Liver iron
Estimation and quantification of liver iron concentration by magnetic resonance imaging
... measuring liver iron content (LIC) in a variety of ...of liver iron content provides prognostic information regarding the risk for developing complications such as hepatic fibrosis and ...HH, ...
6
IDEAL-IQ in an oncologic population: meeting the challenge of concomitant liver fat and liver iron
... normal liver iron, mildly ele- vated liver iron, moderately elevated liver iron, severely elevated liver ...and liver-iron-concentration ...to iron ...
7
Hepcidin levels correlate to liver iron content, but not steatohepatitis, in non-alcoholic fatty liver disease
... fatty liver disease (NAFLD) develop dysmetabolic iron overload syndrome (DIOS), the pathogenesis of which is ...the iron-regulatory peptide hepcidin has been reported in NAFLD, but it is unclear if ...
10
HIF 2α, but not HIF 1α, promotes iron absorption in mice
... of iron absorption in the intestine, is hypoxic and generated conditional knockout mice that lacked either Hif1a or Hif2a specifically in the intestinal ...for iron absorption, whereas HIF-2a played a ...
9
Quantification of iron concentration in the liver by MRI
... Indirect markers have been identified, such as serum ferritin and transferrin saturation, and these are sensitive but are not specific [3]. Further, the diagnosis of primary haemochromatosis has improved since various ...
8
Assessment of Organ Specific Iron Overload in Transfusion-dependent Thalassemia by Magnetic Resonance Imaging Techniques
... is iron overload in different ...for iron detection in various tissues, hence the introduction of MRI has revolutionized the management of these patients and improved the life expectancy of ...patients. ...
8
Iron Overload in Children Who Are Treated for Acute Lymphoblastic Leukemia Estimated by Liver Siderosis and Serum Iron Parameters
... control liver biopsies but instead evaluated the resolution of iron overload by moni- toring the values of serum iron parameters, espe- cially ...body iron load. The evaluation of iron ...
8
The effect of feeding a low iron diet prior to and during gestation on fetal and maternal iron homeostasis in two strains of rat
... fetal iron trans- fer in the RHL rats, despite a reduction in placental weight in response to low iron diet in this strain ...tal iron transporters in this ...of iron to the fetus at the ...
9
The Influence of Repeated Blood Withdrawals before Surgery on Clinical Outcome
... USA). Liver tis- sue for a histopathological examination was obtained from standard ...for iron by potassium ferrocyanide (PENTA, Hradec Kralove, CZ). The liver iron content was evaluated ...
5
Glycoside rich fraction from Spondias pinnata bark ameliorate iron overload induced oxidative stress and hepatic damage in Swiss albino mice
... and iron chelation activity of the fraction leads us to test the sample for it’s in vivo iron chelation as well as hepato-ameliorating activity in Swiss albino ...that iron in excess, induced hepatic ...
12
MRI evaluation of hepatic and cardiac iron burden in pediatric thalassemia major patients: spectrum of findings by T2*
... and liver iron loading ...heart iron content based on T2* ...between liver and heart T2* and levels of serum ferritin in TM patients and he reported a cor- relation between serum ferritin ...
9
Molecular and cellular aspects of iron induced hepatic cirrhosis in rodents
... In iron-dosed gerbils on the vitamin E-enriched diet for 4 mo, in spite of a severe liver iron burden, a normal lobular architecture was found, with a dramatic decrease of collagen mRNA accumulation ...
9
Early Cardiac Iron Overload in a Child on Treatment of Acute Lymphoblastic Leukemia
... abnormal liver with surface nodularity and multiple, ill-defined, hypodense ...lesions. Liver biopsy demonstrated severe iron ...elemental iron. At the time of liver biopsy, his ...
6
Iron bioavailability from a tropical leafy vegetable in anaemic mice
... Iron deficiency anaemia is a nutritional disorder afflicting large population groups in the world. It is prevalent amongst vulnerable infants, adolescent girls and pregnant women particularly in populations ...
7
Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver
... transmembrane iron transporter known to be involved in cellular iron ...intestinal iron absorption, erythroid iron utilization, hepatic iron accumulation, placental iron ...
10
The Digestive Utilization of Iron and Copper in the Fattening Swine Organism
... of iron and copper in both phases of fattening, it has been established the biggest amount of microelements from blood, liver, fat and ...of iron and copper radioactivity in the experimental period ...
5
Stimulating Effect of Red Beetroot (Beta vulgaris) Juice, Fractioned by Membrane Ultrafiltration, on Iron Absorption in Chicken Intestines
... stimulate iron assimilation in humans are targeted on food fortification with iron-containing substances or on iron bioavailability ...of iron and ferritin, which increases iron ...
13
A mouse model of juvenile hemochromatosis
... cm from the pylorus, which is shown on the right in A and B. Staining is most intense proximally in the wild-type animals but is expressed more intensely and along the distal two-thirds of the villus in the mutant ...
6
Efficient clearance of non transferrin bound iron by rat liver Implications for hepatic iron loading in iron overload states
... most iron had been removed by parenchymal ...ferric iron (apparent Km, 14-22 microM; V max, 24-38 nmol min-1 g ...non-transferrin-bound iron in plasma may be an important cause of hepatic iron ...
9
Study of Magnesium, Copper, Zinc, Iron and Ceruloplasmin in Liver Cirrhosis and Ovarian Cancer Ascitic Patients
... the liver directly or indirectly through Kuppfer cells stimulations ...ferrous iron to ferric ...etc. Iron is essential to most living organisms and participates in a variety of vital processes ...
10