mammalian genomes
Vanishing GC-Rich Isochores in Mammalian Genomes
... within mammalian genomes—we analyzed the synonymous substitution pattern in coding sequences from closely related species in different mammalian ...
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Comparison of carnivore, omnivore, and herbivore mammalian genomes with a new leopard assembly
... If adaptive evolution affects only a few crucial amino acids over a short time period, none of the methods for measuring selection is likely to succeed in defining positive selection [45]. Therefore, we in- vestigated ...
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Global expression mapping of mammalian genomes
... cDNA clones. By this method it was found that 75% o f clones did not share their top 1% n ei g hbo ur ho od reciprocally with any other clone. That is, 75% of clones remained as singletons. Data from agarose gels ...
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How many antiviral small interfering RNAs may be encoded by the mammalian genomes?
... Presentation of the hypothesis: It was found that >50% of the human genome is transcribed in different cell types and that these transcripts are mainly not associated with known protein coding genes, but represent ...
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GC-Content Evolution in Mammalian Genomes: The Biased Gene Conversion Hypothesis
... Bird genomes regions (which do not; De Bry and Marzluff ...than mammalian GC-rich regions (Kadi et Hotspots of recombination should also become GC ...
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Rapid generation of long tandem DNA repeat arrays by homologous recombination in yeast to study their function in mammalian genomes
... gene expression studies to protect transgenes from epi- genetic gene silencing. In addition, amplified repeats are also important for experiments on epigenetic engineer- ing. The principle of this approach is based on ...
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Clusters of co expressed genes in mammalian genomes are conserved by natural selection
... 2000). These co-expressed genes cannot be operons, because the two genes often occur on opposite strands of DNA, mak- ing polycistronic transcription impossible (Cohen et al., 2000). The same co-expression of neighboring ...
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The impact of epigenetic factors on nucleotide substitution patterns in mammalian genomes
... Different CpG m utation and selection properties between primates and yeast are apparent, generally consistent with the expected outcomes from methylated and non-methylated genomes. If there is no impact from ...
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A Comparative Study and a Phylogenetic Exploration of the Compositional Architectures of Mammalian Nuclear Genomes
... of mammalian genomes is the uniformity of GC content over hundreds and hundreds of thousands base-pairs termed short- and long-range correlations, ...the mammalian genome is composed of a mosaic of ...
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Distribution, Diversity, and Evolution of Endogenous Retroviruses in Perissodactyl Genomes
... of mammalian genomes has been shaped by interactions with endogenous retroviruses ...the mammalian order Perissodactyla, with a view to under- standing their impact on the evolution of modern equids ...
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A subset of conserved mammalian long non coding RNAs are fossils of ancestral protein coding genes
... mammalian genomes yet are present in other verte- brates. We focused on species with relatively high- quality genome assemblies, including eight mammals (human, rhesus, marmoset, mouse, rabbit, dog, sheep, ...
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A Novel Recombinant Retrovirus in the Genomes of Modern Birds Combines Features of Avian and Mammalian Retroviruses
... the genomes of vertebrate spe- ...than mammalian genomes (⬃8%, com- pared to ⬃45% for mammals), zebra finches have approximately three times the number of ERV-related sequences as chickens, a ...
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Comprehensive genomic analysis reveals dynamic evolution of endogenous retroviruses that code for retroviral-like protein domains
... potential in mammalian genomes, we comprehensively ex- amined ERV-ORFs in 19 mammalian species. We previ- ously developed a database called gEVE (http://geve.med. u-tokai.ac.jp) containing 176,401 ...
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Horizontal transfers of Mariner transposons between mammals and insects
... the mammalian genomes (Table ...marsupial genomes, including Macropus euge- nii, Monodelphis domestica, and Sarcophilus harrisii (Figure ...Therefore, mammalian TIGGER1 families likely ...
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Identification and characterization of diverse groups of endogenous retroviruses in felids
... Although our data suggest that cats acquired Gamma- like retroviruses during multiple cross-species transmis- sion events in the past, the exact origin of these proviruses cannot be strictly deduced based on current ...
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Genome-Wide Characterization of Endogenous Retroviruses in the Bat Myotis lucifugus Reveals Recent and Diverse Infections
... An important motivation for our analysis of ERVs in M. lucifu- gus relates to recent findings of massive lineage-specific DNA transposon activity in M. lucifugus (Fig. 3b) (59, 60). There is strong evidence that several ...
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Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis
... to mammalian genomes, bird genomes contain a low number of CNVs ...bird genomes mirror the low number of chro- mosomal rearrangements in this phylogenetic ...
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Original Article Comparison of LncRNA profile in mouse models of drug-induced liver injury and autoimmnue hepatitis
... known, mammalian genomes transcribe a broad spectrum of RNA molecules, including the classical long proteincoding mRNAs, some short regulatory noncoding RNAs ...
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Extensive intron gain in the ancestor of placental mammals
... the mammalian genomes are now available as low-coverage (~2×) ...these genomes can still have surprising effects for apparent lineage-specific insertions of ...
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Mobile genetic elements and genome evolution 2014
... the genomes of eight different hiPSC lines generated by Sleeping Beauty or lentiviral-based introduction of repro- gramming genes, for the presence of endogenous de novo retrotransposition events that were absent ...
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