Loop of Henle
Ammonium Handling by Superficial and Juxtamedullary Nephrons in the Rat: EVIDENCE FOR AN AMMONIA SHUNT BETWEEN THE LOOP OF HENLE AND THE COLLECTING DUCT
... Ammonium handling by deep nephrons was profoundly affected by acid loading. Absolute delivery to the bend of the loop of Henle increased twofold while fractional delivery rose from 1,222±108% to 1,780±132% ...
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A Sall1 NuRD interaction regulates multipotent nephron progenitors and is required for loop of Henle formation
... for loop of Henle formation To gain insight into the molecular pathways that are coordinately regulated by Sall1 and NuRD, we performed transcriptional profiling of E17 wild-type and Δ SRM mutant kidneys by ...
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Tubuloglomerular Feedback NONLINEAR RELATION BETWEEN GLOMERULAR HYDROSTATIC PRESSURE AND LOOP OF HENLE PERFUSION RATE
... The present experiments were performed to quantify the effect of changes in distal tubular sodium delivery on glomerular flow dynamics both below and above the normal physiologic range. Glomerular capillary pressure as ...
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Bicarbonate transport along the loop of Henle II Effects of acid base, dietary, and neurohumoral determinants
... The loop of Henle contributes to renal acidification by reabsorbing about 15% of filtered ...on loop of Henle bicarbonate transport (JHCO3) of acid- base disturbances and of several factors ...
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Regulation by adrenal corticosteroids of sodium and potassium transport in loop of Henle and distal tubule of rat kidney
... Studies were conducted to examine the effects of adrenalectomy (ADX) and selective, physiological adrenal corticosteroid replacement on sodium and potassium transport by the superficial loop of Henle and ...
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Bicarbonate transport along the loop of Henle I Microperfusion studies of load and inhibitor sensitivity
... We microperfused the loop of Henle (LOH) to assess its contribution to urine acidification in vivo. Under control conditions (Na HCO3- = 13 mM, perfusion rate approximately 17 nl/min- 1) net bicarbonate ...
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Mechanism of exaggerated natriuresis in hypertensive man: impaired sodium transport in the loop of henle
... During hypotonic saline loading in water diuresis, changes in free water clearance per 100 ml of glomerular filtrate (C H 2 O /C In ) were less at any given increment in urine flow per 100 ml of glomerular filtrate (V/C ...
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Effects of Ethacrynic Acid (a New Saluretic Agent) on Renal Diluting and Concentrating Mechanisms: Evidence for Site of Action in the Loop of Henle
... Solute i.e., sodium chloride reabsorption in the loop is greater than water reabsorption, corresponding to approximately 14 to 21%o of filtered sodium.2 A drug that would completely inhi[r] ...
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Loop of Henle bicarbonate accumulation in vivo in the rat
... the loop. Thus, loop bicarconate accumulation was apparently sufficient to allow new bicarbonate to enter at a rate comparable to that delivered to the early distal site during free flow, recognizing of ...
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Evidence for a concentration gradient favoring outward movement of sodium from the thin loop of Henle
... osmolality, 938 +/- 37 mosmol/kg H23. Vasa recta plasma values (in corresponding units of measurement) were: sodium, 284 +/- 11; potassium, 34 +/- 2; osmolality, 935 +/- 34. Mean values of paired differences (loop ...
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Randall’s plaque of patients with nephrolithiasis begins in basement membranes of thin loops of Henle
... of Henle, one might ask why plaque is larger and more common in CaOx-stone formers than in normal subjects, as many have observed before ...the loop of Henle could increase total calcium reabsorption ...
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The distribution of sodium potassium activated adenosine triphosphatase in medulla and cortex of the kidney
... Amphiuma. The high concentration of Na-K-ATPase in the red medulla of the kidney is probably related to the presence here of the thick ascending limb of the loop of Henle, and this has important ...
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Micropuncture study of water, electrolytes, and urea movements along the loops of henle in psammomys
... The mechanism by which the osmotic pressure increases in tubular fluid along the descending limb of the loop of Henle was examined in Psammomys undergoing salt diuresis. In two series of experiments, ...
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Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development
... large degree of overlap (S5A Fig). This allowed us to use the cell types found by Lindstro¨m and colleagues to classify the cell clusters found here, using a k-nearest neighbors approach (see Methods). NPCa–c were also ...
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Deep nephron function after release of acute unilateral ureteral obstruction in the young rat
... (cortical:juxtamedullary nephrons = 27.6 +/- 4.5% vs. 53.3 +/- 5.2% in controls, P less than 0.005) which suggests that single nephron glomerular filtration rate is redistributed to deep nephrons after release of UUO. In ...
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Consequences of potassium recycling in the renal medulla Effects of ion transport by the medullary thick ascending limb of Henle's loop
... Accumulation of K in the outer medulla, by reducing NaCl absorption, would increase volume flow through the loop of Henle and increase Na and water delivery to the distal nephron. K recycling thus might ...
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Mechanism of Natriuresis after Closure of Chronic Arteriovenous Shunts
... A selective inhibition of tubular reabsorption As a result, proximal peritubular capillary protein con- of the loop of Henle of superficial nephrons as a result centrationi and oncotic p[r] ...
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Effect of carbonic anhydrase inhibition on superficial and deep nephron bicarbonate reabsorption in the rat
... acetazolamide occurred in the superficial and deep loop of Henle and between the distal tubule and base collecting duct. Because water reabsorption in these segments could serve to generate transepithelial ...
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Effect of Extracellular Volume Expansion upon Sodium Reabsorption in the Distal Nephron of Dogs
... Micropuncture and microperfusion studies of the loop of Henle and the distal tubule during ECF volume expansion have failed to show depression of sodium reabsorption; indeed micropunctur[r] ...
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Differences between Saline and Mannitol Diuresis in Hydropenic Man
... reflect a limitation on the tubular transport of sodium in the ascending limb of the loop of Henle 5, 6, since this latter process probably is the source of solute necessary for generati[r] ...
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