Mammary development during pregnancy
Selective segregation of DNA strands persists in long label retaining mammary cells during pregnancy
... the mammary gland are positioned in basal and suprabasal positions in the ducts and alveoli ...These mammary stem/progenitor cells are undifferen- tiated pale cells that are characterized by a lack of ...
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The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis
... the mammary microenvironment during pregnancy as well as the microenvironment of the adipose tissue associated with obesity reveals similarities that may account for these parallels (Table ...the ...
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Evidence for a multipotent mammary progenitor with pregnancy specific activity
... a pregnancy-activated multipotent progenitor. By studying mammary development in MMTVrtTA/H2BGFP transgenic mice, we discovered a subset of CD24 + /CD29 lo cells possessing the unique abil- ity to ...
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Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland
... of pregnancy before food intake recovered in later ...animals during lactation although total calories consumed were iden- tical in both ...tissue during lactation than their lean ...alveolar ...
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Impact of exposure to diesel exhaust during pregnancy on mammary gland development and milk composition in the rabbit
... isoforms during early ...fumes during pregnancy at urban pollution levels can influ- ence lipid metabolism in the mammary gland and the lipid and protein composition of ...
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ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation
... Discussion We demonstrate here, using aMEC-specific ErbB3 abla- tion, that ErbB3 engages two key molecular signaling pathways at mid-pregnancy in the mammary gland, STAT5A and PI3K/Akt, which regulate two ...
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Relationship between mammary gland structures during pregnancy and breast-feeding
... between mammary gland structure and breast milk production, breast-feeding- only nursing was conducted most efficiently in the type 1 group, which demonstrated significant development in mammary ...
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A model to describe growth patterns of the mammary gland during pregnancy and lactation
... describe mammary growth patterns throughout pregnancy and ...The mammary gland is the target of several growth factors including mito- gens, such as IGF-I and epidermal growth factor (31, 38), as ...
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Oxybenzone Alters Mammary Gland Morphology in Mice Exposed During Pregnancy and Lactation
... occur during development but not ...the mammary gland in mice exposed during pregnancy and ...from pregnancy day 0 until ...evaluated. Mammary glands were collected 5 ...
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NEW INSIGHTS OF MAMMARY GLAND DURING DIFFERENT STAGES OF DEVELOPMENT
... The mammary epithelial cells proliferate, differentiate, undergo apoptosis, and tissue remodeling following a cyclic pathway in lactation – involution – lactation cycle, thus fine tuning the molecular events ...
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Epigenomics of mammary gland development
... the mammary gland back to the virgin state [1, 2]. The mammary ductal epithelium is comprised of two main cell lineages: the inner luminal population contain- ing ductal and alveolar cells, and the outer ...
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Remodeling mechanisms of the mammary gland during involution
... The development of the mammary gland occurs in three distinct phases: during embryogenesis, puberty and ...to pregnancy, tertiary branching and formation of lobuloalveolar structures is ...
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Atrazine and rat mammary gland development
... delay pregnancy-related mammary gland differentiation in a manner similar to that observed in the offspring leading to under- developed glands as pregnancy ...of pregnancy and begins to ...
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PER2 regulation of mammary gland development
... that PER2, PER1 and CLOCK have little overlap amongst their transcription targets, and thus suggests that these differential targets are crucial to functions outside of time-keeping duties (Koike et al., 2012). MaSC ...
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Age- and Pregnancy-Associated DNA Methylation Changes in Mammary Epithelial Cells
... Postnatal mammary gland development and differentiation occur during puberty and ...that pregnancy had the most significant effects on CD24 + CD61 + CD29 hi and CD24 + CD61 + CD29 lo cells, ...
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Key stages in mammary gland development: The mammary end bud as a motile organ
... In the rodent, epithelial end buds define the tips of elongating mammary ducts. These highly motile structures undergo repeated dichotomous branching as they aggressively advance through fatty stroma and, turning ...
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ER and PR signaling nodes during mammary gland development
... postnatal mammary gland development and are implicated in breast ...of mammary epithelial cells and relegate biological functions to paracrine ...
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Amphiregulin mediates progesterone induced mammary ductal development during puberty
... E+P. Mammary glands from these mice were analyzed for changes in morphology, proliferation, and expression of the downstream targets amphiregulin (AREG) and receptor activator of NF- B ligand ...in mammary ...
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Pregnancy induced changes in cell fate in the mammary gland
... term pregnancy can be accurately reproduced in rodents has lead to the development of defined animal models for studying this parity-related ...govern pregnancy-specific developmental changes in the ...
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Elucidating the Role of Spy1A during c-Myc Induced Mammary Tumor Development
... on mammary development and ...epithelial mammary tumor cells to basal levels observed in mammary development may restore the underlying TEB developmental program that has been initially ...
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