low density lipoprotein
Role of oxidized low density lipoprotein in atherogenesis
... Minimally modified low density lipoprotein induces monocyte chemotactic protein I in human endothe- lial cells and smooth muscle cells. Macrophages express monocyte chemotactic protein ([r] ...
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Identification of a lymphocyte surface receptor for low density lipoprotein inhibitor, an immunoregulatory species of normal human serum low density lipoprotein
... for low density lipoprotein inhibitor (LDL-In), a subset of normal human serum low density lipoprotein (LDL) that has been previously demonstrated to suppress selected lymphocyte ...
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Influence of Flavonols As in vitro on Low Density Lipoprotein Glycation
... of Low density lipoprotein (LDL) is a naturally occurring chemical modification of apolipoprotein B as a result of condensation between lysine residues and ...
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Probucol inhibits oxidative modification of low density lipoprotein
... that low density lipoprotein (LDL) incubated with endothelial cells (EC) undergoes extensive oxidative modification in structure and that the modified LDL is specifically recognized by the acetyl LDL ...
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Cholesterol feeding increases low density lipoprotein synthesis
... of low density lipoproteins in a group of seven healthy ...high density and low density lipoprotein cholesterol levels by 18 and 40%, ...the low density ...
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Profile of Surrounding MicroRNAs in Low Density Lipoprotein Uptake
... * Correspondence: [email protected]; Tel.: +55-91-983400652 Abstract: The atherosclerosis, a chronic and inflammatory disease that occurs when there are high levels of low-density lipoprotein (LDL) ...
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Oxidized low density lipoprotein, stem cells, and atherosclerosis
... LDL to apoB receptors to decrease as the affinity to the scavenger receptors, such as CD36 and lectin like oxi- dized low density lipoprotein receptor-1 (LOX-1), increased [36]. (CD36 belongs to the ...
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Non high density lipoprotein cholesterol versus low density lipoprotein cholesterol as a discriminating factor for myocardial infarction
... Anti-oxidative property of HDL-C could be the other cardio-protective mechanism [15]. The differences in the median values of each lipid par- ameter were statistically significant between MI cases and controls which show ...
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N-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors
... Subsequently, low-density lipoprotein (LDL)-mediated NSC-NPs with loaded Ost (Ost/LDL-NSC-NPs) were obtained by coupling LDL with Ost/NSC-NPs through amide ...
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The association of very-low-density lipoprotein with ankle-brachial index in peritoneal dialysis patients with controlled serum low-density lipoprotein cholesterol level
... Japan). Lipoprotein fractions were analyzed by HPGPC as previously described ...each lipoprotein fraction to total cholesterol level (cholesterol proportion) were calculated mathematically with modified ...
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The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia
... of low density lipoprotein (LDL, beta lipoprotein) was studied in 10 normal individuals and 10 patients with familial type II hyperlipoproteinemia using purified radioiodinated ...
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Biologically active low density lipoprotein in human peripheral lymph
... We have compared the ability of human serum and peripheral lymph to suppress the activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), to activate cholesteryl ester synthesis, and to compete ...
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Role of Microtubules in Low Density Lipoprotein Processing by Cultured Cells
... J Clin Invest. 1979;63(1):75-84. https://doi.org/10.1172/JCI109281. The effect of the microtubule inhibitor colchicine on the metabolism of 125 I-low density lipoprotein (LDL) by cultured human skin ...
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Catabolism of Very Low Density Lipoprotein B Apoprotein in Man
... The turnover and the catabolic fate of the B apoprotein of very low density lipoprotein (VLDL-B) was studied in 15 normal and hyperlipidemic subjects using reinjected autologous VLDL labeled with ...
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Human macrophages limit oxidation products in low density lipoprotein
... Oxidative modification of low density lipoprotein (LDL) plays a major role in the pathogenesis of atherosclerosis. The first stage of atherogenesis is characterized by an influx and accumulation of ...
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Lipid composition of circulating multiple-modified low density lipoprotein
... modified low- density lipoprotein (LDL) induces pronounced accumulation of cholesterol and lipids in the arterial wall, while native LDL seems to lack such ...and density, desialylation, ...
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The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia
... of low density lipoprotein (LDL, beta lipoprotein) was studied in 10 normal individuals and 10 patients with familial type II hyperlipoproteinemia using purified radioiodinated ...
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Comparison of glucosylated low density lipoprotein with methylated or cyclohexanedione treated low density lipoprotein in the measurement of receptor independent low density lipoprotein catabolism
... We previously showed that glucosylation of lysine residues of low density lipoproteins (LDL) blocks high-affinity degradation by cultured human fibroblasts, and markedly slows LDL turnov[r] ...
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REDUCTION OF LOW-DENSITY LIpoprotein
... of all patients were unable to tolerate even low doses of any statin. The comparator in this trial, ezeti- mibe, considered the best alternative for LDL-C reduction and tolerability in stat- in-intolerant ...
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Receptor mediated Catabolism of Low Density Lipoprotein in Man QUANTITATION USING GLUCOSYLATED LOW DENSITY LIPOPROTEIN
... The latter is similar to the FCR reported for native LDL in subjects with homozygous familial hypercholesterolemia, supporting the interpretation that GLC-LDL traces only the receptor-in[r] ...
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