mammary epithelial
Innate defense capability of challenged primary bovine mammary epithelial cells after an induced negative energy balance in vivo
... Staphylococcus aureus (S. aureus) is among the most prevalent gram-positive bacteria causing a chronical and subclinical form of mastitis (Wellnitz et al., 2006; Tesfaye et al., 2009). Under practical conditions most ...
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KISS1R Induces Human Mammary Epithelial Cell Invasiveness and Promotes Breast Cancer Cell Migration and Invasion via IQGAP1
... human mammary epithelial MCF10A cells and moderately invasive SKBR3 stably expressing either FLAG-KISS1R or pFLAG-A1 (vector control), to form organotypic invasive structures in 3D invasion assay was ...
140
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial mesenchymal transition
... Six1-overexpressing mammary glands exhibit stem/progenitor cell ...of mammary epithelial cells harvested from sucrose-treated, nul- liparous TOSix animals (4922 and 6239 lines) and MTB animals aged ...
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Cytogenetic characterization and H-ras associated transformation of immortalized human mammary epithelial cells
... Immortalization is a key step in malignant transforma- tion, as it allows a cell to indefinitely proliferate while accumulating genetic abnormalities. Normal human mammary epithelial cells (HMEC) initially ...
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Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells.
... To determine the biological consequences of activated int-3 expression on mammary epithelial cells, we transfected the HC11 mouse mammary epithelial cell line 4 with a genomic DNA fragme[r] ...
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Contribution of mammary epithelial cells to the immune response during early stages of a bacterial infection to Staphylococcus aureus
... intra mammary infection (IMI) were selected and housed at Centro Zootecnico Didattico Sperimentale of Facoltà of MedicinaVeterinaria (Università degli studi di ...
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Tyrosine kinase signalling in breast cancer: Tyrosine kinase mediated signal transduction in transgenic mouse models of human breast cancer
... studies. Mammary epithelial expression of mutant PyV mT decoupled from the PI-3K pathway results in the induction of extensive mammary epithelial hyperplasias ...these mammary ...
6
PubMedCentral-PMC4972522.pdf
... We obtained human gene expression arrays of our engineered cell lines (GFP-HMEC, EBV-HMECsand GFP-MEC-R, EBV-MEC-R) and the tu- mors derived from GFP-HMEC-R or EBV-HMEC-R. Within each category, cell lines or tumors, we ...
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Epithelial vimentin plays a functional role in mammary gland development
... the mammary gland, vimentin intermediate filaments are expressed in stromal cells and in basal epithelial cell populations, including gland- reconstituting mammary stem cells, with largely undefined ...
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PER2 regulation of mammary gland development
... mouse mammary gland development. PER2 is highly expressed in virgin mammary glands and undifferentiated mammary epithelial cells (MECs), whereas PER1 expression is highest in lactating mouse ...
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Cancer stem cells and oral cancer: insights into molecular mechanisms and therapeutic approaches
... EMT: Epithelial-mesenchymal transition; ESA: Epithelial-specific antigen; iPSCs: Induced pluripotent stem cells; JAG1: Jagged 1; HMLEs: Human mammary epithelial cells; HNSCC: Head and [r] ...
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Gains and Losses of HLA Class II (DR) and CD4 in Atypical Hyperplasia, Carcinoma in situ and Infiltrating Ductal Carcinoma of the Breast
... the epithelial expression of major histocompatibility complex (MHC) class II (HLA-DR) on atypical and malignant primary mammary epithelial cells, as well as the magnitude of the stromal T lymphocytes ...
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Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection
... Bovine mammary epithelial cells (MEC) is a good model system to study host immune response during bacteria-induced mastitis, but recent reports have shown that it poorly mimics whole animal data ...host ...
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Ingestion and killing of Listeria monocytogenes by blood and milk phagocytes from mastitic and normal cattle
... monocytogenes 3, 7, 22, 29, 34 and the phagocytic ability of the bovine mammary epithelium 5 suggest that invasion of mammary epithelial cells by listeriae may play some part in the path[r] ...
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Transforming growth factor β and breast cancer: Cell cycle arrest by transforming growth factor β and its disruption in cancer
... Keywords: breast cancer, cell cycle, cyclin-dependent kinase inhibitor, human mammary epithelial cells, transforming growth factor-β.. Introduction TGF-β is a potent inhibitor of mammary[r] ...
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Claudin 7 expression and localization in the normal murine mammary gland and murine mammary tumors
... of mammary and renal epithelial cells [7] suggests that claudins might have functions other than the regulation of tight-junction perme- ...in mammary, airway, and renal epithelial ...the ...
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Key stages in mammary gland development: The mammary end bud as a motile organ
... the mammary stroma also caused accelerated ductal growth during puberty, confirming the stromal target for TGF- β ...factor. Mammary hepatocyte growth factor is negatively regulated by TGF- β and its ...
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Uptake of DNA by cancer cells without a transfection reagent
... human mammary epithelial cells), NHBE (human bronchial epithelial cell), NMBC (nuclear matrix breast cancer), BEP2D (immortalized human bronchial epithelial cell), HM-hT ...
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CCAAT/Enhancer Binding Protein-delta (C/EBP-delta) regulates cell growth, migration and differentiation
... and mammary tumorigenesis has also been demonstrated in mammary tumor prone MMTV/c-neu transgenic mice and rodent carcinogen-induced mammary tumors, indicating that reduced C/EBP δ expression is ...
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Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland
... embryonic mammary bud were bi-potential in terms of their lineage marker ...and mammary buds expressed the myoe- pithelial markers, K14 and p63, as well as the luminal markers, Gata3 and ...specific ...
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