Bacterial pneumonia remains associated with high morbidity and mortality. The gram-positive pathogen Streptococcus pneu- moniae is the most common cause of community-acquired pneumonia. Lipoteichoic acid ...
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Lipoteichoic Acid Synergizes with Glycosphingolipids To Potently Stimulate Secretion of Interleukin-6 from Human Blood Cells
... It has been established that septic shock caused by gram- negative pathogens is primarily due to the ability of lipopoly- saccharide (LPS) to trigger the excessive secretion of proin- flammatory cytokines by macrophages ...
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Lipoteichoic acid is an important microbe-associated molecular pattern of Lactobacillus rhamnosus GG
... Many MAMPs are surface located molecules, such as lipopolysaccharides interacting with TLR4/MD2 and fla- gellin interacting with TLR5. Lipoteichoic acid (LTA) is a widely studied MAMP of the low G+C ...
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Staphylococcal lipoteichoic acid inhibits delayed type hypersensitivity reactions via the platelet activating factor receptor
... Staphylococcus aureus infections are known triggers for skin inflammation and can modulate immune responses. The present studies used model systems consisting of platelet-activating factor receptor–positive and –negative ...
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The immunomodulatory role of lipoteichoic acid from probiotic bacteria : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry, Institute of Molecular BioSciences, Massey University, Palmerston North, New Zealand
... I lipoteichoic acid, consisting of a polymer of glycerol-phosphate linked to a glycolipid anchor, based on comparison with published NMR studies of LTA (Morath et ...
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The immune evasion protein Sbi of Staphylococcus aureus occurs both extracellularly and anchored to the cell envelope by binding lipoteichoic acid.
... component. Lipoteichoic acid (LTA) is an anionic polymer linked to a glycolipid anchor in the outer face of the cytoplasmic membrane and with a poly(g- lycerophosphate) chain that extends across the cell ...
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Original Article Lipoteichoic acid of Streptococcus sanguinis induces the expression of cyclooxygenase-2 via MAPK signaling pathways in H9c2 cells
... endocarditis. Lipoteichoic acid, is a component of the outer membrane of Gram-positive bacte- ria and can cause septic ...to lipoteichoic acid in order to determine levels of nuclear factor ...
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Experimentally induced subclinical mastitis: are lipopolysaccharide and lipoteichoic acid eliciting similar pain responses?
... nents, lipoteichoic acid (LTA) and lipopolysaccharide (LPS), deriving from Staphylococcus aureus and Escheri- chia coli respectively, are commonly infused in the bovine mammary gland to elicit experimental ...
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The Cell Wall Polymer Lipoteichoic Acid Becomes Nonessential in Staphylococcus aureus Cells Lacking the ClpX Chaperone
... ABSTRACT Lipoteichoic acid (LTA) is an important cell wall component of Gram-positive bacteria and a promising target for the development of vaccines and antimicrobial compounds against Staphylococcus ...
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Lipoteichoic acid induces surfactant protein-A biosynthesis in human alveolar type II epithelial cells through activating the MEK1/2-ERK1/2-NF-κB pathway
... Figure 4 Effects of lipoteichoic acid (LTA) on translocation of the transcription factor, nuclear factor (NF)- κ B, from the cytoplasm to nuclei. A549 cells were exposed to 30 μ g/ml LTA for 1, 6, and 24 h. ...
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β-lactam antibiotic-induced release of lipoteichoic acid from Staphylococcus aureus leads to activation of neutrophil granulocytes
... peptidoglycan which covers a thin cytoplasmic mem- brane. Several compounds such as teichoic acid, lipogly- cans, polysaccharides and lipoteichoic acid (LTA) are incorporated in the peptidoglycan ...
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Platelet-Activating Factor-Acetylhydrolase Can Monodeacylate and Inactivate Lipoteichoic Acid
... A major component of the cell walls of gram-positive bac- teria is lipoteichoic acid (LTA), which is a polyphosphate poly- mer linked to a glycerol backbone with two acyl chains. The acyl chains anchor the ...
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Circulating microRNA signatures in mice exposed to lipoteichoic acid
... Early diagnosis of bacterial infection is critical for pre- venting further complications. Pathological processes after bacterial infection are mainly induced by structural com- ponents of bacterial cell walls [11]; In ...
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Antibodies to staphylococcal peptidoglycan and its peptide epitopes, teichoic acid, and lipoteichoic acid in sera from blood donors and patients with staphylococcal infections
... teichoic acid, and lipoteichoic acid, as well Antibodies to the staphylococcal antigens peptidoglycan, as to the peptidoglycan epitopes L-Lys-D-Ala-D-Ala, L-Lys-D-Ala, and pentaglycine, [r] ...
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Induction of intestinal pro-inflammatory immune responses by lipoteichoic acid
... of the gut is L. acidophilus, which expresses unique sur- face layer proteins (Slps), including A, B, X, and abun- dant lipoteichoic acid (LTA). LTA is a zwitterionic glycolipid found in the cell wall of ...
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Anti-inflammatory and anti-oxidant mechanisms of an MMP-8 inhibitor in lipoteichoic acid-stimulated rat primary astrocytes: involvement of NF-κB, Nrf2, and PPAR-γ signaling pathways
... Background: Recent evidence suggests that reactive astrocytes play an important role in neuroinflammation and neurodegenerative diseases. Thus, controlling astrocyte reactivity has been suggested as a promising strategy ...
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Peptidoglycan and Lipoteichoic Acid Modify Monocyte Phenotype in Human Whole Blood
... and lipoteichoic acid (LTA), compared to lipopolysaccharide (LPS), on the monocyte expression of receptors involved in antigen presentation (HLA-DR, ...
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