Macular pigment
Absolute and estimated values of macular pigment optical density in young and aged Asian participants with or without age-related macular degeneration
... Background: Lutein and zeaxanthin are suggested micronutrient supplements to prevent the progression of age- related macular degeneration (AMD), a leading cause of blindness worldwide. To monitor the levels of ...
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Macular pigment response to a supplement containing meso-zeaxanthin, lutein and zeaxanthin
... Macular pigment (MP), first identified in the mid-1980s as a combination of lutein and zeaxanthin [1-3], was sub- sequently shown to be characterized by the presence of specific stereoisomers of these two ...
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Association of age and macular pigment optical density using dual-wavelength autofluorescence imaging
... There are some notable limitations in this study. First, we included a relatively small population with a preponderance of female subjects. Second, although we excluded individuals using supplements known to enhance ...
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Macular pigment spatial profiles in South Asian and white subjects
... This is the first study to investigate the prevalence of different MP spatial distributions for Asian and white subjects. Our results show that central MPOD was significantly increased in our 54 Asian subjects, compared ...
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Changes of macular pigment optical density in elderly eyes: a longitudinal analysis from the MARS study
... Results: The study participants’ mean age at baseline was 70.5 years. Early AMD was present in 150 study eyes (39.5 %) and a ring‑like distribution of MPOD was found in 87 study eyes (22.9 %). After a median follow‑up ...
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Macular pigment optical density in a Brazilian sample
... the macular pigment’s area of maximum ...of macular pigment and evaluates four variables: maximum MPOD, mean MPOD, MPOD volume, and MPOD area ...
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Preliminary analysis of the relationship between serum lutein and zeaxanthin levels and macular pigment optical density
... upper and lower limits of the gray values were defined from all 324 × 324 pixels of each FAF image. Next, we stretched the pixel values between these limits to standardize the FAF intensities for comparison. The lower ...
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Macular pigment in retinal health and disease
... [1]. Macular pigment (MP) is a generic term used to describe the yellow pigment composed principally of the three isomeric carotenoids meso-zeaxanthin (MZ), lutein (L), and zeaxanthin (Z), which ...
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Macular pigment optical density is related to blood glutathione levels in healthy individuals
... of macular pigment (MP), which is comprised of the carotenoid lutein and its isomers zeaxanthin 4 and meso- ...the macular region to short wavelength light, which is most damaging in the 440 to 460 ...
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Repeatability of the macular pigment spatial profile: A comparison of objective versus subjective classification
... of macular pigment in a healthy cohort, MP profiles of unhealthy eyes (for example in AMD or in macular telangiectasia type 2) should be considered in future ...
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Macular pigment optical density: repeatability, intereye correlation, and effect of ocular dominance
... The study was approved by the institutional review board at Western University of Health Sciences, Pomona, California, USA, and conducted in accordance with the tenets of the Declaration of Helsinki. A group of 72 ...
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The Association between Foveal Morphology and Macular Pigment Spatial Distribution: An Ethnicity Study
... A possible predictor of the MPOD spatial profile may be foveal morphology. Almost thirty years ago it was suggested that the spatial distribution of MP was attributable to its position within the individual retinal ...
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Ethnic differences in the spatial distribution of macular pigment and its association with foveal anatomy
... findings of the present study also compare favourably with another in which MPOD was measured in South Asian subjects. A mean central MPOD of 0.63 ± 0.16 in sixty South Asian subjects aged 20 to 29 years, and 0.72 ± 0.22 ...
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Computational simulation of Haidinger's brushes
... about macular pigment density [5, 15-17] and ocular retardation [16, ...that macular pigment density and distribution is affected by macular disease, and inter-observer variations in ...
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The role of the carotenoids, lutein and zeaxanthin, in protecting against age-related macular degeneration: A review based on controversial evidence
... The relation of fasting plasma levels of retinol, ascorbate, alpha-tocopherol, beta-carotene and the use of vitamin supplements has shown that alpha tocopherol, and an antioxidant index including alpha tocopherol, ...
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The spectral, spatial and contrast sensitivity of human polarization pattern perception
... of macular pigment; (ii) the change in sensitivity across the central field follows macular pigment density; (iii) polarization patterns are identifiable across a range of contrasts and ...
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An Experience in the Challenges of Research: Prevention of Age–Related Macular Degeneration, Hilary Snyder
... Tissue damage in the eye leading to AMD is primarily caused by an imbalance in a reduction–oxidation (redox) process in the cells. An excess of unstable molecules, known as free radicals, creates a chain reaction which, ...
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Lens density measurements by two independent psychophysical techniques
... The visual field produced by the instrument is shown in Fig. 3. Offset from the center at 7.5° eccentricity is a 0.5° stimulus illuminated by either a blue or green LED of peak wavelength 455 or 515 nm, respectively. The ...
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The relation between serum lipids and lutein and zeaxanthin in the serum and retina: results from cross-sectional, case-control and case study designs
... and macular region of the neural retina, where they and their isomer meso-zeaxanthin (MZ) are termed macular pigment (MP) ...age-related macular degeneration (AMD), an acquired ...
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Carotenoids concentration detection investigation: a review of current status and future trend
... natural pigment are the class of hydrocarbon and may easily found in vegetables and fruits as well as in human ...as macular pigment and skin also give high correlation and significant with plasma ...
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