major histocompatibility complex molecules class I
Human Herpesvirus 7 U21 Tetramerizes To Associate with Class I Major Histocompatibility Complex Molecules
... to class I MHC molecules in immunoprecipitations of class I MHC molecules, regardless of whether immunoprecipitations were performed from metabolically labeled lysates of ...
11
Targeted infection of human cells via major histocompatibility complex class I molecules by Moloney murine leukemia virus-derived viruses displaying single-chain antibody fragment-envelope fusion proteins.
... Thanks to genetic engineering of the env-encoded glycopro- tein, successful redefinition of retroviral infection specificity has recently been obtained. (i) Replacement of an internal region of the envelope ...
6
Downregulation of Major Histocompatibility Complex Class I Molecules by Kaposi's Sarcoma-Associated Herpesvirus K3 and K5 Proteins
... I molecules by K3 and K5, BJAB cells were used to establish cell lines stably expressing the K3, ...MHC class I surface expression by flow ...MHC class I mol- ecules on their ...
10
Murine Cytomegalovirus Perturbs Endosomal Trafficking of Major Histocompatibility Complex Class I Molecules in the Early Phase of Infection
... MHC-I molecules are retained in a perinuclear early endosomal compartment that is insensitive to brefeldin ...MHC-I molecules either do not reach or do not stay long in the predegradative ...
12
Physical Association of the K3 Protein of Gamma-2 Herpesvirus 68 with Major Histocompatibility Complex Class I Molecules with Impaired Peptide and β2-Microglobulin Assembly
... the class I heavy chain at a junction between the peptide binding region and the ␣3 domain, a unique interaction site distinct from known ER chaperone binding ...
8
Role of the adenovirus E3-19k conserved region in binding major histocompatibility complex class I molecules.
... 4778-4783 0022-538X/92/084778-06$02.00/0 Copyright © 1992, American Society for Microbiology Role of the Adenovirus E3-19k Conserved Region in Binding Major Histocompatibility Complex Cl[r] ...
6
Cellular and Molecular Requirements for Association of the Murine Cytomegalovirus Protein m4/gp34 with Major Histocompatibility Complex Class I Molecules
... MHC class I levels and is found bound to class I molecules at the cell surface (10, 13, ...m4/gp34-MHC class I com- plexes at the cell surface may have other consequences, ...
8
Structural and Functional Dissection of Human Cytomegalovirus US3 in Binding Major Histocompatibility Complex Class I Molecules
... type I transmembrane proteins has also been characterized as an ER retention signal (20, ...MHC class I molecules, thereby interfering with their cell surface ...
8
GRP78, a Coreceptor for Coxsackievirus A9, Interacts with Major Histocompatibility Complex Class I Molecules Which Mediate Virus Internalization
... GRP78, a receptor for CAV-9. It has been known that CAV-9 forms a detergent-stable complex with a 70-kDa MHC- I-associated cell surface protein (MAP-70) (31). Virus-recep- tor complexes were isolated and ...
11
The role of major histocompatibility complex molecules in luteal function
... of class I and class II MHC molecules on the surface of a cell allows the cell to interact with CD8+ and CD4+ T lymphocytes, ...MHC molecules to the TCR can occur in the absence of ...
7
The Lytic Cycle of Epstein-Barr Virus Is Associated with Decreased Expression of Cell Surface Major Histocompatibility Complex Class I and Class II Molecules
... surface major histocompatibility complex (MHC) and immunostimulatory molecules required for recognition and lysis by virus-specific cytotoxic T ...MHC class I molecules ...
10
Analysis of Pigtail Macaque Major Histocompatibility Complex Class I Molecules Presenting Immunodominant Simian Immunodeficiency Virus Epitopes
... MHC class I alleles. Up to 96 MHC class I cDNA clones from six pigtail macaques underwent forward and reverse sequencing, generating 700- to 1,000-bp ...
12
Definition of Five New Simian Immunodeficiency Virus Cytotoxic T-Lymphocyte Epitopes and Their Restricting Major Histocompatibility Complex Class I Molecules: Evidence for an Influence on Disease Progression
... MHC class I alleles to disease ...MHC class I haplotypes among five Mamu-DRB-identical offspring in an extended family of rhesus ...MHC class I haplotypes of the intermediate and ...
11
Zika Virus Escapes NK Cell Detection by Upregulating Major Histocompatibility Complex Class I Molecules
... type I IFNs and downstream interferon-stimulated genes ...type I interferon response in human placental macrophages and placental tissues (48, FIG 6 Zika virus sensing is mediated by IRF3 and ...MHC ...
11
The Major Histocompatibility Complex Class I Genes of Zebrafish.
... 100 class I genes to be characterized due to their nonclassical function and thus their decreased likelihood of being critical determinants of transplant ...L molecules perform functions other than ...
156
Vesicular stomatitis virus infection of the central nervous system activates both innate and acquired immunity.
... of major histocompatibility complex (MHC) class I molecules on astrocytes and microglial, endothelial, and ependymal cells was also rapidly induced and followed by induced ...
7
Selective Downregulation of Rhesus Macaque and Sooty Mangabey Major Histocompatibility Complex Class I Molecules by Nef Alleles of Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2
... MHC class I ...MHC class I molecules were aligned to the cytoplasmic domain sequence of ...MHC class I tail sequences indicated in bold type were selected for analysis of ...
8
Conditional CD8+ T Cell Escape during Acute Simian Immunodeficiency Virus Infection
... to major histocompatibility complex class I (MHC class I) molecules, impair T cell receptor recognition, or diminish the efficiency of epitope processing begin to ...
5
A Human Herpesvirus 7 Glycoprotein, U21, Diverts Major Histocompatibility Complex Class I Molecules to Lysosomes
... MHC class I molecules to ...of class I mole- cules complexed with ...Ab. Class I immunolabeling of control astrocytoma cells shows a typical plasma membrane labeling ...
12
Human Cytomegalovirus-Encoded Immune Modulators Partner To Downregulate Major Histocompatibility Complex Class I Molecules
... implies that in the presence of US3, various alleles of class I protein could become substrates for US2-mediated degra- dation. This is in agreement with previous findings describ- ing allele-specific ...
9