M bovis
Regulatory, pro-inflammatory and inhibitory human T-cell responses to M. bovis BCG : opposing T-cell forces in TB-vaccination
... Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG), the only available and licensed TB-vaccine, was developed already in ...Mycobacterium bovis, a bacterium of the Mycobacterium ...
197
Disparate Host Immunity to Mycobacterium avium subsp. paratuberculosis Antigens in Calves Inoculated with M. avium subsp. paratuberculosis, M. avium subsp. avium, M. kansasii, and M. bovis
... from M. bovis-infected cattle with either a recombinant early se- cretory antigenic target 6 and culture filtrate protein 10 fusion protein (rESAT-6:CFP-10) or ...M. bovis PPD ...the M. ...
10
Use of the hupB Gene Encoding a Histone Like Protein of Mycobacterium tuberculosis as a Target for Detection and Differentiation of M tuberculosis and M bovis
... in M. bovis BCG Pasteur strain relative to ...for M. bovis BCG ...of M. bovis is ...of M. tuberculosis and M. bovis we have analyzed thus far (total tested ⫽ ...
9
Allele Specific PCR Method Based on pncAand oxyR Sequences for Distinguishing Mycobacterium bovis from Mycobacterium tuberculosis: Intraspecific M bovis pncA Sequence Polymorphism
... Primers and PCR conditions. The amplification primers for pncA and oxyR used in this study were based on previously described sequences (5, 20). For the allele-specific pncA method, the forward primer, pncATB-1.2 ...
5
Rapid Differentiation of Mycobacterium tuberculosis and M bovis by High Resolution Melt Curve Analysis
... as M. tu- berculosis and one isolate as M. bovis using the narGHJI and oxyR SNP ...The M. bovis isolate was further identified as M. bovis BCG by targeting the RD1 region ...
5
Flow Cytometric Detection of Gamma Interferon Can Effectively Discriminate Mycobacterium bovis BCG-Vaccinated Cattle from M. bovis-Infected Cattle
... Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that is increasing in incidence in United Kingdom cattle ...of M. bovis-infected animals and the potential to distinguish ...
6
Mycobacterium bovis subsp caprae Caused One Third of Human M bovis Associated Tuberculosis Cases Reported in Germany between 1999 and 2001
... Mycobacterium bovis subsp. caprae and M. bovis subsp. bovis among German tubercu- losis cases caused by the bovine tubercle bacillus from 1999 to 2001 was ...with M. bovis subsp. ...
8
Ocular mycobacteriosis—dual infection of M. tuberculosis complex with M. fortuitum and M. bovis
... Background: We report unfavorable outcome in a patient with subretinal granuloma caused by dual infection of Mycobacterium tuberculosis complex with Mycobacterium fortuitum and Mycobacterium bovis in an ...
5
Differential Live Mycobacterium tuberculosis-, M. bovis BCG-, Recombinant ESAT6-, and Culture Filtrate Protein 10-Induced Immunity in Tuberculosis
... the M. bovis BCG strain, are processed along the endosomal pathway, ac- tivating stronger responses of proinflammatory cytokines, such as TNF- ␣ , IL-2, and IL-6, than the responses activated by virulent ...
8
Inhibition of the Multiplication of Mycobacterium leprae by Vaccination with a Recombinant M. bovis BCG Strain That Secretes Major Membrane Protein II in Mice
... of M. leprae and Mycobacterium sp. strain w, and recombinant M. bovis BCG as candidate vaccines in regions of endemicity (1–4, 7, 15, 20, ...Although M. bovis BCG offered a certain ...
6
Differentiation of strains in Mycobacterium tuberculosis complex by DNA sequence polymorphisms, including rapid identification of M bovis BCG
... 23 M. bovis BCG strains were sequevar MED-C (Table ...55 M. bovis (not BCG) or 14 other ...The M. bovis (not BCG) strains included isolates from humans and cattle, strains with a ...
5
Assessment of an Oral Mycobacterium bovis BCG Vaccine and an Inactivated M. bovis Preparation for Wild Boar in Terms of Adverse Reactions, Vaccine Strain Survival, and Uptake by Nontarget Species
... Survival of M. bovis BCG. Oropharyngeal tonsil, mandibular lymph node (LN), parotid and retropharyngeal LN, lung, tracheobronchial LN, mediastinal LN, spleen, ileocecal valve, mesenteric LN, and hepatic LN ...
9
Lack of intracellular replication of M. tuberculosis and M. bovis BCG caused by delivering bacilli to lysosomes in murine brain microvascular endothelial cells
... and M. bovis BCG bacilli are eliminated via traditional endosomal-lysosomal fusion processes, we did identify a subset of Mtb bacilli that escape to the cytoplasm and may serve as a basis for persistence in ...
12
Differentiation between Mycobacterium bovis BCG-Vaccinated and M. bovis-Infected Cattle by Using Recombinant Mycobacterial Antigens
... to M. bovis and no ...the M. bovis infec- tions in the BCG-vaccinated animals were at an early stage, since two of the ...M. bovis-infected animals which had been vaccinated had ...
5
Humoral Immune Responses of White-Tailed Deer (Odocoileus virginianus) to Mycobacterium bovis BCG Vaccination and Experimental Challenge with M. bovis
... The animals in this study did not produce readily detectable antibody responses to MPB83 by immunoblotting or MAPIA. This is in contrast to the observations from previous studies with cervids in which MPB83 was found to ...
7
Development of Diagnostic Reagents To Differentiate between Mycobacterium bovis BCG Vaccination and M. bovis Infection in Cattle
... ESAT-6 and MPB64, both constituents of the diagnostic cocktails used in this study, have been tested previously in cattle. ESAT-6 has been shown to induce IFN-␥ production in 85 to 90% of the field reactors tested in ...
8
Identification of Surrogates and Correlates of Protection in Protective Immunity against Mycobacterium bovis Infection Induced in Neonatal Calves by Vaccination with M. bovis BCG Pasteur and M. bovis BCG Danish
... the M. bovis-specific antigens ESAT-6 and CFP-10 also showed a correlation be- tween extent of disease and IFN- ␥ ...to M. bovis-specific an- tigens such as ESAT-6 and CFP10 are central to ...
7
Use of Antigen-Specific Interleukin-2 To Differentiate between Cattle Vaccinated with Mycobacterium bovis BCG and Cattle Infected with M. bovis
... Mycobacterium bovis and in cattle vaccinated with Myco- bacterium bovis BCG and then experimentally challenged with pathogenic ...with M. bovis produced quantifiable levels of antigen-specific ...
7
Use of Antigen-Specific Interleukin-2 To Differentiate between Cattle Vaccinated with Mycobacterium bovis BCG and Cattle Infected with M. bovis
... either M. bovis BCG-vaccinated or uninfected controls provides the possi- bility that IL-2 could make a useful addition to the DIVA test toolbox to distinguish vaccinated from ...M. ...
7
AIM2 inhibits autophagy and IFN-β production during M. bovis infection
... To test whether the AIM2 inflammasome have an influence on autophagy in M. bovis-infected macrophages, we first knocked down the expression of AIM2 in J774A.1 murine macrophages using small interference RNA ...
16