macrophage specific colony-stimulating factor
Transcriptional and posttranscriptional regulation of macrophage specific colony stimulating factor gene expression by tumor necrosis factor Involvement of arachidonic acid metabolites
... The effects of tumor necrosis factor TNF on the regulation of macrophage-specific colony stimulating factor CSF-1 gene expression have been studied in HL-60 cells during monocytic differ[r] ...
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Activities of stromal and immune cells in HPV-related cancers
... Granulocyte-macrophage colony- stimulating factor; HGF: Hepatocyte growth factor; HLA: Human leukocyte antigen; HLA-DR: Human leukocyte antigen D related; HNSCC: Head and neck squamous ...
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The changes and its significance of Th17 and Treg cells and related cytokines in patients with tuberculosis pleurisy
... macrophage colony -stimulating factor, ...with specific expres- sion of transcription factor Foxp3 and negative immune regulatory ...
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Isoforms of the granulocyte-macrophage colony-stimulating factor receptor
... The experiments described in this chapter suggest that post transcriptional mechanisms account for the reduced cell surface expression of GM-CSFRa4. The most convincing data for this is the finding that when equal ...
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Anti Granulocyte Macrophage Colony Stimulating Factor Autoantibodies Are a Risk Factor for Central Nervous System Infection by Cryptococcus gattii in Otherwise Immunocompetent Patients
... the specific mechanisms explaining this susceptibility have not been ...granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibodies in HIV-uninfected otherwise ...
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Parathyroid hormone and lipopolysaccharide induce murine osteoblast like cells to secrete a cytokine indistinguishable from granulocyte macrophage colony stimulating factor
... unknown cytokines, we have induced primary murine osteoblasts with two bone active agents, parathyroid hormone (PTH) and lipopolysaccharide (LPS) and analyzed the conditioned media (CM) for the presence of ...
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A study of the granulocyte-macrophage colony stimulating factor receptor (GM-CSFR) in leukaemia
... Although the GM-CSFR chain does not bind ligand by itself, studies have shown that the GM-CSF ligand and the chain can be crosslinked. This indicates that they are in close proximity and indeed that the p^ chain may be ...
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Adipocyte macrophage colony stimulating factor is a mediator of adipose tissue growth
... Adenoviral-mediated gene transfer of MCSF to rabbit adi- pose tissue in vivo. All animals tolerated the gene transfer procedures well. Successful transfer of b -galactosidase was de- tected in the Ad- b gal–transduced ...
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Granulocyte colony stimulating factor (G CSF) and granulocyte macrophage colony stimulating factor (GM CSF) for sepsis: a meta analysis
... antibiotic therapy and the length of hospital stay [45]. Rosen and colleagues [[44] observed a higher leukocyte count, increased mHLA-DR, and better cure/improve- ment of infection in GM-CSF group. Results from our ...
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Current status of granulocyte–macrophage colony-stimulating factor in the immunotherapy of melanoma
... In a phase 1 study, patients with subcutaneous or cu- taneous metastases from breast, gastrointestinal, head and neck, or melanoma malignancies were treated with T-VEC. Clinically stable disease was noted in 3/26 pa- ...
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The effect of myeloid growth factors on phagocyte-endothelium interactions.
... growth factor (PDGF), as well as GM-CSF, G-CSF and M-CSF (Libby et al, 1986, McIntyre et al, 1986, Fibbe et al, 1989, Zsebo et al, ...necrosis factor (IN F ) (Saegusa et al, ...
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Clinical haemopoietic implications of fucoidan treatment
... The long-term safety profile of growth-factor therapy in normal individuals has not been established. G-CSF toxicity has been defined in studies of allogeneic donors (Anderlini et al., 1996; Akizuki et al., 2000). ...
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Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate
... The sequence encoding the mature mGM-CSF protein was PCR amplified and cloned in the P. pastoris pPIC9 expression vector, in-frame with the S. cerevisiae a- mating factor prepropeptide coding sequence and under ...
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Myeloid-derived suppressor cells in hematological malignancies: friends or foes
... Granulocyte colony- stimulating factor; GM-CSF: Granulocyte-macrophage colony-stimulating fac- tor; G-PBSC: G-CSF peripheral blood stem cells harvest; GRFS: GVHD and relapse-free ...
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Expression and Secretion of Human Granulocyte Macrophage-Colony Stimulating Factor Using Escherichia coli Enterotoxin I Signal Sequence
... granulocyte macrophage-colony stimulating factor (hGM-CSF) in Escherichia coli, hGM-CSF cDNA was fused in-frame next to the signal sequence of ST toxin (ST-I) of exteroxigenic ...
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Immune-based therapies for metastatic prostate cancer: An update
... Furthermore, in a single arm phase II trial of PSA-TRICOM [PROSTVAC expressing PSA together with 3 immune-stimulating molecules (ICAM-1, B7.1 and LFA-3 by poxviral vectors and boosted using fowlpox vectors)], in ...
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An Update on Pathophysiology and Medical Management of Endometriosis
... and specific targets of growth factor inhibitor ,which have been shown to exert anti-angiogenic effects on endometriotic lesions, ...to specific receptors located on the surface membrane of ...
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Potentiation by granulocyte macrophage colony stimulating factor of lipopolysaccharide toxicity in mice
... To further investigate the role of GM-CSF in modulating LPS toxicity, we used an alternative in vivo model of septic shock, i.e., LPS-induced liver failure in GalN-sensitized mice.. NMRI[r] ...
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Effect of granulocyte macrophage colony stimulating factor in experimental visceral leishmaniasis
... GM-CSF induces three effects potentially beneficial in visceral leishmaniasis: blood monocyte mobilization, macrophage activation, and amelioration of granulocytopenia. To determine the experimental role and ...
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Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery.
... monocytes were reported to be nonpermissive for adenovirus entry (10). Moreover, following antibody-mediated entry into cells, adenovirus fails to undergo late steps in virus replication (assembly) (3). Thus, virus entry ...
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