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liver stem/progenitor cells (LSPCs)

The Involving Roles of Intrahepatic and Extrahepatic Stem/Progenitor Cells (SPCs) to Liver Regeneration

The Involving Roles of Intrahepatic and Extrahepatic Stem/Progenitor Cells (SPCs) to Liver Regeneration

... the liver is severely damaged or hepatocyte proliferation is greatly inhibited, liver stem/progenitor cells (LSPCs) will contribute to the liver regeneration ...developing ...

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Downregulation of miR122 by grainyhead like 2 restricts the hepatocytic differentiation potential of adult liver progenitor cells

Downregulation of miR122 by grainyhead like 2 restricts the hepatocytic differentiation potential of adult liver progenitor cells

... The liver contains two types of epithelial cells, namely hepatocytes and cholangiocytes (biliary epithelial cells), which originate from fetal liver stem/progenitor cells ...

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Human liver mesenchymal stem/progenitor cells inhibit hepatic stellate cell activation: in vitro and in vivo evaluation

Human liver mesenchymal stem/progenitor cells inhibit hepatic stellate cell activation: in vitro and in vivo evaluation

... Mesenchymal stem cells (MSCs) have been proposed for the treatment of fibrosis based on their hepatocyte differentiation and regeneration potential as well as their immunomodulatory properties ...man ...

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Overview of stem cells and their research in burn patients

Overview of stem cells and their research in burn patients

... these cells have also demonstrated distinct ability to home to a variety of issues (muscles, heart, kidneys, skin, bone, liver, brain), where presumably, they variably contribute to tissue repair and ...

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Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis

Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis

... 3. Informed consents were obtained from the patients undergoing to the cell infusion procedure. The exclu- sion criteria were: 1. Patients with contraindications to hepatic artery cannulation; 2. Chronic hepatic ...

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Expansion of Non-Enriched Cord Blood Stem/Progenitor Cells CD34+ CD38- Using Liver Cells

Expansion of Non-Enriched Cord Blood Stem/Progenitor Cells CD34+ CD38- Using Liver Cells

... hematopoietic stem cells for allogeneic transplantation in children and adults with malignant and non-malignant diseases [1, ...nucleated cells (median 2 × 10 7 /kg) and CD34 + cells (median 2 ...

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Hyaluronan coating improves liver engraftment of transplanted human biliary tree stem/progenitor cells

Hyaluronan coating improves liver engraftment of transplanted human biliary tree stem/progenitor cells

... the liver paren- chyma, survive, proliferate, and enhance human albumin ...the liver, an enormous advantage for cell therapies targeting the liver ...of cells to remain confined to the ...

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Nutritional regulation of stem and progenitor cells in Drosophila

Nutritional regulation of stem and progenitor cells in Drosophila

... insulin-producing cells (IPCs) in the brain, which are homologous to pancreatic beta cells in ...the liver/adipose tissue in the fly, in response to fat, sugar and amino acid levels (Colombani et ...

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Alcohol Increases Liver Progenitor Populations and Induces Disease Phenotypes in Human IPSC-Derived Mature Stage Hepatic Cells

Alcohol Increases Liver Progenitor Populations and Induces Disease Phenotypes in Human IPSC-Derived Mature Stage Hepatic Cells

... adult liver functions. However, how alcohol affects human liver development and liver progenitor cells remains largely ...pluripotent stem cells (iPSCs) as a model to ...

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ALDH1A1-overexpressing cells are differentiated cells but not cancer stem or progenitor cells in human hepatocellular carcinoma

ALDH1A1-overexpressing cells are differentiated cells but not cancer stem or progenitor cells in human hepatocellular carcinoma

... overexpressing cells. We defined ALDH1A1- overexpressing cells as more intensely stained cells, compared with perivascular hepatocytes, which show moderately strong expression in the surrounding ...

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Hepatic stellate cells contribute to progenitor cells and liver regeneration

Hepatic stellate cells contribute to progenitor cells and liver regeneration

... validate stem cell characteristics of ...established liver progeni- tor cells, which are called oval cells in rodents, could represent an intermediate stage during hepatic differentiation of ...

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Vascular stem cells in diabetic complications: evidence for a role in the pathogenesis and the therapeutic promise

Vascular stem cells in diabetic complications: evidence for a role in the pathogenesis and the therapeutic promise

... in liver [76], spleen [76], and adipose tissue ...other progenitor cell types, MPCs share properties of both stem cells and mature ...Mesenchymal cells in culture typically exude a ...

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Is Adipocyte Differentiation the Default Lineage for Mesenchymal Stem/Progenitor Cells after Loss of Mechanical Loading? A Perspective from Space Flight and Model Systems

Is Adipocyte Differentiation the Default Lineage for Mesenchymal Stem/Progenitor Cells after Loss of Mechanical Loading? A Perspective from Space Flight and Model Systems

... other stem cells, crowding out the normal environment with fat could lead to im- paired blood cell ...the liver, heart, and potentially the ...

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“Too much guts and not enough brains”: (epi)genetic mechanisms and future therapies of Hirschsprung disease — a review

“Too much guts and not enough brains”: (epi)genetic mechanisms and future therapies of Hirschsprung disease — a review

... neuronal cells might not be sufficient to colonize the aganglionic ...when cells derived from human ganglionic bowel biopsies were cultured in the presence of GDNF ...

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Encapsulation of hepatic progenitor cells for liver tissue engineering

Encapsulation of hepatic progenitor cells for liver tissue engineering

... Tissue engineering is the science of using living cells to restore and rebuild tissues and organs. Engineered tissues could greatly reduce the need for organ replacement and could also help in the development of ...

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Vol 70, No 3 (2018)

Vol 70, No 3 (2018)

... hematopoietic stem cells; HSPC − hematopoietic stem/progenitor cells; HOXB4 – homeobox protein Hox-B4; TNC –total nucleated cells; CFU – colony forming unit; MSC – mesenchymal ...

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Neural stem and progenitor cells in cancer and development

Neural stem and progenitor cells in cancer and development

... contain stem or progenitor cells that might contribute some or all of the neural crest derivatives shown previously to arise from the late-emigrating population of neural crest cells (Korade ...

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Cancer stem cell metabolism

Cancer stem cell metabolism

... cancer cells, which generate their energy mainly via glycolysis ...confers stem-like traits and is associated with metastatic potential and resistance to DNA damage ...cancer cells also exhibit high ...

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The characterisation of endometrial epithelial stem/progenitor cells

The characterisation of endometrial epithelial stem/progenitor cells

... sorted cells, it seems that it was purely the low concentrations of hTERT mRNA rather than alternative splicing which made qPCR on these samples difficult and imprecise (Hapangama et al, 2008; Hapangama et al, ...

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Early-stage bilayer tissue-engineered skin substitute formed by adult skin progenitor cells produces an improved skin structure in vivo

Early-stage bilayer tissue-engineered skin substitute formed by adult skin progenitor cells produces an improved skin structure in vivo

... dermal cells; however, the number of normal hair follicles was significantly decreased with longer culture time ...trichogenic cells in TESSs that fail to reconstitute skin ...

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