lung epithelial cells
mAChRs activation induces epithelial-mesenchymal transition on lung epithelial cells
... Accumulating evidence has indicated that, in addition to Smad2-mediated pathways [3,10,36], other pathways, such as the p38, ERK, c-Jun N-terminal kinase, and mitogen-activated protein kinase pathways have been im- ...
11
Mutant AKT1-E17K is oncogenic in lung epithelial cells
... transforms lung epithelial cells using human normal bronchial epithelial cells immortalized by infection with Adenovirus 12/SV40 hybrid virus (BEAS-2B) ...of lung cancer [35–37]. ...
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Streptococcus pneumoniaeearly response genes to human lung epithelial cells
... host epithelial cells have been characterized in ...pharyngeal epithelial cells (Detroit 562) for 3 ...human lung epithelial cells (A549) for 1 h and 3 h, respectively ...
10
Pneumocystis carinii inhibits cyclin dependent kinase activity in lung epithelial cells
... mink lung epithelial ...the epithelial lining in the alveolar space (11, ...net epithelial cell loss is a direct consequence of inhibitory ef- fects of ...the lung epi- ...A549 ...
9
The interaction of Francisella tularensis with lung epithelial cells
... We were unable to identify the characteristic membrane ruffling that is seen with Salmonella invasion either by phalloidin staining or Field Emission Scanning Electron Microscopy (FESEM) under conditions where we were ...
170
Epithelial stem cells of the lung: privileged few or opportunities for many?
... adult lung epithelial cells together with embryonic lung mesenchyme and then graft the recombinants under the kidney capsule of immunocompromised ...stem cells and regeneration in the ...
11
Induction of Alternatively Activated Macrophages Enhances Pathogenesis during Severe Acute Respiratory Syndrome Coronavirus Infection
... acute lung injury (ALI) that often leads to se- vere lung ...severe lung pathology with pre-pulmonary-fibrosis-like lesions, and an altered immune response following infection with ...severe ...
16
PubMedCentral-PMC4867233.pdf
... in lung epithelial cells and fibroblasts primarily used exogenous pre-miRNA transfected into ...primary cells with an important role in lung biology and relevant derivative cell ...
27
Original Article NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of Acute Respiratory Distress Syndrome
... of epithelial cells was observed in biopsies and bronchoalveolar lavage fluid from patients with ARDS [3], and the severity of lung injury has been correlated with the degree of alveolar ...
15
The cellular kinetics of lung alveolar epithelial cells and its relationship with lung tissue repair after acute lung injury
... Male Sprague-Dawley rats, 220–250 g, were anaesthetized with pentobarbital sodium (60 mg/kg). Immediately after induction of anaesthesia. We inserted a catheter into the femoral artery and registered the blood pressure. ...
10
CCR10+ epithelial cells from idiopathic pulmonary fibrosis lungs drive remodeling
... IPF lung epithelial cells were generated by culturing normal or IPF explant suspensions using CRC as previously described (19, 20, 62) with few modifications or in PneumaCult-Ex Plus Medium (STEMCELL ...
22
Intersections of lung progenitor cells, lung disease and lung cancer
... between epithelial progenitors, endothelial cells and mesenchymal cells in the ...distal lung epithelial cells require stromal cell inputs ( perhaps secretory and structural in ...
6
CD10/neutral endopeptidase 24 11 regulates fetal lung growth and maturation in utero by potentiating endogenous bombesin like peptides
... Abstract Bombesin-like peptides BLPs are mitogens for bronchial epithelial cells and small cell lung carcinomas, and increase fetal lung growth and maturation in utero and in organ cultu[r] ...
6
The therapeutic effects of bone marrow-derived mesenchymal stromal cells in the acute lung injury induced by sulfur mustard
... SM-induced lung injury model, these pathological changes, together with the elevated expression of total protein and W/D weight ratio, were ...inflammatory cells infil- tration into alveoli were ...W/D ...
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Maintenance of human amnion epithelial cell phenotype in pulmonary surfactant
... experimental lung injury ...stem cells to replace damaged tissue ...stem cells (MSCs) were able to reduce lung injury, in part, through activation and recruitment of endogenous bronchoalveolar ...
7
Prognostic value of immunohistochemical surfactant protein A expression in regenerative/hyperplastic alveolar epithelial cells in idiopathic interstitial pneumonias
... cal lung biopsy between 1995 and 2006 and were fol- lowed for at least three years after biopsy in the National Hospital Organization group hospitals in Kyushu District (Omuta, Fukuoka Higashi, Minami Kyushu, and ...
9
Lung ageing and COPD: is there a role for ageing in abnormal tissue repair?
... ageing lung into three categories: changes in lung structure, changes in the chest wall and changes in respiratory muscles ...the lung are mainly attributed to an increase in the size of the alveolar ...
15
Isolation of human β-defensin-4 in lung tissue and its increase in lower respiratory tract infection
... uginosa rather than against E. coli, along with its stronger antimicrobial activity relative to that of hBD-2, under- scores the deep involvement of hBD-4 in the innate immunity of the lower respiratory tract. The ...
9
<p>Analyzing biological and molecular characteristics and genomic damage induced by exposure to asbestos</p>
... in lung cancer, observed more frequently in tumors of patients exposed to asbestos than in unexposed ...in lung tissue and partial or total losses of chromosomes 1, 4, and 9, and chromosomal rear- ...
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Transcriptomic analysis comparing mouse strains with extreme total lung capacities identifies novel candidate genes for pulmonary function
... 10. Soler Artigas M, Wain LV, Repapi E, Obeidat M, Sayers I, Burton PR, Johnson T, Zhao JH, Albrecht E, Dominiczak AF, Kerr SM, Smith BH, Cadby G, Hui J, Palmer LJ, Hingorani AD, Wannamethee SG, Whincup PH, Ebrahim S, ...
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