low-dose streptozotocin
Antinociceptive Property of TRIGONELLA FOENUM GRAECUM (FENUGREEK SEEDS) in High Fat Diet-Fed/Low Dose Streptozotocin Induced Diabetic Neuropathy
... Diabetic neuropathic pain is an important microvascular complication in diabetes mellitus and oxidative stress plays a vital role in associated neural and vascular complications. The present study investigated the effect ...
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Diabetic Blood Glucose Level Profile with Stratified Dose Streptozotocin (SD-STZ) and Multi Low Dose Streptozotocin (MLD-STZ) Induction Methods
... stratified dose streptozotocin (STZ-SD) and multi-low dose streptozotocin (MLD-STZ) induction ...stratified dose of 40, 35, 30, 25, and 20 mg/Kg of body weight for five ...a ...
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Antidiabetic Effect of Sargassum wightii and Ulva fasciata in High fat diet and Multi Low Dose Streptozotocin Induced Type 2 Diabetic Mice
... This study was undertaken to evaluate the antidiabetic effect of edible seaweeds Sargassum wightii and Ulva fasciata with an objective to establish these seaweeds as add-on therapy for controlling diabetes. The ethyl ...
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Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin
... of low dose streptozotocin (STZ) after fourteen days at 15, 20, 25 or 30 mg/kg body ...a dose-dependent increase in blood glucose and plasma lipids with increasing concentrations of ...a ...
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SYNTHESIS AND EVALUATION OF ANTIDIABETIC PROPERTIES OF A ZINC MIXED LIGAND COMPLEX IN HIGH FAT DIET LOW DOSE STREPTOZOTOCIN INDUCED DIABETIC RATS
... tissues. The levels of these markers were significantly reduced in zinc mixed ligand complex treated diabetic rats, indicating the beneficial effect of the complex in ameliorating diabetes-associated renal complications. ...
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ANTIDIABETIC POTENTIAL OF PERILLYL ALCOHOL, A MONOTERPENE ON HIGH FAT DIET LOW DOSE STREPTOZOTOCIN INDUCED DIABETES IN EXPERIMENTAL RATS
... Magdalena et al. [16]. The composition (Table 1) and preparation of HFD are shown below (58% fat, 25% protein, and 17% carbohydrate, as a percentage of total kcal has been described earlier [17]. After 4 weeks of dietary ...
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Nephroprotective Effect of Naringenin Against Multiple Low Dose Streptozotocin (MLDSTZ) Induced Renal Damage in Mice
... significant dose dependent reduction upon treatment with naringenin (Table 1) Oral administration of naringenin retards the formation of TBARS and hydroperoxides in STZ- treated kidney ...
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on islet α cell and β cell in multiple low dose streptozotocin-induced diabetes rats
... by streptozotocin. Streptozotocin-induced diabetes rats were orally administrated with 1,25-di- hydroxyvitamin D 3 every day for 4 ...by streptozotocin probably through downregulating the expression ...
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HEPATOPROTECTIVE EFFECT OF PERILLYL ALCOHOL (POH) ON HIGH FAT DIET LOW DOSE STREPTOZOTOCIN INDUCED TYPE 2 DIABETES IN EXPERIMENTAL RATS
... injected intraperitoneally with a low dose of STZ (35 mg/kg b.w.) dissolved in 0.1M cold citrate buffer, pH 4.5). 3 days after STZ injection, the rats were screened for blood glucose level. Rats having ...
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Metformin 3 hydroxyflavone, A New Schiff Base Complex Modulates the Activities of Carbohydrate Regulatory Enzymes in High Fat Diet Fed Low Dose Streptozotocin Induced Type 2 Diabetes in Experimental Rats
... High fat diet fed-low dose STZ induced rats showed increased levels of fasting blood glucose levels and glycosylated hemoglobin. The observed decrease in the level of hemoglobin in insulin resistant ...
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Inosine Protects Against the Development of Diabetes in Multiple-Low-Dose Streptozotocin and Nonobese Diabetic Mouse Models of Type 1 Diabetes
... islet transplantation. Graft rejection was diagnosed by return of hyperglycemia accompanied by glucosuria and ketonuria. Inosine reduced the incidence of diabetes in both streptozotocin-induced diabetes and ...
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Biochemical and histological parameters in induced type 2 diabetic rats fed with high fat diet without exogenous cholesterol and low dose streptozotocin
... relative low serum level of albumin in the HFD + STZ (35 mg/kg bw) experimental group (Table 3) could also be explained because of the lower biosynthesis of the protein in the liver related to the deleterious ...
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A comparison of metabolomic changes in type-1 diabetic C57BL/6N mice originating from different sources
... mechanisms, streptozotocin is widely used to induce experimental type-1 diabetic animal models ...with low dose streptozotocin results in the slowly progressive type-1 diabetes and more ...
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Quercetin Attenuates Altered Colonic Contractility and Intestinal Transit In Hfd-Fed / Stz-Treated Type 2 Diabetic Rats.
... single dose of STZ induced a diabetic state similar to prediabetic, insulin resistant state in humans ...(17). Streptozotocin targets pancreatic β cells, leading to serum insulin ...a low dose ...
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An experimental study to evaluate the hypoglycemic and anti inflammatory effect of ficus religiosa and its comparison with glibenclamide
... relievers (Arora et al., 1999; Govindrajan et al., 2005). However, the plant has not been widely studied for its hypoglycemic/ anti- hyperglycemic effects, except for a few preliminary studies (Kirana et al., 2009; ...
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Development of an Experimental Model of Metabolic Syndrome in Sprague Dawley Rat
... alloxan, streptozotocin, glucocorticoid agent (Bertram & Hanson, ...of low dose streptozotocin and high fat diet derived from hydrogenated ...
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ANTI DIABETIC ACTIVITY OF SALACIA CHINENSIS STEM EXTRACT
... Glibenclamide at the dose of 5 mg/kg showed significant (P<0.01) increase in blood glucose level on Day 07 of the drug treatment, whereas S.chinensis at the dose levels of 200 and 400 mg/kg body weight ...
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EFFECT OF ETHANOLIC EXTRACT OF LEAVES OF PASSIFLORA INSARNATA LINN IN STREPTOZOTOCIN INDUCED DIABETES IN RATS
... The temperature in the experimental animal room should be 22ºC (+3ºC). Although the relative humidity should be at least 30% and preferably not exceed 70% other than during room cleaning the aim should be 50-60%. ...
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OLIVE AND ITS ANTIOXIDANT MOLECULE OLEUROPEIN FOR MANAGEMENT OF OBESITY AND DIABETES: A REVIEW
... study by Drira et al. [49] on 3T3-L1 adipocytes, it was found that Oleuropein inhibits differentiation. Inhibition of transcription factors PPAR-γ, C/EBPα, SREBP-1c occurred after the addition of Oleuropein. SREBP-1c ...
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The Effect of Low‑Dose Ketamine (Preemptive Dose) on Postcesarean
... drug, dose, and method of Ketamine prescription and in the end general ...concluded; low dose ketamine in both two groups (P = ...higher dose ketamine in cesarean under spinal anesthesia] and ...
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