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Liver Cancer

Effects of siRNA targeting BMPR-II on the biological activities of human liver cancer cells and its mechanism

Effects of siRNA targeting BMPR-II on the biological activities of human liver cancer cells and its mechanism

... Bone morphogenetic proteins (BMPs), a member of transforming growth factor beta (TGF-β) family [1], are involved in cell proliferation, migration, differentiation and apoptosis [2]. Neovascularization is important for ...

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Prioritizing strategies for comprehensive liver cancer control in Asia: a conjoint analysis

Prioritizing strategies for comprehensive liver cancer control in Asia: a conjoint analysis

... Most Asian governments have implemented policies and laws to prevent Hepatitis B Virus (HBV) and Hepa- titis C Virus (HCV) infection, seeking to control HCC by targeting important risk factors. Universal hepatitis B ...

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Original Article Decreased serum miR-375 and miR-320a levels are useful in predicting liver cancer

Original Article Decreased serum miR-375 and miR-320a levels are useful in predicting liver cancer

... of liver cancer was ...of liver cancer was ...of liver cancer was significant- ly higher than that of miR-375 and miR- ...to liver function damage, provides valu- able ...

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Original Article miRNA-101 affecting proliferation and invasion of liver cancer by down-regulating COX-2 expression

Original Article miRNA-101 affecting proliferation and invasion of liver cancer by down-regulating COX-2 expression

... the liver cancer tissues and cells, and in vitro prolif- eration and invasion of liver cancer cells over- expressing miR-101 decreases ...of liver cancer by regulat- ing the ...

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Immune checkpoint therapy in liver cancer

Immune checkpoint therapy in liver cancer

... lung cancer in 2015 in the United States, European Union, and ...with liver cancer, including hepatocellular carcinoma and cholangiocarcinoma, two main primary liver ...

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Liver Cancer Detection

Liver Cancer Detection

... Machine learning techniques play an important role in building predictive models by learning from Electronic Health Records (EHR). Predictive models building from Electronic Health Records still remains as a challenge as ...

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The association of liver function and quality of life of patients with liver cancer

The association of liver function and quality of life of patients with liver cancer

... Liver cancer ranked the fifth most common cancer in the world, with 782,451 new cases per year in ...of cancer death world- wide, responsible for 745,533 deaths in ...chronic liver dis- ...

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Cancer stem cells in the development of liver cancer

Cancer stem cells in the development of liver cancer

... and liver cancer ...and liver CSC development and maintenance. Recently, liver CSCs were observed in Myc-driven but not Akt/Ras-driven tumors, suggesting a role for Myc in liver CSC ...

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Analysis of Spatial Epidemic Characteristics of Liver Cancer in Small Geographical Area

Analysis of Spatial Epidemic Characteristics of Liver Cancer in Small Geographical Area

... 1.88 and the log likelihood ratio 30.86, while the second gathering area is mainly located in the west coast of Longkou City, including 151 villages, with the relative risk 1.43 and the logarithmic likelihood ratio ...

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Steatosis and liver cancer in transgenic mice.pdf

Steatosis and liver cancer in transgenic mice.pdf

... a liver-specific ...of liver cancer in older male FL-N/35 mice, arise as a direct result of the expression of viral ...and liver cancer in humans with chronic hepatitis ...

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Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress

Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress

... during liver patho- genesis and injury that impinge on its normal metabolic functions in behalf of the ...the liver imparted by the ...to liver stress caused by not only metabolic extremes, but also ...

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Title:  ANTIDIABETIC AND ANTIOXIDANT ACTIVITY OF AQUEOUS ROOT EXTRACT OF CHLOROPHYTUM BORIVILIUANUM (SAFED MUSLI) Author:  Hemlata Rathore, Bhushan Hatwar & Shishupal Bodhankar Keyword:  Chlorophytum boriviliuanum, Antidiabetic & AntioxidantPage No:  37-4

Title: ANTIDIABETIC AND ANTIOXIDANT ACTIVITY OF AQUEOUS ROOT EXTRACT OF CHLOROPHYTUM BORIVILIUANUM (SAFED MUSLI) Author: Hemlata Rathore, Bhushan Hatwar & Shishupal Bodhankar Keyword: Chlorophytum boriviliuanum, Antidiabetic & AntioxidantPage No: 37-43DOI: 10.30876/JOHR.8.3.2019.37-43Abstract: Objective: To investigate the antidiabetic effect of aqueous extract of Chlorophytum borivilianum (safed musli) root. Methods: The collected roots were washed; shade dried and was pulverized with a me chanical pulverizer for the size reduction. It was then passed through mesh of size # 60 and the fine powder was collected and was used for the experiment for powder microscopy and preparation of extract. The root powder (1000 g) was subjected to cold maceration in 2 L of sterile distilled water for 48 hours at room temperature, filtered into a clean round bottom flask. The a- Glucosidase inhibitory activity was conducted where 100µl of a sample of different concentrations was incubated with 50µl a-glucosidase (1.0 U/ml) (from Saccharomyces cerevisiae) in phosphate buffer (0.1 M, pH 6.8) for 10 min at 37°C. The reaction was initiated by addition of 50 µl of substrate: 5 mM, p-nitrophenyl-a-D glucopyranoside in a 0.1 M phosphate buffer at pH 6.8. P-nitrophenol’s release kinetics. The a -Amylase Inhibition where 250µL of the extract (5mg/mL) was preincubated with 250µL of -amylase solution for 10min at 25°C in one set of tubes. In another set of tubes -amylase was preincubated with 250µL of phosphate buffer (pH 6.9). 250µL of starch solution at increasing concentrations (0.30–5.0mg/mL) was added to both sets of reaction mixtures to start the reaction. The mixture was then incubated for 10min at 25°C and then boiled for 5min after the addition of 500µL of DNS to stop the reaction. Results: In this study acarbose was also used as a standard drug for a-glucosidase inhibitor. Acarbose at a concentration of (100-1000 µg/ml) showed a-glucosidase inhibitory activity from 30. 31±0.1084to 84.05±0.2075% with an IC value 411.436567µg dry extract, & acarbose was also used as a standard drug for a amylase inhibitor. Acarbose at a concentration of (100-1000 µg/ml) showed a-glucosidase inhibitory activity from 23.33±0.1415 to 62.05±0.2725% with an IC value 236.774194µg dry extract. Conclusions: As a result, we found that the extract of C. boriviliamum have free radical scavenging activity and inhibitory activity against a-amylase and a-glucosidase and this therapeutic potentiality could be exploited in the management of post prandial hyperglycemia in the treatment of type 2 diabetes mellitus. Download PDF

... of liver: The liver is the largest gland in the ...epigastrium. Liver lobes and lobules: The liver consists of two lobes separated by the falciform ...the liver, and the right lobe ...

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Original Article Clinicopathological features of primary hepatic diffuse large B-cell lymphoma: a report of seven cases and a literature review

Original Article Clinicopathological features of primary hepatic diffuse large B-cell lymphoma: a report of seven cases and a literature review

... the liver, with a cross-sectional area of ...count. Liver function test revealed higher than normal levels of alkaline phospha- ...mary liver cancer in four cases, primary liver ...

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High prevalence of Pentatrichomonas hominis infection in gastrointestinal cancer patients

High prevalence of Pentatrichomonas hominis infection in gastrointestinal cancer patients

... It is well-known that P. hominis mainly colonizes the large intestine in humans [23, 27]. How P. hominis infec- tions influence other gastrointestinal cancers is elusive. Although unlikely, it is possible that P. hominis ...

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Folklore medicinal plants used in liver disease: A review

Folklore medicinal plants used in liver disease: A review

... terms liver cancer, medicinal plants, liver disorder and medicinal plants, liver disease and medicinal plants, effect of extract and essential oil of effective medicinal plants on liver ...

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Cancer risk after renal transplantation in South Korea: a nationwide population-based study

Cancer risk after renal transplantation in South Korea: a nationwide population-based study

... Lung cancer was confirmed in six patients (five males, one female) in this ...lung cancer is as- sociated with smoking, RTRs should be strongly encour- aged to quit smoking, and screening with low-dose CT ...

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EuropePMC-PMC5347641.pdf

EuropePMC-PMC5347641.pdf

... Alcoholic liver disease (ALD) is a leading cause of cirrhosis, liver cancer, and acute and chronic liver failure and as such causes significant morbidity and ...significant liver ...

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Original Article Central venous-to-arterial partial pressure of carbon dioxide difference indicates the prognosis of cancer patients with sepsis

Original Article Central venous-to-arterial partial pressure of carbon dioxide difference indicates the prognosis of cancer patients with sepsis

... lung cancer, 7 for esophageal cancer, 7 for gas- tric cancer, 2 for colorectal cancer, 1 for liver cancer, 6 for pancreatic cancer, 2 for gallblad- der cancer, 2 ...

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Pharmacognostic, Phytochemical and Pharmacological Evaluation on the Leaves of Ipomoea Pes-Tigridis Linn. Convolvulaceae

Pharmacognostic, Phytochemical and Pharmacological Evaluation on the Leaves of Ipomoea Pes-Tigridis Linn. Convolvulaceae

... using the regression analysis and was found to be155.2µg/mL which is shown in Fig. 25. The 70% ethanolic extract of Ipomoea pes-tigridis was studied for their in vitro effects on liver HEPG2 cell lines. The ...

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Association of Positive Results of Single Serum
Biomarker with the Clinical Parameters

Association of Positive Results of Single Serum Biomarker with the Clinical Parameters

... lung cancer could cause the high level of ...breast cancer. In addition to breast cancer, there were other diseases such as ovarian cancer, lung cancer, cirrhosis, lung infection, ...

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