MCP-1
MCP 1 protects mice in lethal endotoxemia
... Passive immunization with anti–MCP-1 serum alters the ex- pression of cytokines during endotoxemia. We and others have demonstrated that specific proinflammatory cytokines, includ- ing TNF and IL-12, ...
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Comparative analysis between the protein mcp 1 and neurotrophins involved in alopecia areata
... Docking was performed (X=4.12, Y=53.95, Z=17.68) at the binding site of PDB ID 1SG1 of Neurotrophins family and (X=27.14, Y=46.98, Z=21.33) at the binding site of PDB ID 1DOK of protein MCP-1.Among known ...
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Urinary monocyte chemotactic protein 1 (MCP 1) in leprosy patients: increased risk for kidney damage
... urinary MCP-1 ...urinary MCP-1 and urine protein ex- cretion rate values from tuberculoid to lepromatous type in leprosy patients – see Figure ...Urinary MCP-1 was higher in ...
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The effect of using a powered toothbrush on MCP-1 and RANTES levels in patients with gingivitis
... Effective plaque control, through proper brushing and flossing, is a necessity to stop the inflammatory response and prevent further damage to the periodontal structures. Since the toothbrush is the most widely used ...
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Critical role for the chemokine MCP 1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome
... demonstrated a marked reduction in pulmonary inflammatory cells and airway epithelial injury (37). Similarly, we demonstrated a significant reduction in early epithelial injury, implying decreased recruitment of ...
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Helck, Andreas (2007): Der Einfluss des partiellen MCP-1/CCL2-Antagonisten [18AA19]-MCP-1 auf den Verlauf der experimentellen Autoimmunuveitis. Dissertation, LMU München: Medizinische Fakultät
... Die Tatsache, dass [ 18 AA 19 ]-MCP-1 in den durchgeführten Experimenten keinen Einfluss auf die orale Toleranzinduktion zeigte, lässt vermuten, dass [ 18 AA 19 ]-MCP-1 weder die Rekrutierung ...
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Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain
... of MCP-1 ...of MCP-1 and TLR4 ...and MCP-1). The released MCP-1 interacts with CCR2 and further activates GSK3β and TLR4; the positive feedback loop intensifies the ...
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Monocyte chemotactic protein 1 (MCP 1), 2, and 3 are chemotactic for human T lymphocytes
... purified MCP-1 into the hind flanks of SCID mice engrafted with human peripheral blood lymphocytes (PBL) induced significant human CD3+ T cell infiltration into the site of injection at 4 ...that ...
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Monocyte Chemoattractant Protien-1 (MCP-1) and Atherosclerosis in End Stage Renal Disease Patients
... Logistic regression analysis of various risk factors for developing carotid artery affection in the patients` group; age was the most constant and highly significant factor in all subgroups followed by dialysis duration ...
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Toward a noncytotoxic glioblastoma therapy: blocking MCP-1 with the MTZ Regimen
... that MCP-1 encompasses MLC recruiting, M2 transformation, and generation of a positive feedback loop to the glioblastoma tumor cells, while the others promote only portions of the larger ...by ...
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Myocardial production and release of MCP 1 and SDF 1 following myocardial infarction: differences between mice and man
... of MCP-1 in post-infarction left ventricular (LV) remodeling is ...complex. MCP-1 has been implicated in numerous steps along the way to post-infarction heart failure: in the development of ...
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Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study
... serum MCP-1 in patients with T2D and early DN remains ...high MCP-1 expression in the interstitial kidney macrophages leads to elevated systemic levels of MCP-1 proportional to ...
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ROCK inhibitor fasudil attenuated high glucose-induced MCP-1 and VCAM-1 expression and monocyte-endothelial cell adhesion
... and MCP-1 expression in HUVECs was significantly increased in a dose- and time-dependent manner in response to ...and MCP-1 levels induced by HG was dependent on Rho/ROCK pathway, since the ...
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MCP 1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
... of MCP-1 expression in obese ...of MCP-1 mRNA in obese ...of MCP-1 mRNA in white and brown adipose tissue of the former animals but not in that of the latter (Figure ...of ...
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Blood MCP-1 levels are increased in chronic obstructive pulmonary disease patients with prevalent emphysema
... showing an increase in the oxidant marker, F2-IsoPs, and a decrease in SOD1 compared with CNSs. This finding seems to apply to all COPD patients irrespective of the degree of prevalent airway disease or lung emphysema. ...
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MCP 1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B
... Chemokines are low-molecular-mass (8–10 kDa) proteins that attract and activate leukocytes and are thought to play important roles in controlling inflammation. There are two major families of chemokines, CC and CXC, ...
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Detection of serum MCP-1 and TGF-β1 in polymyositis/dermatomyositis patients and its significance
... serum MCP-1 and TGF- β1 levels were higher in PM/DM patients than in normal individuals [6, ...serum MCP-1 and TGF-β1 levels in PM/DM patients were detected by enzyme-linked immunosorbent ...
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Epstein-Barr Virus Induces MCP-1 Secretion by Human Monocytes via TLR2
... MIP- 1  , MCP-1, and IL-8 genes, are activated in monocytes by EBV and by UV-irradiated EBV particles, as reflected by the chemokine mRNA levels evaluated by RPA ...of MCP-1 were ...
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Genetic variants of MCP-1 and CCR2 genes and IgA nephropathy risk
... Blood samples were collected in tubes containing ethylene diaminetetraacetic acid (EDTA) and stored at -80C after centrifugating at 1,500 rpm for 10 min. Genomic DNA from whole blood was extracted using the GoldMag DNA ...
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IP 10, MCP 1, MCP 2, MCP 3, and IL 1RA hold promise as biomarkers for infection with M tuberculosis in a whole blood based T cell assay
... be both sensitive and specific for the detection of TB infec- tion[1]. However, new reports suggest that the sensitivity of the IGRA may not be as high as expected in patients with active TB, and that patients ...
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