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matrix stiffness

Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation

Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation

... between matrix stiffness and pre-metastatic niche in ...higher matrix stiffness forces the expression of LOX in HCC as described previously [16], it remains largely un- known that which member ...

12

Collagen matrix stiffness influences on fibroblast contraction force

Collagen matrix stiffness influences on fibroblast contraction force

... collagen matrix normally exhibits a noticeable reduction in ...of matrix stiffness needs to be considered in the determination of cellular contraction forces ...the stiffness of collagen ...

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Higher matrix stiffness as an independent initiator triggers epithelial-mesenchymal transition and facilitates HCC metastasis

Higher matrix stiffness as an independent initiator triggers epithelial-mesenchymal transition and facilitates HCC metastasis

... that stiffness-induced malignant phenotypes re- sembled as that of tumor cells undergoing EMT, we speculated that higher matrix stiffness might trigger EMT and facilitate HCC ...higher ...

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Regulation Of The Human Vascular Smooth Muscle Cell Transcriptome By Extracellular Matrix Stiffness

Regulation Of The Human Vascular Smooth Muscle Cell Transcriptome By Extracellular Matrix Stiffness

... arterial matrix stiffness, an important clinical parameter for disease, but also an important mechanical property dictating cellular ...how matrix stiffness regulated the transcriptional ...

157

Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells

Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells

... Matrix stiffness as an important physical attribute of extracellular matrix exerts significant impacts on biological behaviors of cancer cells such as growth, proliferation, motility, metabolism and ...

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Matrix Stiffness and Colorectal Cancer

<p>Matrix Stiffness and Colorectal Cancer</p>

... metastasis. Matrix stiffness, one of the sources of mechanical stimulation, affects tumor cells as well as non-tumor cells in multiple different molecular signaling pathways in solid tumors such as ...

9

Mechanism of regulation of stem cell differentiation by matrix stiffness

Mechanism of regulation of stem cell differentiation by matrix stiffness

... substrate stiffness into elec- trical and calcium signals followed by the phosphoryl- ation of MLCK, causing the reorganization of the actin cytoskeleton ...these matrix stiffness- induced changes in ...

11

The Matrix Stiffness Method for 2D Trusses

The Matrix Stiffness Method for 2D Trusses

... structural stiffness matrix is a square, symmetric matrix with dimension equal to the number of degrees of ...structural stiffness matrix using terms from the element stiffness ...

8

Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5

Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5

... lular matrix (ECM)), soluble cytokines, and growth fac- tors ...s stiffness [5], which is one of the several factors that contribute to wide variations in the rigidity of human tissues and organs ...the ...

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Lymphangiogenesis in Breast Cancer Correlates with Matrix Stiffness on Shear Wave Elastography

Lymphangiogenesis in Breast Cancer Correlates with Matrix Stiffness on Shear Wave Elastography

... Tumor stiffness was quantitatively measured by shear-wave elastography in preoperative ultrasound examination, calculated as mean elasticity value ...tumor stiffness, and clinicopathologic data were ...

7

Bone marrow CD34+ cell subset under induction of moderate stiffness of extracellular matrix after myocardial infarction facilitated endothelial lineage commitment in vitro

Bone marrow CD34+ cell subset under induction of moderate stiffness of extracellular matrix after myocardial infarction facilitated endothelial lineage commitment in vitro

... extracellular matrix (ECM), such as stiffness, regulate stem cell adhesion, proliferation, migration, differentiation, and fate [5 – ...tissue stiffness changes from flexible to rigid in a ...

15

Gender-related differences in the progression of carotid stiffness with age and in the influence of risk factors on carotid stiffness

Gender-related differences in the progression of carotid stiffness with age and in the influence of risk factors on carotid stiffness

... carotid stiffness were age, blood pressure components (pulse pressure and mean arterial pressure), type 2 diabetes mellitus and heart ...carotid stiffness and pulse pressure was observed only in women and ...

9

Understanding the patient experience of stiffness, and developing a stiffness patient recorded outcome measure in rheumatoid arthritis

Understanding the patient experience of stiffness, and developing a stiffness patient recorded outcome measure in rheumatoid arthritis

... between stiffness and pain was discussed across all focus groups, particularly in relation to the specificity of ...suggested stiffness-pain interdependence based on the results of a qualitative focus group ...

525

Stiffness in total knee arthroplasty

Stiffness in total knee arthroplasty

... The problem of joint-line level is still debated. Epicondiles are a good anatomical reference in joint-line restoration as described by Griffin. In unaffected knees, the medial epicondile is 27.4 ± 2.9 and 29.7 ± 2.7 mm ...

8

Arterial stiffness in hematologic malignancies

Arterial stiffness in hematologic malignancies

... arterial stiffness, indicating risk of premature atherosclerosis and cardiovascular disorders, and efforts should be directed in order to early identify, monitor and manage cardiovascular risk factors in these ...

8

Nanoscale Stiffness Distribution in Bone Metastasis

Nanoscale Stiffness Distribution in Bone Metastasis

... stiffness with metastasis and the effect of the treatment on this nanomechanical distribution. The distribution of elastic modulus highlights the major decrease of elastic modulus in bone with metastasis (see ...

10

Determinants of arterial stiffness in COPD

Determinants of arterial stiffness in COPD

... arterial stiffness, and this reduction is greatest in those with the highest stiffness ...arterial stiffness in COPD, [10] but in another study there was no relation between C-reactive protein and ...

7

Muscle stiffness and soreness following exercise

Muscle stiffness and soreness following exercise

... It is important to remember* that tire adaptation that occurs following DOMS is specific to a particular activity or movement. That is, if an individual suffers from DOMS following one type of exercise, this wül not ...

196

THE STIFFNESS OF THE PILLARS OF REAL BRIDGE STRUCTURES

THE STIFFNESS OF THE PILLARS OF REAL BRIDGE STRUCTURES

... В статье рассмотрен вопрос определения реальной жесткости мостовых опор и необходимости в некото - рых случаях при расчете собственных частот мостовых конструкций заменить абсолютно жест[r] ...

7

HIV is an independent predictor of aortic stiffness

HIV is an independent predictor of aortic stiffness

... arterial stiffness that has not only been shown to be predictive of both cardiovascular events and mortality in multiple population studies, [14,15] but is also a well-validated surrogate marker of atheroscler- ...

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