MDA-MB 231
Studies on Focal Adhesion Kinase in human breast cancer cell MDA MB 231
... AIM: 1) To study the participation of Focal Adhesion Kinase (FAK) in regulation of Breast Cancer cell mi- gration in relation with MMP-9 and other signaling proteins; 2) To study the effect of some natural prod- ucts on ...
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Citral induced apoptosis in MDA MB 231 spheroid cells
... Wnt-driven MDA-MB-231 and T- 47D breast cancer cells ...in MDA-MB-231 spheroids by citral treatment in a dosage dependent ...of MDA-MB-231 spheroids through ...
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The effect of laser irradiation on the viability of human breast cancer cell, MDA-MB-231
... This study compared the effects of different sources of laser phototherapy on the cell viability of the in vitro human breast cancer cell lines. Laser phototherapy is used in the breast cancer clinical treatment, despite ...
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Mechanisms underlying the growth inhibitory effects of the cyclo oxygenase 2 inhibitor celecoxib in human breast cancer cells
... a likely candidate for the angiogenic response observed in several tumors, including mammary tumors [36,56-58]. To explore the role played by COX-2 inhibitors in angiogenesis, we used both in vitro and in vivo model ...
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Cyanidin-3-o-glucoside directly binds to ER 36 and inhibits EGFR-positive triple-negative breast cancer
... treated MDA-MB-231 cells with low dose Cy-3-glu (5 and 10 μM) for a longer time (7 d) and found that the growth of MDA-MB-231 cells was significantly inhibited (p = ...
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Gigantol inhibits Wnt/β catenin signaling and exhibits anticancer activity in breast cancer cells
... Fig. 5 Gigantol reduces the mRNA levels of Wnt target genes in breast cancer cells. a-d MDA-MB-231 (a and b) and MDA-MB-468 (c and d) cells were treated with the specified amounts of ...
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Clinicopathological and functional significance of RECQL1 helicase in sporadic breast cancers
... MCF-7, MDA-MB-231 and MDA-MB-468 breast cancer cells) were performed by reverse transfection at a final concentration of 20 nM using Lipofectamine RNAiMAX (Invitrogen, catalog ...in ...
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Original Article DLC-3 suppresses cellular proliferation, migration, and invasion in triple-negative breast cancer by the Wnt/β-catenin pathway
... Abstract: Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. Our study investigated the functional role of DLC-3 in TNBC. The expression of DLC-3 was assessed by immunohistochemistry in ...
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Original Article Botulinum neurotoxin type A inhibits synaptic vesicle 2 expression in breast cancer cell lines
... MCF-10A, MDA-MB-231, MDA-MB-453 and T47D cell lines were donated by the Instituto Nacional de Cancerología, Secretaría de Salud in Mexico ...The MDA-MB-231 and ...
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MicroRNA-454 may function as an oncogene via targeting AKT in triple negative breast cancer
... To determine the function of miR-454 on radiation- induced apoptosis in TNBC cells, the caspase-Glo 3/7 assay kit was used by measuring caspase 3/7 activity, and apoptotic related protein was examined by west- ern blot. ...
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The effect of laser irradiation on survivability of breast canser cells sensitised with gold nanoparticles
... In this study, breast cancer cells MDA-MB-231, MDA-MB-468, MDA-Kb2 and normal cell from Chinese human ovary, CHO. All cells are cultured in Faculty of Bioscience and Medical ...
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Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells
... and measured the appearance of degraded foci (which correspond to active invadopodia) underneath the cells. Consistent with previous reports, addition of the MMP inhibitor GM6001 com- pletely opposed degradation of ...
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<p>Estradiol promotes the progression of ER+ breast cancer through methylation-mediated RSK4 inactivation</p>
... lines MDA-MB-231 and MDA-MB-453 were obtained from American Type Culture Collection (ATCC, Manassas, VA, ...USA); MDA-MB -231 and MDA-MB-453 cells ...
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A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness
... To further investigate whether CCNE2 is a direct target of HMGA1 in vivo, we performed chromatin immunoprecipitation (ChIP) assays in MDA-MB-231 cells. In addition of testing the promoter region we ...
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Long non-coding RNA SNHG22 facilitates the malignant phenotypes in triple-negative breast cancer via sponging miR-324-3p and upregulating SUDS3
... in MDA-MB-231 and MDA-MB-468 cells ...in MDA-MB-231 and MDA-MB-468 cells who had higher original SNHG22 expression to investigate the influ- ence of ...
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Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities
... mesenchymal-like MDA-MB- 231 and Hs578 which were distinct from the basal-like MDA-MB-468 and HCC70 cell lines ...subtype MDA-MB-231 and Hs578 cell lines to both, ...
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Suberoylanilide Hydroxamic Acid as a Potential Therapeutic Agent for Human Breast Cancer Treatment
... In MDA-MB-231 cells, at 24 hr, SAHA induced G1 and G2/M arrest at concentrations ranging from 1 to 10 ...In MDA-MB-435 cells, as in MCF7 cells, SAHA induced G1 arrest at low ...
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Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform
... The difference between 2D and 3D response is quite striking as cells in 3D generally show slower proliferation rates compared to 2D culture, and are expected to be less sensitive to anti-mitotic agents. However, Huyck et ...
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Wogonoside inhibits invasion and migration through suppressing TRAF2/4 expression in breast cancer
... α-induced MDA-MB-231, MDA-MB-435 and BT-474 ...TNF-α-induced MDA-MB-231 and MDA-MB- 435 cells, which indicated that the anti-metastatic effect of ...
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Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6
... from MDA-MB-468 breast can- cer cell line that expresses the KLK5, KLK6 and KLK10 ...The MDA-MB-231 KLK6-non-expressing cell line was used as a negative control for KLK6 but a positive ...
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