Major histocompatibility complex class II
Dynamics of major histocompatibility complex class II-positive cells in the postischemic brain - influence of levodopa treatment
... MHC II: major histocompatibility complex class II; tMCAO: transient Middle cerebral artery occlusion; FACS: fluorescence-activated cell sorting; HBSS: Hank ’ s balanced salt ...
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Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency
... histocompatibility complex class II molecules. MHC class II genes transcription is regulated by four transcription factors: CIITA, RFXANK, RFX5 and ...in major ...
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Impact of Endogenous Intronic Retroviruses on Major Histocompatibility Complex Class II Diversity and Stability
... The major histocompatibility complex (MHC) represents a multigene family that is known to display allelic and gene copy number variations. Primate species such as humans, chimpanzees (Pan ...
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Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 3 Inhibits Gamma Interferon and Major Histocompatibility Complex Class II Expression
... class II. (A) Low surface expression of MHC II in PEL cells compared to KSHV-negative B cell ...MHC II transcripts upon vIRF-3 ...MHC II (HLA-DRA/B, -DPA/B, and -DQA/B) mRNA was ...
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Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice.
... Second, this study examined the role of the class II-restricted immune response in demyelinating disease. Although the pre- cise mechanism of TMEV-induced demyelination has not been determined, several ...
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A defect in the regulation of major histocompatibility complex class II gene expression in human HLA DR negative lymphocytes from patients with combined immunodeficiency syndrome
... Biosynthesis of HLA-DR alpha-chain and beta-chain is abolished in the lymphocytes of these patients and there is a total absence of mRNA for either alpha-chains or beta-chains of HLA-DR. This indicates that the lack of ...
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Herpesvirus Interference with Major Histocompatibility Complex Class II-Restricted T-Cell Activation
... HLA class II downregulation in context. The gene products mentioned may represent just the tip of the iceberg that con- stitutes the array of herpesvirus gene products with significant effects on the immune ...
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Roles of Major Histocompatibility Complex Class II in Inducing Protective Immune Responses to Influenza Vaccination
... cells, 2.2 ⫻ 10 7 enriched CD43 ⫹ cells, or 3.3 ⫻ 10 7 enriched CD43 ⫺ cells derived from wild-type mice (Fig. 7A). The groups of MHC-II KO mice that received adoptive transfer with a fraction of CD4 ⫹ , CD43 ⫹ , ...
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Regulation of major histocompatibility complex class II gene expression in trophoblast cells
... MHC class II expression is activated in mouse trophoblast cells treated with the histone deacety- lase inhibitor trichostatin A (TSA), which is a fungal prod- uct ...MHC class II molecule ...
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CD200 fusion protein decreases microglial activation in the hippocampus of aged rats
... including major histocompatibility complex Class II (MHCII) and CD40 mRNA, as well as MHCII immunoreactivity, were increased in hippocampus of aged, compared with young, rats and that ...
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T-cell recognition in experimental autoimmune thyroiditis
... four major hormonogenic sites in Tg, we demonstrated that both CH9 and ADA2 recognize an epitope containing the T4 at position 2553 in human ...by major histocompatibility complex class ...
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Cells of the synovium in rheumatoid arthritis T lymphocytes
... epitope major histocompatibility complex class II (MHCII-SE) and peptide on antigen-presenting cells (APCs) either systemically or in the ...
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A Novel Bat Herpesvirus Encodes Homologues of Major Histocompatibility Complex Classes I and II, C-Type Lectin, and a Unique Family of Immune-Related Genes
... encode major histocompatibility complex (MHC)-related proteins, 2 to encode MHC class I homologues, and 3 to encode MHC class II homologues; 4 encode the homologues of C-type ...
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Host response to Sendai virus in mice lacking class II major histocompatibility complex glycoproteins.
... class I 1 II 2 MC57G target cells were scored as positive. The addition of recom- binant IL-2 optimizes this in vitro system, but the frequency of the CTLp de- tected depends on the extent of clonal ...
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T-Cell Vaccination Alters the Course of Murine Herpesvirus 68 Infection and the Establishment of Viral Latency in Mice
... a major health concern, and there is significant interest in developing vaccines against this class of viral ...for class I- and class II-restricted epitopes on the acute phase of the ...
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Efficient Class II Major Histocompatibility Complex Presentation of Endogenously Synthesized Hepatitis C Virus Core Protein by Epstein-Barr Virus-Transformed B-Lymphoblastoid Cell Lines to CD4+ T Cells
... Hepatitis C virus (HCV) has been known as a major etio- logic agent of posttransfusion and sporadic community-ac- quired non-A, non-B hepatitis. Like the other members in the family Flaviviridae, HCV contains a ...
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Gains and Losses of HLA Class II (DR) and CD4 in Atypical Hyperplasia, Carcinoma in situ and Infiltrating Ductal Carcinoma of the Breast
... of major histocompatibility complex (MHC) class II (HLA-DR) on atypical and malignant primary mammary epithelial cells, as well as the magnitude of the stromal T lymphocytes (T4 subset) ...
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Phenotypic changes in Langerhans' cells after infection with arboviruses: a role in the immune response to epidermally acquired viral infection?
... of major histocompatibility complex class I and II antigens (4, 22, 25) and the accessory and costimulatory molecules intra- cellular adhesion molecule-1–CD54, CD11a, CD18 (6, 21), and ...
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Molecular analysis of major histocompatibility complex alleles associated with the lupus anticoagulant
... thromboses. Major histocompatibility complex (MHC) class II alleles (HLA-DR and DQ) were determined by restriction fragment length polymorphisms (RFLP) in 20 patients with APA ...
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Cytotoxic T-Lymphocyte Precursor Frequencies in BALB/c Mice after Acute Respiratory Syncytial Virus (RSV) Infection or Immunization with a Formalin-Inactivated RSV Vaccine
... study, major histocompatibility complex (MHC) class I- and II-restricted, RSV-specific cytotoxic T-lymphocyte precursor (CTLp) frequencies were determined in bronchoalveolar lavage ...
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