Lung Tissues
Immunohistochemical Localization of Aspergillus and p53 in Human Lung Tissues
... Aspergilli are filamentous fungi which can cause opportunistic infections in Acquired Immunode- ficiency Syndrome (AIDS) patients. Aspergilli can be found in human tissues either in the form of spores or hyphae. ...
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Nramp1 gene expression in different tissues of Meishan piglets from newborn to weaning.
... and lung tissues, which affects not only autoimmunity, but also resistance to Salmonella and various other in- tracellular pathogenic microorganisms (Blackwell, 1996; Lam-Yuk-Tseung et ...
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m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis
... human lung cancer tissues and cancer cells than in normal adjacent lung tissues and control cells, respectively ...human lung tumor tissues (T) com- pared to their normal ...
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Down-regulation of USP13 mediates phenotype transformation of fibroblasts in idiopathic pulmonary fibrosis
... IPF lung tissues. a Gene expression profiles of fibrotic lung tissue from IPF patients ( n = 5) and of normal lung tissues from primary spontaneous pneumothorax patients ( n = ...IPF ...
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Overexpression of Grb2-associated Binder 2 in Human Lung Cancer
... normal lung tissues, 40 squamous cell carcinomas, 37 adenocarcinomas and 20 other types of lung cancers) were sectioned (4 μm thick), mounted on poly- L -lysine-coated glass slides, and allowed to ...
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Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway
... Recent researches have revealed the functional roles of lncRNAs [54–56], and provided insights into the molecular mechanisms by which lncRNAs function in a variety of human tumors [57–65]. Nevertheless, the mechanisms of ...
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Lysyl hydroxylase 2 induces a collagen cross link switch in tumor stroma
... human lung cancer, we probed a database that compares human lung can- cer with normal lung tissues ...normal lung) in at least one of the human datasets (Figure ...
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IL-24 modulates the high mobility group (HMG) A1/miR222 / AKT signaling in lung cancer cells
... normal lung and lung tumor tissues, we performed immunohistochemistry (IHC) in a commercially available tissue microarray (TMA; BC041115b; US Biomax, ...of lung cancer tissues and ...
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Original Article MEG3 regulates the invasion and migration of lung cancer via targeting miR-219a and through MAPK pathway
... in lung cancer tissue was significantly down- regulated compared with normal lung ...in lung cancer cell lines was performed in order to verify the role of MEG3 expression in the development of ...
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Original Article The downregulation of Bcl-xL/Bcl-2-associated death promoter indicates worse outcomes in patients with small cell lung carcinoma
... cell lung cancer tissues compared to normal lung tissues and demonstrated that the loss of Bad may be an independent and power- ful predictor of adverse prognosis in NSCLC ...
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Minichromosome maintenance protein 2 correlates with the malignant status and regulates proliferation and cell cycle in lung squamous cell carcinoma
... LUSC tissues compared with paired adjacent normal lung tissues or lung adenocarcinoma tissues through analyzing microarray data sets (GSE3268 and GSE10245), which confirmed that MCM2 ...
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Suppressed nuclear factor-kappa B alleviates lipopolysaccharide-induced acute lung injury through downregulation of CXCR4 mediated by microRNA-194
... inflammatory level while down-regulating the expres- sion of miR-194 or adding the NF-κB inhibitor. Then, the lung tissues were collected for HE staining (Fig. 5a). The results showed that compared with the ...
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An expression meta-analysis of predicted microRNA targets identifies a diagnostic signature for lung cancer
... normal lung tissues, the 17-gene signature has no differ- ence in expression in the airway epithelial cells taken from smokers diagnosed with AD or SCC, and most genes had reduced expression in the ...
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PRDM16 functions as a suppressor of lung adenocarcinoma metastasis
... in lung cancer patients, we first analyzed the gene expression datasets of human lung adenocarcinomas and lung squamous cell carcin- ...in lung adenocarcinoma and lung squamous cell ...
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Attenuation of Porcine Reproductive and Respiratory Syndrome Virus by Molecular Breeding of Virus Envelope Genes from Genetically Divergent Strains
... chimera in vivo, since only low levels of chimera DS5M3 viral RNA were detected in both sera and lung tissues in the pathogenicity study. The GP5-M DNA shuffling included some critical regions for virus ...
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Original Article Relationship between expression of MAS-related GPR family member D and clinicopathological characteristics in pancreatic cancer
... normal tissues. As for lung cancers, the mean level of MRGPRD mRNA in the lung cancer tis- sues exceeded the amount equal to three times as much as that in the normal lung tissues, and ...
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Pathologically decreased expression of miR-193a contributes to metastasis by targeting WT1-E-cadherin axis in non-small cell lung cancers
... 4 lung cancer cells were put into the upper ...5 lung cancer cells were put into the upper compartment per well with the Matrigel-coated membrane (BD Biosciences, San Jose, USA), which was diluted with ...
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LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway
... To explore the mechanism underlying the involvement of LPCAT1 in tumor metastasis, we set out to identify the relevant signaling pathways accounting for tumor growth inhibition caused by LPCAT1 knockdown. MYC plays an ...
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The methylation profiles of PRDM promoters in non–small cell lung cancer
... the tissues using Universal Genomic DNA Extraction Kit (Takara, Tokyo, Japan), and modified by bisulfite treatment with EZ-DNA methylation kit (Zymo Research, Orange, CA, USA) according to the manufacturer’s ...
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Original Article Increased expression of the lncRNA PVT1 promotes tumorigenesis in non-small cell lung cancer
... Total RNA was isolated from tissues or cells using TRIZOL reagent according to the manu- facturer’s protocol (Invitrogen). RNA was rever- se transcribed using SuperScript First Strand cDNA System (Invitrogen) ...
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