Macrophage phenotype
Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
... on macrophage phenotype and function ...MΦ2 macrophage phenotype necessary for resolution of inflammation via a receptor- dependent ...
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Original Article Huiyang Shengji Extract improved wound healing by regulating macrophage phenotype transition
... of macrophage phenotype transition is a primary reason for wound healing failure caused by persistent ...on macrophage phenotype transition in chronic skin wound of mice and macrophages in ...
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Temporal changes in macrophage phenotype after peripheral nerve injury
... in macrophage phenotype, we also exposed BMDM to each stimulus ...vitro macrophage polarization which is “M(stimulating ...used macrophage phenotype markers, Nos2 (upregulated by ...
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Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)
... The major novel findings in this study are the reduction in M2 and increase in M1 macrophages in the airway wall of SAs in smokers and COPD. M1 are the strongest signal for innate inflammatory up-regulation we have seen ...
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Macrophage phenotype in response to ECM bioscaffolds
... and phenotype are critical determinants of the healing response following ...pro-inflammatory macrophage phenotype has been associated with the therapeutic use of bioscaffolds composed of ...
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Macrophage phenotype is associated with disease severity in preterm infants with chronic lung disease.
... immature phenotype may drive ongoing inflammation in the tissue, both via the synthesis of chemokines and enhanced activation ...correlating macrophage phenotype with cellular function ex vivo would ...
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The significance of macrophage phenotype in cancer and biomaterials
... inflammatory macrophage presence and improving the healing ...influence macrophage phenotypes, with more porous materials leading to de- creased healing time of implants and, therefore, a reduced fibrous ...
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NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis
... Lung macrophage profibrotic polarization is regulated via modulation of mitochondrial ...profibrotic phenotype, we asked whether the macrophage phenotype was dependent on mitochondrial ...
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Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
... Our present data showed that among glioblastoma-infiltrating innate immune cells, MDSCs were more dichotomous in expression of M1 and M2 markers than microglia and macrophages were. Micro- glia and macrophages that ...
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The role of HFE genotype in macrophage phenotype
... To interrogate intracellular iron handling, we assessed the expression of several key iron regulatory proteins following exposure to iron or an iron chelator. Specific- ally, we assessed the expression of L-ferritin, ...
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CD300f immunoreceptor contributes to peripheral nerve regeneration by the modulation of macrophage inflammatory phenotype
... of macrophage phenotype in WD and axonal regeneration, only a few reports [22, 23] have described the expression of M1/M2 phenotypic cell markers after nerve injury and ...adjusting macrophage ...
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CPT1a gene expression reverses the inflammatory and anti-phagocytic effect of 7-ketocholesterol in RAW264.7 macrophages
... modifies macrophage phenotype, CPT1a gene expression and phagocytosis To understand the effect of intracellular lipid content on macrophage phenotype, CPT1a expression and phago- cytosis, ...
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M2 macrophage polarisation is associated with alveolar formation during postnatal lung development
... standing macrophage phenotype and function has impli- cations for discerning and potentially enhancing their contribution to organ ...‘M2’ macrophage activation state, which is increasingly being ...
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Thesis
... tissue macrophage infiltration leading to activation of adipose inflammatory pathways (4, ...the macrophage phenotype to be discussed below ...
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Unbiased analysis of the impact of micropatterned biomaterials on macrophage behaviour provides insights beyond pre defined polarisation states
... human macrophage phenotype, activation status and ...assess macrophage behaviour we initially utilised conventional methods for determining macrophage phenotype (microscopy) and ...
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Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration
... specific macrophage phenotype is necessary for tissue regeneration and PDLSC transplantation impacted macrophage polarization in vivo, we further investigated effects of PDLSCs on subsets of ...
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Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression
... senescent phenotype with increased IL8, CXCL1, and CXCL2 ...and macrophage phenotype ...senescent phenotype of PaSCs, which in turn is ...
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FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype
... inflammatory phenotype in macrophages has not been fully ...activated macrophage phenotype and is necessary for regulating M1/M2 ...M2 phenotype, to induced IRF4 activation and this is crucial ...
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Conjugated linoleic acid induces an atheroprotective macrophage MΦ2 phenotype and limits foam cell formation
... To validate the hypothesis that transcriptional changes may influence protein expression, we also performed im- munocytochemistry of the pan-macrophage marker CD68 and of the MΦ2-type receptor MR, in HPBMCs ei- ...
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M2 macrophage is the predominant phenotype in airways inflammatory lesions in patients with granulomatosis with polyangiitis
... follicles observed in parallel with granulomatous airway inflammation and by the high frequency (94.3%) of a posi- tive ANCA test, indicating a shift towards a Th2 response [18]. Indeed, it is worth mentioning that sera ...
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