Lipoxygenase Activity
Augmentation of 5 lipoxygenase activity and expression during dengue serotype 2 infection
... with DENV using electrophoresis on SDS gel and subse- quent Western blot analysis. Proteins were isolated by sus- pending neutrophils in RIPA buffer containing protease inhibitor P8340 (20 μL/ mL of RIPA-buffer) for 30 ...
9
ANTIOXIDANT ACTIVITY AND INHIBITION OF LIPOXYGENASE ACTIVITY ETHANOL EXTRACT OF ENDOSPERM ARENGA PINNATA (WURMB) MERR
... The results are shown in Fig. 5 reveal that 0.2N HCl cannot resist the formation of the product, as indicated by its falling and rising curves. The results for 1N and 2N HCl also reveal that they cannot resist the course ...
5
Lipoxygenase activity in ontogenesis of ferns Salvinia natans and Polystichum aculeatum
... LOX activity distribution ...LOX activity in fronds increased, reaching its maximum in the sporiferous phase that, as we think, is due to active metabolic processes during spore maturation ...
8
Effects of inoculation by arbuscular mycorrhizal fungi on the composition of the essential oil, plant growth, and lipoxygenase activity of Piper aduncum L.
... colonization, lipoxygenase (LOX) activity, and essential oil (OE) chemical composition were moni- tored at 30, 60 and 90 days’ post-inoculation ...LOX activity had an increase in the leaves and roots ...
12
PHYTOCHEMICAL ANALYSIS AND ANTI-INFLAMMATORY ACTIVITY OF MEDICINAL PLANT AQUEOUS AND ETHANOLIC EXTRACT OF BOERHAAVIA DIFFUSA LEAVES EXTRACTS
... inhibitory action. Heat induced haemolysis of erythrocyte was significantly 50% of inhibited atthe concentration of 300.47±2.57 and 238.97±2.03 μg/ml for aqueous and ethanol extract, respectively. Hypotonicity induced ...
13
Chitosan enhances rosmarinic acid production in shoot cultures of Melissa officinalis L. through the induction of methyl jasmonate
... much activity in the phenyl- propanoid pathway and the tyrosine-derived pathway was able to produce more rosmarinic ...in lipoxygenase activity and OPR3 gene upregulation, which was associated with ...
10
Design of ionic liquid-based microwave-assisted extraction of flavonoids from Cyclea barbata Miers. and its lipoxygenase inhibitory activity
... The LIA assay was conducted using baicalein as a standard (Putri et al., 2017). Baicalein is a flavonoid from flavonols groups (Kusmardiyani et al., 2014) that has the capability to inhibit the lipoxygenase ...
7
Purification and properties of lipoxygenase from wheat seedlings infected by Fusarium graminearum and treated by salicylic acid
... studied lipoxygenase activity in the control plants, those infected by Fusarium graminea- rum, treated by SA in wheat genotypes distinguished by the level of resistance to fusariosis ...enzyme ...
9
Activity of the lipoxygenase inhibitor 1-phenyl-3-pyrazolidinone (phenidone) and derivatives on the inhibition of adhesion molecule expression on human umbilical vascular endothelial cells
... combined lipoxygenase and cyclo- oxygenase inhibitors (Hlasta et al ...include lipoxygenase inhibition, cyclooxygenase inhibition, antioxydative effects, or a combination of the ...potent ...
10
Role of oxidized low density lipoprotein in atherogenesis
... However, 15-lipoxygenase activity in cultured endothelial and smooth muscle cells appears to play a dominant role in the ability of these cells to oxidatively modify LDL 10, and recent d[r] ...
9
Disruption of the 12/15 lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice
... L-12LO gene was apparently sufficient to yield similar lesion size in mice expressing 2 copies of the L-12LO gene on an apo E–deficient background, indicating no gene dosage effects. These lesion data are even more ...
9
A RARE AND SEVERE ICHTHYOSIS OF NEONATES -HARLEQUIN ICHTHYOSIS
... ABCA12, lipoxygenase-3, 12R-lipoxygenase, CYP4F22, ichthyin and stero- id sulfatase, all of which are thought to be related to the intercellular lipid ...
8
Genetic variation in the leukotriene pathway is associated with myocardial infarction in the Chinese population
... 5- lipoxygenase-activating protein) and LTA4H (leukotriene A4 hydrolase) has previously been shown to contribute to the risk of MI (myocardial infarction) in Caucasian and African American ...
9
Systems pharmacology based approach to investigate the in vivo therapeutic efficacy of Albizia lebbeck (L ) in experimental model of Parkinson’s disease
... [58]. A study has suggested the degeneration of seroto- nergic terminals is an early process in the pathogenesis of PD and with preferential lower rate of degeneration as compare of dopaminergic neurons [59]. The ...
16
Antioxidant and anticancer activities of polyphenolic compounds from three Acanthaceae medicinal species from Burkina Faso
... ABTS (73.37μ4.15) activities and a best reducing abilities (1.46μ0.02); suggesting his wealth in antioxidant compounds. The active compounds could be a polyphenolic one because this extract has presented best phenolic, ...
6
Quantitative structure activity relationship study of inhibitory activities of 5-lipoxygenase and design new compounds by different chemometrics methods
... inhibitory activity of 1-phenyl[2H]-tetrahydro-triazine-3-one analogues as inhibitors of ...inhibitory activity of compounds which were not in the modeling ...inhibitory activity of the new inhibitor ...
13
The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5 lipoxygenase activating protein
... phatase activity and osteocalcin release. Alkaline phosphatase activity was determined on cell aliquots by substrate hydrolysis with p-nitrophenyl phosphate, and osteocalcin release was determined in cell ...
10
In vitro Evaluation of Antiproliferative, Lipoxygenase and Xanthine Oxidase Inhibitory Activities of Artemisia nilagirica (C.B.Clarke) Pamp. Leaf Extracts
... To conclude, ANM exhibited cytotoxic activity against human breast cancer cells. The extracts also inhibited the enzymes LOX and XO in a concentration- dependent manner. The findings of this study warrant future ...
7
Free radical scavenging activity and lipoxygenase inhibition of Mahonia aquifolium extract and isoquinoline alkaloids
... BBIQ alkaloids, such as berbamine, oxyacanthine, tetran- drine, have been reported to inhibit platelet activation, histamine release, superoxide generation by polymorpho- nuclear leucocytes (PMNL), lipid peroxidation in ...
7
Expression of 5 lipoxygenase and 15 lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids
... 15-Lipoxygenase (15-LO) is a lipid-peroxidizing enzyme mainly expressed in airway epithelial cells, eosinophils, reticulocytes and macrophages. In humans, 15-LO exists as two different enzymes with different cell ...
11