liver injury
Original Article BML-111 ameliorates endotoxin-induced liver injury through increasing prostaglandin J
... LPS-induced liver inflammatory pro- cess tightly is regulated by not only pro-inflam- matory mediators that initiate and exacerbate inflammation but also anti-inflammatory media- tors that switch off and resolute ...
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Antipsychotic Drugs and Liver Injury
... the liver and was often dose- dependent, usually predictable, and also called intrinsic ...other liver injury mechanisms such as immunity and inflammatory ...
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Risk of acute and serious liver injury associated to nimesulide and other NSAIDs: data from drug-induced liver injury case-control study in Italy
... determine liver injury, a low alpha-1-antitrypsin level and an abnormal phenotype (that may suggest disease associated with a de fi ciency of this protein), Wilson’s disease, HIV/AIDS, hepatic neoplasia or ...
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Liver injury in α1 antitrypsin deficiency: an aggregated protein induces mitochondrial injury
... of liver disease among ...significant liver disease over the first 20 years of life (11, ...to liver injury. Because only a subgroup of homozygotes develop liver disease and because ...
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Original Article Kidney and lung tissue modifications after BDL-induced liver injury in mice are associated with increased expression of IGFBPrP1 and activation of the NF-κB inflammation pathway
... whether liver injury by bile duct ligation (BDL) causes modifications in kidney and lung tissue in mice, and to explore the possible mechanism of these ...of liver, kidney, and lung tissue were ob- ...
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Advances in Bile Acids-Mediated Liver Injury and Liver Regeneration
... the liver through different pathways as is shown in Table ...on liver but also a mild increase of BAs administration may raise liver regeneration through several ...both liver injury ...
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Molecular mediators of hepatic steatosis and liver injury
... According to the two-hit hypothesis, hepatic steatosis is a prereq- uisite for subsequent events that lead to liver injury (5). Despite the high prevalence of NAFLD and its potential for serious sequelae, ...
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CME Article : Computed Tomography (CT) in Blunt Liver Injury : A Pictorial Essay
... patients, liver is one of the commonest organs being injured and CT can accurately identify and assess the extent of the ...blunt liver trauma include laceration, subcapsular or parenchymal haematomas, ...
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-induced acute liver injury in mice
... relative liver weight and the histopathology of the ...in liver were significantly ...in liver significantly were increased, while the content of malondialdehyde (MDA) was significantly decreased by ...
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Original Article Liver protein spectrum in a rat liver injury model
... drug-induced liver injury (DILI) is a common event because of the expanding use of prescription drugs, accounting for about 13% of acute liver failure cases in the United States ...to liver ...
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Drug-induced liver injury due to varenicline: a case report
... hepatic injury, risk factors, concomitant drug use, evaluation for other etiologies of liver injury, pre- existing data regarding the hepatotoxic potential of the sus- pected drug, and response of ...
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Levothyroxine induced liver injury followed by complete recovery upon cessation of the drug: a case report
... Levothyroxine-induced liver injury is a rare and revers- ible adverse ...as liver biopsy were not required to support the diagnosis in our patient ’ s ...causes liver injury require ...
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Is there a place for sevoflurane to prevent liver ischemia-reperfusion injury during liver transplantation?
... IR injury in other situations than heart ischemia, such as cerebral [17], intestinal [18], renal [19] and liver ischemia ...of liver transplantation (LT) and surgery, several strategies have been ...
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LYVE1 and PROX1 in the reconstruction of hepatic sinusoids after partial hepatectomy in mice
... to liver sinusoidal endothelial cells, they share simi- larities with lymphatic endothelial cells in function and phenotype ...LYVE1-positive liver sinusoidal endothelial ...
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Hepatotoxicity of tocilizumab and anakinra in rheumatoid arthritis: management decisions
... toxic liver effects. Liver biopsy in both cases showed focal necrosis of hepatocytes – a hallmark of drug toxicity – with steatosis and early ...for liver injury were ...the liver ...
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Liver Response to Indomethacin-Induced Intestinal Injury
... intestinal injury on the ...the liver was decreased as documented by signi- ficantly diminished serum concentration of albumin in indomethacin treated ...the liver. The decreased functional capacity ...
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Original Article Different doses of partial liver irradiation promotes hepatic regeneration in rat
... gan, liver. In-depth stu- dy on liver regenera- tion after hepatectomy is helpful for the liver function recovery of patients with acute or chronic liver failure and the reduction of overall ...
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Clinical spectrum and therapeutic approach to hepatocellular injury in patients with hyperthyroidism
... Abstract: Liver dysfunction in patients with hyperthyroidism includes abnormalities associated with the effects of thyroid hormone excess, those secondary to drug-induced liver injury, and changes ...
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Sertraline Induced Acute Hepatitis: A Case Report
... Christopher F describe that in rare instances of acute clinically apparent episodes of liver injury with marked liver enzyme elevations with or without jaundice been reported in patients on ...
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Paeoniflorin regulates macrophage activation in dimethylnitrosamine induced liver fibrosis in rats
... Liver injury could be associated with macrophage ac- tivation and trigger migration of macrophages into hep- atic cords in which they stimulate fibrosis by secreting proinflammatory ...fact, liver ...
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