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Long-term graft survival

iPSC-derived MSC therapy induces immune tolerance and supports long-term graft survival in mouse orthotopic tracheal transplants

iPSC-derived MSC therapy induces immune tolerance and supports long-term graft survival in mouse orthotopic tracheal transplants

... We investigated the possible therapeutic benefits of Cymerus iPSC-derived MSCs on immune tolerance, graft hypoxia, ischemia, tissue injury, and progression of fibrosis during airway transplantation. In order to ...

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How the definition of acceptable antigens and epitope analysis can facilitate transplantation of highly sensitized patients with excellent long-term graft survival

How the definition of acceptable antigens and epitope analysis can facilitate transplantation of highly sensitized patients with excellent long-term graft survival

... transplanted through the AM program compared to their highly sensitized counterparts transplanted through regular allocation. We demonstrated that long‐term graft survival was signific[r] ...

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Test of long-term uterine survival after allogeneic transplantation in rabbits

Test of long-term uterine survival after allogeneic transplantation in rabbits

... Although this case series of allo-UTn described only five cases, it highlighted a few challenges with the choice of animal model and the complexity of the surgical procedure involved. The macrovascular patch technique ...

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Age-associated decrease in de novo donor-specific antibodies in renal transplant recipients reflects changing humoral immunity

Age-associated decrease in de novo donor-specific antibodies in renal transplant recipients reflects changing humoral immunity

... age should be considered in order to optimize immuno- suppressive drug dosing [8]. In the field of organ trans- plantation, most studies comparing old with young transplant recipients have focused on T-cell responses [9] ...

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Steroid withdrawal after renal transplantation: a retrospective cohort study

Steroid withdrawal after renal transplantation: a retrospective cohort study

... duced long-term graft survival when not appropriately diagnosed and treated [12, ...and graft loss after steroid with- drawal compared with steroid maintenance, more re- cent ...

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Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients

Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients

... expression of MAp44 in heart musculature has therefore been supposed to prevent complement-induced heart damage [16]. However, it may not be the only mechanism according to the finding in the present study, since low ...

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Surgery for nonsmall cell lung cancer

Surgery for nonsmall cell lung cancer

... bypass. Survival was significantly higher when placement on bypass was planned preoperatively ...good long-term outcomes ...patients, graft interposition is necessary (PTFE). ...

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Long-term survival without graft-versus-host-disease following infusion of allogeneic myeloma-specific Vβ T cell families

Long-term survival without graft-versus-host-disease following infusion of allogeneic myeloma-specific Vβ T cell families

... At sacrifice, all ATCT treated groups who received ei- ther naïve or activated Vbeta T cells or naïve unselected spleenocytes, had significantly lower myeloma cell infil- tration in the spleen compared to the control ...

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... layed graft function within one week post-transplant has a major adverse impact upon both short and long-term allograft survival () and knowing that acute rejection in the early ...

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Long-term graft function of cryostored alginate encapsulated rat islets

Long-term graft function of cryostored alginate encapsulated rat islets

... enable survival and function of adult rat and human islets in immunocom- petent mice without immunosuppression for > 7 months ...short-term graft (4 weeks) function without the need of ...

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Protocol: optimisation of a grafting protocol for oilseed rape (Brassica napus) for studying long-distance signalling

Protocol: optimisation of a grafting protocol for oilseed rape (Brassica napus) for studying long-distance signalling

... confirm long-distance phloem mobility of potential signalling compounds identified in isolated phloem sap from this ...the graft union and ena- bled a high short-term (up to 100 %) and a reasonable ...

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Long term prognostic significance of thrombolysis in myocardial infarction risk score after revascularization in non-ST elevation acute coronary syndrome

Long term prognostic significance of thrombolysis in myocardial infarction risk score after revascularization in non-ST elevation acute coronary syndrome

... the long-term cardiac mortality and MACE (major adverse cardiac events) following percutaneous coronary intervention (PCI), for NSTEMI were significantly higher against STEMI and stable ...

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Perioperative and postoperative risk factors for corneal graft failure

Perioperative and postoperative risk factors for corneal graft failure

... There are several limitations to our study, which need to be taken into account. First of all, our study design was based on a retrospective review of medical records. There- fore, the quality of data was certainly in ...

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Recipient comorbidity and survival outcomes after kidney transplantation : a UK wide prospective cohort study

Recipient comorbidity and survival outcomes after kidney transplantation : a UK wide prospective cohort study

... of graft failure for the different classes of obesity, therefore the broader category of obesity (BMI ...on graft survival was found when modelling center as a random effect (difference in ...of ...

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Radiofrequency Ablation of hepatocellular carcinoma: a meta-analysis of overall survival and recurrence-free survival

Radiofrequency Ablation of hepatocellular carcinoma: a meta-analysis of overall survival and recurrence-free survival

... resection have a comparable impact on overall (OS) and recurrence-free survival (RFS). Given the different therapeutic options that occur in patients with HCC in the initial stage, it is absolutely essential to ...

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Long term survival in pseudo Meigs’ syndrome caused by ovarian metastases from colon cancer

Long term survival in pseudo Meigs’ syndrome caused by ovarian metastases from colon cancer

... Our experience suggests that pseudo-Meigs’ syndrome can occur in a patient with colorectal cancer after metas- tasis to the ovaries, causing massive ascites and pleural ef- fusion. Aggressive treatment, including R0 ...

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Long term survival for a cohort of adults with cerebral palsy

Long term survival for a cohort of adults with cerebral palsy

... The original survey was performed between 1951 and 1964 (inclusive). Allowing for a notification lag of up to 5 years, we assumed completeness up to the birth cohort year 1959. The survey identified both prevalent and ...

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Young patients with colorectal cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long term: Analysis of survival and prognostic markers

Young patients with colorectal cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long term: Analysis of survival and prognostic markers

... overall survival after a diagnosis was made of colorectal cancer and significant prognostic markers of survival identified by first univariate and then multifactorial ...free survival was analysed ...

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The Karolinska experience of autologous stem-cell transplantation for lymphoma: a population-based study of all 433 patients 1994–2016

The Karolinska experience of autologous stem-cell transplantation for lymphoma: a population-based study of all 433 patients 1994–2016

... yields correlate with quicker engraftment. Furthermore, normalisation of platelets and hemoglobin was strongly influenced by yield. What is more, the harvest predicted short- and long-term survival, ...

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Comparison of short-term and survival outcomes for transanal natural orifice specimen extraction with conventional mini-laparotomy after laparoscopic anterior resection for colorectal cancer

<p>Comparison of short-term and survival outcomes for transanal natural orifice specimen extraction with conventional mini-laparotomy after laparoscopic anterior resection for colorectal cancer</p>

... We have successfully performed total laparoscopic anterior resection with intracorporeal anastomosis and transanal speci- men extraction in 52 colorectal cancer patients. This method can achieve minimal invasiveness and ...

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