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lumbar spinal cord

Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord

Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord

... the lumbar spinal cord in the pioglitazone-treated rats have been measured and compared with equivalent measurements in the morphine-injected ...the lumbar spinal ...rat spinal ...

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Transcriptomic evidence of a para-inflammatory state in the middle aged lumbar spinal cord

Transcriptomic evidence of a para-inflammatory state in the middle aged lumbar spinal cord

... increased in the brains of aging rodents [27] and non- human primates [45]. MHCII complex, identified in the canonical pathways up modulated in LSC, is key on APC/T-cell interface [24]. Consistent with M1 state acti- ...

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A new pharmacological role for donepezil: attenuation of morphine-induced tolerance and apoptosis in rat central nervous system

A new pharmacological role for donepezil: attenuation of morphine-induced tolerance and apoptosis in rat central nervous system

... After fixation and OCT embedding, the samples were cut into 3 μm-thick with a Cryocut apparatus (Leica 1800, Germany). For the TUNEL assay, an in situ Cell Death Detection kit (Roche Applied Science, Cat # 11 684 817 ...

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Inhibition of chemokine CX3CL1 in spinal cord mediates the electroacupuncture-induced suppression of inflammatory pain

<p>Inhibition of chemokine CX3CL1 in spinal cord mediates the electroacupuncture-induced suppression of inflammatory pain</p>

... (P<0.01). Spinal cord tissues were then collected at day 3 after modeling when the last behavioral tests were ...in lumbar spinal cord was not affected by CFA modeling, EA treatment ...

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Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

... We identified TLR4 up-regulation in the lumbar spinal cord of hSOD1 G93A mice, where it was localised pre- dominantly to astrocytes and some microglia. Import- antly, HMGB1, an endogenous cell ...

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MicroRNA-142 regulates inflammation and T cell differentiation in an animal model of multiple sclerosis

MicroRNA-142 regulates inflammation and T cell differentiation in an animal model of multiple sclerosis

... that lumbar spinal cord is the location which shows higher levels of inflammation and demyelination more consistently [26, ...on lumbar spinal cord tissue for further expression ...

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Prion Strain Targeting Independent of Strain-Specific Neuronal Tropism

Prion Strain Targeting Independent of Strain-Specific Neuronal Tropism

... the lumbar spinal cord results in retrograde transport of both the DY and HY TME agents via the corticospinal, rubrospinal, vestibulospinal, and reticulospinal descending motor ...

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Axonal degeneration in paraplegin deficient mice is associated with abnormal mitochondria and impairment of axonal transport

Axonal degeneration in paraplegin deficient mice is associated with abnormal mitochondria and impairment of axonal transport

... bar spinal cord are characteristically confined to the anterolateral funiculi and never detected in the dorsal columns, indicating that they (a) are not due to arti- facts, (b) correlate with the ...

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Combined intramuscular and intraspinal transplant of bone marrow cells improves neuromuscular function in the SOD1G93A mice

Combined intramuscular and intraspinal transplant of bone marrow cells improves neuromuscular function in the SOD1G93A mice

... the lumbar spinal cord, we found a tendency to have higher number of surviving neurons in BMC-injected ...serve lumbar ventral horn MNs [21], For these reasons, we decided to inject BMCs in ...

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Retrograde Transport of Transmissible Mink Encephalopathy within Descending Motor Tracts

Retrograde Transport of Transmissible Mink Encephalopathy within Descending Motor Tracts

... the lumbar spinal cord, subsequent transneuronal spread to spinal tracts that terminate in the lumbar spinal cord, and then retrograde axonal transport to nuclei in the ...

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Sustained Expression of TDP-43 and FUS in Motor Neurons in Rodent's Lifetime

Sustained Expression of TDP-43 and FUS in Motor Neurons in Rodent's Lifetime

... Animal tissues were fixed 4% paraformalde- hyde, cryopreserved in 30% sucrose, and cut into three series of consecutive sections (20 μm) at a Cryostat. Each set of tissue sections was immunos- tained for TDP-43, FUS, or ...

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Surgical Management of an Unstable Lumbar Fracture Dislocation—A Case Report

Surgical Management of an Unstable Lumbar Fracture Dislocation—A Case Report

... sustain spinal column injuries in the United States [1]. The lumbar spine is the most common sites for fractures because of the high mobility of the lumbar spine ...the lumbar spine can occur ...

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A finite element modeling of the human lumbar unit including the spinal cord

A finite element modeling of the human lumbar unit including the spinal cord

... ing combination. The identification of the parameters, leading to neurological deficit during walking (Neutro- genic claudication) can help to understand and prevent all these phenomena. Based on clinical observations, ...

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WWL70 protects against chronic constriction injury-induced neuropathic pain in mice by cannabinoid receptor-independent mechanisms

WWL70 protects against chronic constriction injury-induced neuropathic pain in mice by cannabinoid receptor-independent mechanisms

... On day 7 after CCI surgery, mice were euthanized, and the sciatic nerves, DRG, and spinal cords were dissected out. Total RNA was extracted from tissues using Trizol reagent (Sigma, St Louis, MO). Gene expression ...

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Regeneration of supraspinal projections after spinal cord injury in the neonatal opossum, Monodelphis domestica

Regeneration of supraspinal projections after spinal cord injury in the neonatal opossum, Monodelphis domestica

... 4.1 NEONATAL MONODELPHIS AS A MODEL FOR REGENERATION 87 4.2: THE DEVELOPMENT OF DESCENDING SUPRASPINAL PROJECTIONS TO THE LUMBAR REGION OF THE SPINAL CORD IN MONODELPHIS 90 4.3: RECONSTR[r] ...

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The practical use of computed tomography in evaluation of shell lesions in six loggerhead turtles Caretta caretta

The practical use of computed tomography in evaluation of shell lesions in six loggerhead turtles Caretta caretta

... ABSTRACT: Six adult loggerhead turtles were found stranded and were rescued near Sicily within a period of 12 months. Macroscopically apparent lesions of the shell were present. After thorough physical examination, ...

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Complete myelography with metrizamide

Complete myelography with metrizamide

... Thorough myelography of the entire spinal cord including the foramen magnum region can be accomplished consistently and promptly after metrizamide injection via lumbar or lateral cervica[r] ...

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Rehabilitation Outcome in Traumatic Spinal Cord Injury at Thoracic and Lumbar Region.

Rehabilitation Outcome in Traumatic Spinal Cord Injury at Thoracic and Lumbar Region.

... complete cord injury compared to 28% of incomplete cord injury ...the spinal cord lesion as revealed by the table 6, which is consistent with previous studies Drewes AM et al study from ...

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Counteracting roles of MHCI and CD8+ T cells in the peripheral and central nervous system of ALS SOD1G93A mice

Counteracting roles of MHCI and CD8+ T cells in the peripheral and central nervous system of ALS SOD1G93A mice

... the spinal cord of 13-day-old (E13) NTG+/+ or NTG−/− mouse embryos, as previously described ...from spinal cords, exposed to DNAse and trypsin (Sigma-Aldrich) and centrifuged with a bovine serum ...

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Neurohistopathological Findings of the Effects of Amprolium on the Brain and Spinal Cord Changes in the a Animal Model: An Experimental Study

Neurohistopathological Findings of the Effects of Amprolium on the Brain and Spinal Cord Changes in the a Animal Model: An Experimental Study

... the spinal cord and four cross sections from cervical, thoracic, lumbar and sacral levels were observed only in seven animals and characterised by mild to moderate perineuronal oedema, congestion, ...

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