MCP-induced protein 1
Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines
... icantly induced in human and mouse microglia and mouse brain with LPS stimulus or preconditioning and that MCPIP1 gene expression significantly increased in mouse brain after ...preconditioning- induced ...
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MCP-induced protein 1 mediates the minocycline-induced neuroprotection against cerebral ischemia/reperfusion injury in vitro and in vivo
... Quantitative real-time PCR was performed as previously described [11]. Briefly, total RNA was isolated using RNA STAT-60 reagent (Tel-Test, Inc., USA) after removing the genomic DNA using DNase I (Ambion, USA), and 2.0 ...
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Novel Role of MCP-Induced Protein 1 in Ischemic Brain Damage in Animals of Transient Focal Ischemia
... levels of ZO-1 and claudin-5 were significantly lower in Mcpip1-/- mice as compared to 209. that of wild type after 2 hour ischemia followed by 24 hours reperfusion[r] ...
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Delayed brain ischemia tolerance induced by electroacupuncture pretreatment is mediated via MCP-induced protein 1
... A brief exposure to sublethal or noninjurious stimuli renders the brain resistant to a subsequent damaging is- chemic insult. Ischemic tolerance consists of an early phase that occurs within minutes after induction, ...
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Human Cytomegalovirus Inhibits Transcription of the CC Chemokine MCP-1 Gene
... induce MCP-1 mRNA expression ...are induced during HCMV infection and are known to induce MCP-1 (10, 27, ...of MCP-1 mRNA by this activity (Fig. 3). The prevention of ...
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Original Article A crosstalk triggered by hypoxia and maintained by MCP-1/miR-98/IL-6/p38 regulatory loop between human aortic smooth muscle cells and macrophages leads to aortic smooth muscle cells apoptosis via Stat1 activation
... showed MCP-1 (mono- cyte chemotactic protein-1) induced by hypoxia in primary human Aortic Smooth Muscle Cells (hASMCs) increased the chemotaxis of THP-1 macrophages and ...
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5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-γ-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability
... by protein kinase C (PKC; isoforms a and δ) and cyclin-dependent kinase (Cdk) and these are linked to the nucleocytoplasmic translocation of HuR ...ETYA induced HuR serine phosphorylation (Additional file ...
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Original Article The Yi-Qi-Bu-Shen recipe attenuates high glucose-induced podocyte injury via the inhibition of IKK-IκBα-NFκB and ERK/P38 MAPK signaling
... and protein synthesis levels compared to NG ...and MCP-1 were significantly decreased in HG+YB group compared with the HG ...and MCP-1 levels, suggesting that YB is a potential ...
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Interleukin-1 exerts distinct actions on different cell types of the brain in vitro
... COX-2 protein was induced only in the brain endothelial cell line, not in the astrocyte cell ...of MCP-1, VCAM-1, and IL-6 at both mRNA and protein ...and protein levels ...
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Sub-acute systemic erythropoietin administration reduces ischemic brain injury in an age-dependent manner
... stroke induced by a platelet-rich thrombus and did not consider the implication of ...chemotactic protein-1 (MCP-1) brain protein ...
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Effect of Andrographolide on Monocyte Chemoattractant Protein-1 Expression at the Initiation Stage of Atherosclerosis in Atherogenic Diet-Fed Rats
... chemoattractant protein-1 (MCP-1) expression at the initiation stage of atherosclerosis in rats induced by an atherogenic ...Group 1 was given a standard ...of ...
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Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes
... 3,42]. MCP-1 has been shown to induce migration of rat- derived adult neural stem cells in an in vitro model of brain inflammation ...of MCP-1 levels at differ- ent stages of the inflammation ...
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Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain
... NaCl, 1 mM EGTA, 0.5% NP-40, 0.25% SDS, 1 mM PMSF, 5 μg/ml leupeptin, and 5 μg/ml ...the protein samples were separated on a SDS-polyacryl- amide gel by ...
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Monocyte chemotactic protein 1 (MCP 1), 2, and 3 are chemotactic for human T lymphocytes
... of MCP-2 and MCP-3 stimulate significant in vitro chemotaxis of human peripheral blood T ...This MCP-induced migration was dose-dependent and directional, but not ...to MCP-1, ...
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Monocyte chemoattractant protein 1 promotes macrophage mediated tubular injury, but not glomerular injury, in nephrotoxic serum nephritis
... chemoattractant protein-1 (MCP-1) is upregulated in renal parenchymal cells during kidney ...whether MCP-1 promotes tubular and/or glomerular injury, we induced nephro- ...
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Interleukin-6, MCP-1, IP-10, and MIG are sequentially expressed in cerebrospinal fluid after subarachnoid hemorrhage
... chemoattractant protein-1 (MCP-1), interferon- γ -inducible protein-10 (IP-10), and monokine induced by interferon- γ (MIG) in the CSF of ten patients with SAH were measured ...
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Inhibition of Microbially-induced Inflammation by the Naturally Occurring Plant Compounds Tetra-O-methyl nordihydroguaiaretic acid (terameprocol) and Berberine.
... TNF-α, MCP-1/CCL2, G-CSF, and several prostaglandins, while modestly inhibiting the production of IL-6 and ...RelA protein has been reported to regulate the expression of several of these genes [15- ...
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Urinary monocyte chemotactic protein 1 (MCP 1) in leprosy patients: increased risk for kidney damage
... urinary MCP-1 ...urinary protein excretion was higher in leprosy patients when compared to controls ...urinary MCP-1 and urine protein ex- cretion rate values from tuberculoid to ...
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DNA Vaccines Encoding Interleukin-8 and RANTES Enhance Antigen-Specific Th1-Type CD4+ T-Cell-Mediated Protective Immunity against Herpes Simplex Virus Type 2 In Vivo
... and MCP-1) reduced the rate of survival of challenged mice to 25%, more than a 50% reduction in overall survival from that with the gD vaccine ...10, MCP-1, and MIP-1␣ makes animals ...
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Association of dimethylarginines and mediators of inflammation after acute ischemic stroke
... CRP. MCP-1, MMP-9 and TIMP-1 were detected in EDTA plasma by enzyme-linked immunosorb- ent assay kits (R&D systems, Minneapolis, MN, ...for MCP-1 and ...for MCP-1 and ...
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