Mature Dendritic Cells
Varicella-Zoster Virus Productively Infects Mature Dendritic Cells and Alters Their Immune Function
... Mature dendritic cells (DCs) are potent antigen-presenting cells essential for initiating successful antiviral immune responses and would therefore serve as an ideal target for viruses seeking ...
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Development of a new protocol for 2-day generation of mature dendritic cells from human monocytes
... to cells incubated with GM-CSF plus IL-4 alone, stimulated FastDC showed increased FSC/SSC intensity; moDCs showed an even greater increase in FSC/SSC ...above, cells incubated with GM-CSF plus IL-4 alone ...
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Preferential Infection of Mature Dendritic Cells by Mouse Hepatitis Virus Strain JHM
... culture, cells were infected with MHV-JHM at an MOI of 1 and fixed at 7 to 9 h ...p.i. Cells were stained for CD11c (red) and N protein ...⫹ cells by using magnetic beads prior to infection with ...
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Rapid generation of broad T cell immunity in humans after a single injection of mature dendritic cells
... in cells that bound MHC tetramers and killed ...of mature DCs, which are the most potent APCs in vitro (22), or maybe the subcutaneous route of administration, in contrast to other reports that have used ...
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Functionally Distinct Transmission of Human Immunodeficiency Virus Type 1 Mediated by Immature and Mature Dendritic Cells
... Dendritic cells (DCs) potently stimulate the transmission of human immunodeficiency virus type 1 (HIV-1) to CD4 ⴙ T ...become mature DCs (mDCs) for effective antigen ...target cells ...
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Implication of scavenger receptors in the interactions between diesel exhaust particles and immature or mature dendritic cells
... Airway mucosa represents the first line of defence against invading airborne pathogens and particulate matters. A high level of airborne particulate matters within the inspired air is associated with an increased ...
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Mature dendritic cells correlate with favorable immune infiltrate and improved prognosis in ovarian carcinoma patients
... T cells in DC-LAMP Hi HGSCs as compared to their DC-LAMP Lo counterparts (p = ...T cells found in the HGSC TME, we employed flow cytometry on tumors freshly resected from a prospective cohort of 20 HGSC ...
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Mature Dendritic Cells Infected with Canarypox Virus Elicit Strong Anti-Human Immunodeficiency Virus CD8+and CD4+ T-Cell Responses from Chronically Infected Individuals
... T cells (4). Mature DCs are generated from immature DCs after the addition of maturation stimuli such as a MCM, lipopolysaccharide or CD40 ligand ...im- mature or mature DCs with can-HIV or ...
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The infectious synapse formed between mature dendritic cells and CD4+T cells is independent of the presence of the HIV 1 envelope glycoprotein
... T cells triggers actin-dependent recruitment of HIV-1 receptors and ad- hesion molecules to the contact interface, thus stabilizing the adhesive interactions and enabling the final transfer of HIV-1 to the target ...
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Influence of synthetic superparamagnetic iron oxide on dendritic cells
... of dendritic cells, the capacities of antigen- processing, presenting, and naive allogeneic T cells stimulated by dendritic cells were tested by a mixed leukocyte reaction ...that ...
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Immune cell profile of sentinel lymph nodes in patients with malignant melanoma – FOXP3+ cell density in cases with positive sentinel node status is associated with unfavorable clinical outcome
... + mature DCs, CD123 + plasmacytoid DCs and OX40 + activated T cells in sentinel nodes did not show significant associ- ation with disease progression or ...T cells in sentinel nodes in any tumor ...+ ...
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Altered phenotype and Stat1 expression in Toll like receptor 7/8 stimulated monocyte derived dendritic cells from patients with primary Sjögren’s syndrome
... To further investigate possible altered signaling mole- cules in moDC from pSS patients, we investigated mem- bers of the Stat signal transducer and transcription factor family. The functions of activated Stat1 proteins ...
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Immature Dendritic Cells Selectively Replicate Macrophagetropic (M-Tropic) Human Immunodeficiency Virus Type 1, while Mature Cells Efficiently Transmit both M- and T-Tropic Virus to T Cells
... Dendritic cells (DCs) are antigen-presenting cells that are found at sites involved in the transmission of human immuno- deficiency virus type 1 (HIV-1), such as blood and several body surfaces ...
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Effects of the Ayurved Siriraj Wattana recipe on functional and phenotypic characterization of cytokine induced killer cells and dendritic cells in vitro
... The alteration to Th profiles would affect, in particu- lar, immunocompromised patients. The Th1 and Th17 enhancing effects of AVS073 may boost protective adaptive immunity against infection and cancer while ...
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Human thymus contains IFN α–producing CD11c–, myeloid CD11c+, and mature interdigitating dendritic cells
... on all mDC/IDCs does not exclude their differentiation from pDCs, as pDCs in vitro can express at least mod- erate levels of CD11c upon culture in the presence of IL-3 (this study and ref. 3). Of the lymphoid-specific ...
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Molecular Structure and Expression of Anthropic, Ovine, and Murine Forms of Complement Receptor Type 2
... Complement receptor type 2 (CR2), also called CD21, is a cell surface glycoprotein expressed on the surfaces of mature human B lymphocytes, follicular dendritic cells (FDCs), a few T cells, ...
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Plasmacytoid Dendritic Cell Dynamics and Alpha Interferon Production during Simian Immunodeficiency Virus Infection with a Nonpathogenic Outcome
... plasmacytoid dendritic cells (PDC) in protection against AIDS in nonpathogenic simian immunodeficiency virus (SIVagm) infection in African green monkeys ...
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Characterization of HIV 1 envelopes in acutely and chronically infected injection drug users
... T cells were exposed to 1,000 infectious particles in the presence of 20 U/ml diethyla- minoethyl (DEAE) ...or mature DCs were independently exposed to 1,000 infectious ...TZM-bl cells with 4 to 8 ...
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An immunohistochemical study of CD83- and CD1a-positive dendritic cells in the decidua of women with recurrent spontaneous abortion
... Treg cells to suppress the semi- allograft rejection from mother to the fetus and play an important role in the maternal-fetal immune ...Treg cells have significant roles in the negative regula- tion of ...
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Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype
... T cells in vitro at a ratio of ...T cells. The force required to separate DCs and T cells after 2mins or 24hrs of contact was ...with cells taken from 2 mice, and median ...
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