lymphoblastoid cell
Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines
... immortal lymphoblastoid cell lines (LCLs), providing a model for EBV-mediated ...mediate cell-cell adhe- ...a cell adhesion molecule on primary B cells that may play a role in the tu- ...
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Transcript Isoform Variation Associated with Cytosine Modification in Human Lymphoblastoid Cell Lines
... ABSTRACT Cytosine modification on DNA is variable among individuals, which could correlate with gene expression variation. The effect of cytosine modification on interindividual transcript isoform variation (TIV), however, ...
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A Study of Using Lymphoblastoid Cell Lines in Pharmacogenomics and Drug Family Clustering.
... Background: The large sample sizes, freedom of ethical restrictions and ease of repeated mea- surements make cytotoxicity assays of immortalized lymphoblastoid cell lines (LCLs) a powerful new in vitro ...
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Lymphoblastoid cell lines: a continuous in vitro source of cells to study carcinogen sensitivity and DNA repair
... Apart from this, LCLs have also expanded their niche as a tool for a variety of DNA damage/repair studies. An excellent utilization of LCLs for such kind of research was done by Motykiewicz et al., where DNA repair ...
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Molecular insight into thiopurine resistance: transcriptomic signature in lymphoblastoid cell lines
... Transcriptomic analysis is a powerful tool for charac- terizing susceptibility and resistance to drugs [17,18]. This approach can uncover previously unrecognized mechanisms of drug response and provides information on ...
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Impairment of natural killer functions by interleukin 6 increases lymphoblastoid cell tumorigenicity in athymic mice
... The lymphoblastoid cells expressing IL-6 were indistinguishable from parental cell lines in morphology and in a variety of cell surface characteristics, and did not exhibit growth advantage over ...
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Receptors for complement and immunoglobulin on human leukemic cells and human lymphoblastoid cell lines
... human lymphoblastoid cell lines were examined for the presence of the EAC¢ and EA ...the cell lines studied could be classified as B lymphocytes by the presence of the EAC¢ receptor and absence of ...
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Genetic and genomic stability across lymphoblastoid cell line expansions
... Objective: Lymphoblastoid cell lines are widely used in genetic and genomic ...across cell line expansions, which are commonly used in biorepository ...and cell lines sampled from six research ...
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Limitations of lymphoblastoid cell lines for functional analysis of SNPs
... chose lymphoblastoid cell lines harboring AA/ GA/GG genotype and acquired two for each genotype from National Human Genome Research Institute ...the cell lines with the previous findings in ...
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Metabolic activation of 9([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human lymphoblastoid cell lines infected with Epstein-Barr virus.
... The results indicate that BW B759U, in contrast to ACV, is preferentially phosphorylated in human lymphoblastoid cell lines infected with EBV and that the triphosphate of BW B759U persis[r] ...
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Infection of Lymphoblastoid Cell Lines by Kaposi's Sarcoma-Associated Herpesvirus: Critical Role of Cell-Associated Virus
... lymphoid cell lines for infectibility by ...B cell lines), BCBL1 and JSC1 (KSHV-positive PEL lines), and Jurkat and SupT1 (T cell ...of cell fusion events occurred, and lymphoid and ...
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Induction of selective cytotoxicity and apoptosis in human T4 lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest
... CEMss cells were seeded in 12-well plates and treated with boesenbergin A (8 μ g/ml) at 3, 6, 12 and 24 h. The total protein of the cells was extracted with cell lysis buffer (50 mM Tris – HCl pH 8.0, 120 mM NaCl, ...
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The mode of lymphoblastoid cell death in response to gas phase cigarette smoke is dose-dependent
... ensuing cell damage, which more than likely happens when either CSC or CSE is used to chal- lenge cultured ...first cell lineage directly exposed to the toxic effects of tobacco smoke ...
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Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen dependent T cell leukemia 1A (TCL1A) gene mediated regulation of cytokine expression
... in lymphoblastoid cell lines (LCLs) that carried variant sequences for the chromosome-14 SNPs; that is, in cell lines with DNA encoding the SNP-related ...
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Interchromosomal Gene Conversion at an Endogenous Human Cell Locus
... To examine the relationship between gene conversion and reciprocal exchange at an endogenous chromosomal locus, we developed a reversion assay in a thymidine kinase deficient mutant, TX545, derived from the human ...
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An investigation using cultured human cell lines, of the involvement of vanadium, cation transport and phosphatidylinositol in the aetiology of bipolar manic depressive psychosis
... K+ FLUXES AND SODIUM PUMP NUMBERS IN LYMPHOBLASTOID CELL LINES FROM BIPOLAR MANICDEPRESSIVE PATIENTS AND CONTROL SUBJECTS; EFFECTS OF CHRONIC INCUBATION WITH OUABAIN, LITHIUM OR VANADATE[r] ...
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Isolation and characterization of cDNA clones corresponding to transcripts from the BamHI H and F regions of the Epstein-Barr virus genome.
... To characterize transcripts that are encoded in this region, polyA+ RNA from the EBV-transformed lymphoblastoid cell line JY was isolated, and this RNA was used to generate a cDNA librar[r] ...
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A second Epstein-Barr virus membrane protein (LMP2) is expressed in latent infection and colocalizes with LMP1.
... However, the documentation of LMP2 expression in almost all cells in latently infected lymphoblastoid cell lines is a necessary step in the delineation of the association of LMP2 with la[r] ...
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Autoantibodies to B Lymphocytes in a Patient with Hypoimmunoglobulinemia: CHARACTERIZATION AND PATHOGENIC ROLE
... immunodeficiency, lymphocyte counts vary between 600 and 1,000 per mm 3 with 0.5-1.5% bone marrow-derived (B) cells and 98-99% thymus-derived (T) cells. Anti-lymphocyte antibodies were detected by immunofluorescence and ...
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De novo synthesis and secretion of a 36 kD protein by cells that form lupus inclusions in response to alpha interferon
... two cell lines among 19 human lymphoblastoid cell lines tested that formed the human lupus inclusions (LI) to a high ...other cell lines were examined for protein changes that might accompany ...
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