MCF-7 cells
Nobiletin Increased Cytotoxic Activity Of Doxorubicin On Mcf-7 Cells But Not On T47d Cells
... MCF-7 cells showed lower sensitivity to doxorubicin than T47D cells ...in MCF-7 cells caused cells resistance to apoptosis triggered by ...caused cells ...
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Sensitive Detection of MCF-7 Cells Based on Poly Calcein Modified Electrode and Its Applied in Cytotoxicity Assay
... of cells was found in the range from 3.0 × l0 3 to 7.0 × l0 6 cells mL -1 ...of MCF-7 cells was applied in cytotoxicity evaluation of cyclophosphamide (CTX) with the same result as MTT ...
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Original Article Effect of miR-106b on the proliferation, invasion, and migration of breast cancer MCF-7 cells
... cancer MCF-7 ...cancer MCF-7 ...addition, cells invasion and migration were sig- nificantly enhanced in miRNA-106b mimic group, while the invasion and migration were significantly ...
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Effects of the aqueous extract of a Tibetan herb, Rhodiola algida var. tangutica on proliferation and HIF-1α, HIF-2α expression in MCF-7 cells under hypoxic condition in vitro
... HIF-2 α and HIF-3 α are present. HIF-2 α is closely related to HIF-1 α , and both subunits can interact with hypoxia- response elements to upregulate their transcriptional activity [18]. In contrast, HIF-3 α is involved ...
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Manifestation of Key Molecular Genetic Markers in Pharmacocorrection of Endogenous Iron Metabolism in MCF 7 and MCF 7/DDP Human Breast Cancer Cells
... parental MCF-7 cells DDP and NC induced decrease of Bcl-2 expression on ...resistant cells MCF-7/DDP similar changes in proteins expression were ...in MCF-7/DDP ...
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Comparison of cytotoxicity and genotoxicity of 4 hydroxytamoxifen in combination with Tualang honey in MCF 7 and MCF 10A cells
... non-cancerous MCF- 10A cells and the effect increased with exposure time causing ...the MCF-7 cells, TH significantly amelio- rated the cytotoxic effect of the antioestrogen in ...
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Downregulation of hypermethylated in cancer-1 by miR-4532 promotes adriamycin resistance in breast cancer cells
... in MCF-7 cells markedly attenuated cell invasion in transwell assays, despite interleukin (IL)-6-mediated signal transducer and acti- vator of transcription 3 (STAT3) ...in MCF-7 ...
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Differences in bioactivity between human insulin and insulin analogues approved for therapeutic use- compilation of reports from the past 20 years
... endothelial cells, human mammary epithelial cells, rat- H9c2 myoblasts, H9 cardiac myoblasts, rat-1 fibroblasts, rat H4-II-E hepatoma cells, K6 myoblasts, L6 myoblasts, HepG2 cells, C2C12 ...
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Nanoencapsulation of pomegranate bioactive compounds for breast cancer chemoprevention
... in MCF-7 cells. In addition, in Hs578T cells, nanoencapsu- lation reduced the IC 50 values by two-fold for PE and EA and by 12-fold for ...in MCF-7 cells, the IC 50 of ...
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Membrane estrogen receptor α levels in MCF 7 breast cancer cells predict cAMP and proliferation responses
... enhanced the already existing stimulation of proliferation. It is still not clear how cAMP inhibits cell proliferation. Lowe and coworkers [43] suggested that the inhibitory effect of cAMP (and forskolin, which induced ...
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Micheliolide overcomes KLF4-mediated cisplatin resistance in breast cancer cells by downregulating glutathione
... KLF4-overexpressing MCF-7 cell lines were considered feasible models for drug screening to overcome cisplatin ...overexpressing MCF-7 cell lines were much more sensitive to MCL treatment than ...
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Original Article ClC5 is upregulated in paclitaxel resistant breast cancer cells and decreases paclitaxel sensitivity via promoting HMGB1 translocation
... Moreover, HMBG1 has been proposed to ex- hibit carcinogenic effects that associated with increased chemoresistance, proliferation and invasiveness [16, 35, 36]. These studies, to- gether with our findings led us to ...
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<p>ERα36 as a Potential Therapeutic Target for Tamoxifen-Resistant Breast Cancer Cell Line Through EGFR/ERK Signaling Pathway</p>
... Luciferase assays were performed using a Dual-Glo lucifer- ase assay system according to the manufacturer ’ s instructions (Promega, Madison, WI, USA). Brie fl y, MCF-7 cells were cultured in 6-well ...
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Procyanidin B2 cytotoxicity to MCF-7 human breast adenocarcinoma cells
... control cells show an irregular shape and a colony growth ...attachment, cells became round, and intensively ...to MCF‑7 cells ...B2‑treated cells in comparison to control ...
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IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition
... The MCF-7 and Hs578t cell lines were obtained from the American Type Culture Collection (Manassas, VA) and cultured in Dulbecco’s modified eagle’s medium (DMEM-F12; Invitrogen Canada ...All cells ...
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Senescence evasion by MCF 7 human breast tumor initiating cells
... mammosphere cells, in comparison to the monolayer cell population, expressed markedly lower levels of the senescence signal- ing protein, p21, especially in unirradiated cells (Figure ...that ...
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Tamoxifen Treatment in Correlation with Increased ET 1 Levels Is Associated with the Development of Breast Cancer Metastases
... and MCF-7 cells (Figure 5(c), and Figure 5(d)), are stimulated with Tam or one if its respective combinational settings (Tam + β -est and Tam+ET-1) the gene expression of the described target genes ...
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<p>Long Non-Coding RNA UCA1 Modulates Paclitaxel Resistance in Breast Cancer via miR-613/CDK12 Axis</p>
... in MCF-7 and MCF-7/PTX cells (Figure ...and cells by contrast to PTX-sensitive tissues and cells (Figure ...in MCF-7 cells transfected with ...
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NANOEMULSION BASED CAMPHOR OIL CARRYING IFOSFAMIDE: PREPARATION, CHARACTERIZATION, AND IN VITRO EVALUATION IN CANCER CELLS
... greater antiproliferative activity than the free IFO. It can be attributed to the capacity of the NE structure to protect IFO as well as CAM oil from hydrolysis and enzymatic degradation 36 . Also, the size and charge of ...
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Revealing glycoproteins in the secretome of MCF 7 human breast cancer cells
... the MCF-7 cancer cell ...of MCF-7 cells by subjecting it to two-dimensional analyses followed by image analysis in contrast to the medium of human mammary epithelial cells ...
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