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Mammary Stem Cells

Mammary stem cells: expansion and animal productivity

Mammary stem cells: expansion and animal productivity

... epithelial cells (LRECs) are stem cells identified in various organs, including murine and bovine mammary glands ...− cells), similar to mammary stem cells ...

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Mouse mammary stem cells express prognostic markers for triple negative breast cancer

Mouse mammary stem cells express prognostic markers for triple negative breast cancer

... The mammary epithelium consists of two main layers, the luminal and basal ...ER- cells (mainly proliferative progenitors) and ER+ cells (mainly non-proliferative differentiated ...myoepithelial ...

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Mammary stem cells, self renewal pathways, and carcinogenesis

Mammary stem cells, self renewal pathways, and carcinogenesis

... the cells that serve as targets of ...the stem cell as the cell of ...progenitor cells. The transformation of progenitor cells might require mutations that allow them to undergo self-renewal, ...

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Role of Notch signaling in cell fate determination of human mammary stem/progenitor cells

Role of Notch signaling in cell fate determination of human mammary stem/progenitor cells

... of mammary stem cells and on lineage commitment of mammary progenitor cells Effect of modulators of Notch signaling on self-renewal of mammary stem cells and on ...

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New insights into lineage restriction of mammary gland epithelium using parity identified mammary epithelial cells

New insights into lineage restriction of mammary gland epithelium using parity identified mammary epithelial cells

... of stem or progenitor cells that upon asymmetric cell division undergo a process of lineage restriction to generate the different epithelial cell types therein ...in mammary epithelium has long been ...

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Prolactin stimulation affects the stem cell dependent mammary repopulating ability of embryonic mammary anlagen

Prolactin stimulation affects the stem cell dependent mammary repopulating ability of embryonic mammary anlagen

... in mammary gland development and lactation has been demonstrated in previous ...on mammary duct morphogenesis at mammary anlagen stage ...of mammary cells or tissue is an effective ...

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Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts

Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts

... cleared mammary fat pads transplanted with ductal frag- ments or dispersed mammary ...identify mammary stem cells and to study their ...fluid cells (AFs) that became adherent ...

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Functional and molecular characterisation of mammary side population cells

Functional and molecular characterisation of mammary side population cells

... SP cells were pure mammary stem cells, it might be expected that they would be highly enriched for the ability to repopulate the fat pad following transplantation, as has been shown for ...

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Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland

Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland

... vidual cells may be due to the presence of labeled cells that differentiated and exited the cell-cycle shortly after the label was administered or may represent quiescent cells that divide ...

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Oncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulation

Oncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulation

... CDβGeo cells in vitro promotes EMT that is sustained after withdrawal (designated pTD cells) and transforms these mammary epithelial cells such that they become mesencymal-like and highly ...

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Towards an integrated model for breast cancer etiology: The crucial role of the number of mammary tissue specific stem cells

Towards an integrated model for breast cancer etiology: The crucial role of the number of mammary tissue specific stem cells

... of mammary tissue- specific stem cells as the core determinant of breast cancer ...when stem cells in general, and tissue-specific stem cells in particular, are ...of ...

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MicroRNA 205 signaling regulates mammary stem cell fate and tumorigenesis

MicroRNA 205 signaling regulates mammary stem cell fate and tumorigenesis

... mouse mammary stem cells, and loss of p53 led to uniform redistribution of NUMB around the cell cortex of the dividing stem cell, increased the replicative potential of the mammospheres, and ...

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Re evaluation of mammary stem cell biology based on in vivotransplantation

Re evaluation of mammary stem cell biology based on in vivotransplantation

... in mammary developmental biology and mammary neoplastic progression, and further to suggest biological events wherein our current level of ignorance could be addressed through thoughtful ...in ...

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Mammary gland stem cells: current status and future challenges

Mammary gland stem cells: current status and future challenges

... on stem cell properties of mammary SP-cells (Matulka et ...these cells still remains ...the stem cell properties of LRCs, and have somewhat surprisingly revealed that a large part of ...

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Integrin Rac signalling for mammary epithelial stem cell self renewal

Integrin Rac signalling for mammary epithelial stem cell self renewal

... assays, cells were grown at a clonal density of 2 × 10 3 cells/cm 2 in 24-well ultra-low attachment plates that had been coated with ...The cells were grown in media containing EPiCult-B media ...

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Skeletal stem cells

Skeletal stem cells

... mesenchymal stem cells ’ is not just a matter of ...mesenchymal stem cells ’ (MSCs), currently used to denote cultures of fibroblastic cells from virtually every tissue or organ (da ...

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Circulating hematopoietic stem cells and putative intestinal stem cells in coeliac disease

Circulating hematopoietic stem cells and putative intestinal stem cells in coeliac disease

... BM-derived stem cells might participate in the enteric repair process at the very begin- ning of the dietary intervention, when the local ISC niche is ...

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Comparative Biology of Glioma Stem Cells and Embryonic Neural Stem Cells in Dogs.

Comparative Biology of Glioma Stem Cells and Embryonic Neural Stem Cells in Dogs.

... xenograft-derived cells, and without pre-selection of any putative GSC subpopulations, implies that the relationship between the percentage of GSC per tumor, tumor latency and degree of malignancy is an inherent ...

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Hematopoietic Stem Cells

Hematopoietic Stem Cells

... Hematopoietic stem cell transplants permit the study of the complete reconstitution of the hematopoietic and immunologic ...system. Stem cell trans- plants are often used to treat severe aplastic anemia or, ...

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Mesenchymal Stem Cells

Mesenchymal Stem Cells

... Mesenchymal Stem Cells (MSC), also termed Mesenchymal Stromal Cells, are self-renewing multipotent cells that can differentiate into a wide variety of cell ...islets cells. They can ...

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