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liver steatosis

A simple index of lipid overaccumulation is a good marker of liver steatosis

A simple index of lipid overaccumulation is a good marker of liver steatosis

... lnLAP and showed an independent effect of sex but not of age on liver steatosis. Model 3 removed the non-sig- nificant age term from Model 2 and offered “strong evidence” of improvement as compared to Model ...

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Brown fat activation mitigates alcohol induced liver steatosis and injury in mice

Brown fat activation mitigates alcohol induced liver steatosis and injury in mice

... alcoholic liver disease ...the liver to induce steatosis ...worsening liver steatosis ...in liver injury and inflammation ...increasing liver damage risk (11, ...fatty ...

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Original Article Diagnostic accuracy of magnetic resonance imaging-proton density fat fraction in quantifying liver steatosis: a systematic review and meta-analysis

Original Article Diagnostic accuracy of magnetic resonance imaging-proton density fat fraction in quantifying liver steatosis: a systematic review and meta-analysis

... atosis in different studies, so we divided the nearby cut-off values into one grade based on to NASH nonalcoholic steatohepatitis CRN Cl- inical Research Network scoring system. The ideal situation would be to analyze ...

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Metabolic profiles and liver steatosis in children with liver transplantation for progressive familial intrahepatic cholestasis type 1

Metabolic profiles and liver steatosis in children with liver transplantation for progressive familial intrahepatic cholestasis type 1

... cholestatic liver disease leading to portal hypertension, cirrhosis and liver ...orthotopic liver transplantation during childhood [1, 2, 8–10]. Severe liver steatosis is a common ...

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Genome-WideAnalysisof DNACopy NumberChangesinLiverSteatosis

Genome-Wide Analysis of DNA Copy Number Changes in Liver Steatosis

... Liver steatosis is the most common benign form of non-alcoholic fatty liver disease ...(i.e., steatosis) is the hallmark of ...which steatosis is accompanied by liver ...

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Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα

Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα

... different roles of 2 JNKs in hepatic lipid metabolism (42). Our results indicate that hepatic periostin overproduction phe- nocopies PPARα deficiency with respect to TG levels, and loss of PPARα was sufficient to ...

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Increased serum levels of lipogenic enzymes in patients with severe liver steatosis

Increased serum levels of lipogenic enzymes in patients with severe liver steatosis

... The state of over-nutrition-induced insulin resistance and decreased de novo lipogenesis have been demon- strated to be associated with increased FAS in serum [2,25]. Circulating FAS levels of obese individuals could be ...

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Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism

Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism

... fatty liver development in animal models of obesity ...improved liver steatosis ...correct liver steatosis and even NASH when it already has developed, has not yet been ...

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In vitro assessment of nutraceutical compounds and novel nutraceutical formulations in a liver-steatosis-based model

In vitro assessment of nutraceutical compounds and novel nutraceutical formulations in a liver-steatosis-based model

... function and glucose metabolism [15]. Because of the better performance demonstrated by combinations/mix- tures of different compounds compared to the single- molecules-based products, new formulations are going to be ...

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Non-contrasted computed tomography for the accurate measurement of liver steatosis in non alcoholic fatty liver disease.

Non-contrasted computed tomography for the accurate measurement of liver steatosis in non alcoholic fatty liver disease.

... we can accurately predict the presence of NAFLD. It could served as a quantitative assessment of NAFLD score. The control arm was not designed due to the ethical point of view as well as risk of liver biopsy in ...

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Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study

Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study

... Results: Histopathology of liver biopsies showed steatosis in 30 of 44 (68%) patients. FibroMax results were positively correlated with viral load by quantitative polymerase chain reaction and ...

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Plasmatic higher levels of homocysteine in Non-alcoholic fatty liver disease (NAFLD)

Plasmatic higher levels of homocysteine in Non-alcoholic fatty liver disease (NAFLD)

... fatty liver disease (NAFLD) is a chronic liver disease, which includes a spectrum of hepatic pathology such as simple steatosis, steatohepatitis, fibrosis and ...between liver steatosis ...

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Liver surgery in the presence of cirrhosis or steatosis: Is morbidity increased?

Liver surgery in the presence of cirrhosis or steatosis: Is morbidity increased?

... that steatosis was a predictor of postoperative complica- tions, but mainly due to minor ...of liver steatosis or other histological features such as steato- hepatitis or ...of steatosis in ...

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Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis

Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis

... Nor can the increased hepatic TAG associated with the variant allele be due to an increase in the normal enzyme activity, since we did not observe any increase in hepatic TAG in the mice expressing very high levels of ...

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Diagnostic performance of gadoxetic acid–enhanced liver MRI versus multidetector CT in the assessment of colorectal liver metastases compared to hepatic resection

Diagnostic performance of gadoxetic acid–enhanced liver MRI versus multidetector CT in the assessment of colorectal liver metastases compared to hepatic resection

... sequences can detect it. In this setting, also, EOB-GD contrast not allow to increase the diagnostic perform- ance since the lesion is extraparenchimal. At the end, we evaluated the diagnostic performance of MDCT and MRI ...

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Dietary soy protein induces hepatic lipogenic enzyme gene expression while suppressing hepatosteatosis in obese female Zucker rats bearing DMBA-initiated mammary tumors

Dietary soy protein induces hepatic lipogenic enzyme gene expression while suppressing hepatosteatosis in obese female Zucker rats bearing DMBA-initiated mammary tumors

... Fatty liver disease shows a range of morphological features including fatty liver (liver steatosis) to fatty liver associated with ...fatty liver) or in the absence of alcohol ...

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Hepatic steatosis, detected by hepatorenal index in ultrasonography, as a predictor of insulin resistance in obese subjects

Hepatic steatosis, detected by hepatorenal index in ultrasonography, as a predictor of insulin resistance in obese subjects

... fatty liver disease (liver steatosis) being one of its features, particularly closely related to insulin ...hepatic steatosis by abdominal ultrasonography, using hepatorenal index, is a ...

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Omega-3 for nonalcoholic fatty liver disease in children

Omega-3 for nonalcoholic fatty liver disease in children

... fatty liver disease in children is prevalent in the Canadian population and can lead to liver fibrosis, cirrhosis, transplant, and reduced life ...in liver steatosis and triglyceride ...to ...

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Article Reduction of Fat to Muscle Mass Ratio Is Associated with Improvement of Liver Sti ness in Diabetic Patients with Non-Alcoholic Fatty Liver Disease

Article Reduction of Fat to Muscle Mass Ratio Is Associated with Improvement of Liver Sti ness in Diabetic Patients with Non-Alcoholic Fatty Liver Disease

... It is well known that body weight reduction leads to improvement of NAFLD [7]. In addition to that, the modification in body composition contributes to preventing life-threatening diseases [8]. Loss of body weight ...

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Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway

Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway

... SREBP1 is a critical regulator of lipid metabolism, in which it promotes expressions of lipogenic genes such as FASN and ACC, and it plays an important role in nonalcoholic fatty liver disease [32–34]. It has been ...

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