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MDA-MB-231 cell

Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model

<p>Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model</p>

... BC cell lines cultured in 3D spheroids have superior relevant functions 10–12 ...stem cell population and human epidermal growth factor receptor-2 (HER2), and show a higher anti- apoptotic level than those ...

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Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

... cancer cell migration in ...cancer cell migration and metastasis both in vitro and in ...on MDA-MB-231 cell proliferation in colony formation assays, though in vivo experiments ...

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PDL1 And LDHA act as ceRNAs in triple negative breast cancer by regulating miR-34a

PDL1 And LDHA act as ceRNAs in triple negative breast cancer by regulating miR-34a

... mammary cell lines, including the HME cell line MCF-10A and six TNBC cell ...TNBC cell lines, especially in HCC38 and MDA-MB-231 cells ...and MDA- ...

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The effect of laser irradiation on the viability of human breast cancer cell, MDA-MB-231

The effect of laser irradiation on the viability of human breast cancer cell, MDA-MB-231

... the MDA-MB-231 cell viability, additional pulses of laser exposures had nearly no effect on the result as shown in Figure 2 (a) (b) and ...When MDA- MB-231 cells were ...

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Platelets promote breast cancer cell MCF-7 metastasis by direct interaction: surface integrin α2β1-contacting-mediated activation of Wnt-β-catenin pathway

Platelets promote breast cancer cell MCF-7 metastasis by direct interaction: surface integrin α2β1-contacting-mediated activation of Wnt-β-catenin pathway

... MCF-7 cell invasion ...promote MDA-MB- 231 cell (human breast cancer cell line) invasion [27], however, the pro-invasive effect of releasates to MCF-7 cells was low in our ...the ...

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EZH2 inhibitors-mediated epigenetic reactivation of FOSB inhibits triple-negative breast cancer progress

EZH2 inhibitors-mediated epigenetic reactivation of FOSB inhibits triple-negative breast cancer progress

... overexpressing MDA-MB-436 cell ...in MDA-MB-436 cells induced by GSK343 ...decreased cell growth and colony formation ability ...(KO) MDA-MB-231 cell ...

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Mechanisms underlying the growth inhibitory effects of the cyclo oxygenase 2 inhibitor celecoxib in human breast cancer cells

Mechanisms underlying the growth inhibitory effects of the cyclo oxygenase 2 inhibitor celecoxib in human breast cancer cells

... the MDA-MB-231 cells but not in the MDA-MB-468 cells ...using MDA-MB-231 cell containing Matrigel ...tumor cell line C3L5 ...

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PAQR3 expression is downregulated in human breast cancers and correlated with HER2 expression

PAQR3 expression is downregulated in human breast cancers and correlated with HER2 expression

... 3A, MDA-MB-231 cell line had the highest expression level of PAQR3 among the five breast cancer cell ...a MDA-MB-231 cell line with downregulation of PAQR3 ...

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Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line

Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line

... BC cell lines, which revealed methylation of the promoter region of RPRM in 3/5 (MDA-MB-231, BT-20 and HCC-1954) lines ...these cell lines with 5 ′ Aza-dC, mRNA expression was restored, ...

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Emerging roles of low-density lipoprotein in the development and treatment of breast cancer

Emerging roles of low-density lipoprotein in the development and treatment of breast cancer

... HS578T, MDA-MB-468, and MDA-MB-231 breast cancer cell lines with LDL resulted in increased proliferation and migration of certain types of breast cancer cells, and loss of ...

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Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities

Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities

... 5c). MDA-MB-231 and Hs578T cells treated with erlotinib were sensitive to knockdown of fatty acid genes, while MDA-MB-468 cells treated with the same TKI were sensitive to knockdown of ...

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Citral induced apoptosis in MDA MB 231 spheroid cells

Citral induced apoptosis in MDA MB 231 spheroid cells

... spheroids were then cultured to additional passages in the absence of citral. A significant reduction in the number of secondary spheroids were formed, suggesting the reduction of self-renewal capacity of these aldehyde ...

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Dynamin impacts homology directed repair and breast cancer response to chemotherapy

Dynamin impacts homology directed repair and breast cancer response to chemotherapy

... All cell lines used in this study were cul- tured for 2 passages to expand the cell population and frozen for future ...USA), MDA-MB-231-BR3 cells by ...HCC1937 cell line and its ...

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Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer

Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer

... whether cell death concurrently contri- butes to the impairment of cell growth observed in anti- Nodal treated cells, apoptosis was measured daily over 72 hours treatment with anti-Nodal antibody using an ...

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Lapatinib–induced NF kappaB activation sensitizes triple negative breast cancer cells to proteasome inhibitors

Lapatinib–induced NF kappaB activation sensitizes triple negative breast cancer cells to proteasome inhibitors

... in MDA-MB-231 cells and this effect was blocked by bortezomib (Figure ...in MDA-MB-231 and HS-578 T cell lines, further demonstrating the synergistic effect of lapatinib ...

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Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers

Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers

... (MDA-MB-231, MDA-MB-468 and MDA-MB-453) breast cancer ...cancer cell lines leads to enhanced apoptosis, mitochondrial damage, and reduced cell ...

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The Cytotoxic Effect of Cecropin A and Cecropin B on the MDA MB 231 and M14K Tumour Cell Lines

The Cytotoxic Effect of Cecropin A and Cecropin B on the MDA MB 231 and M14K Tumour Cell Lines

... the cell membrane, thus forming transmembrane pores, which will alter cell membrane permeability and cause that cell to evolve to apoptosis [15] ...of cell line chosen for the in vitro ...

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MicroRNA-206 inhibits metastasis of triple-negative breast cancer by targeting transmembrane 4 L6 family member 1

<p>MicroRNA-206 inhibits metastasis of triple-negative breast cancer by targeting transmembrane 4 L6 family member 1</p>

... in MDA-MB-231 ...on MDA-MB-231 cells and BALB/c nude mice model was studied using proliferation, transwell migration, and invasion assays both in vitro and in ...in ...

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In vitro tissue microarrays for quick and efficient spheroid characterisation

In vitro tissue microarrays for quick and efficient spheroid characterisation

... some cell lines, such as the pancreatic cancer–derived BxPC3, formed compact round spheres, others grew as loose irregular spheroids ...HCC1806, MDA-MB-361, and MCF-7 spheroids and absent in the ...

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Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells

Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells

... tumour-derived cell lines extended invasive protrusions in medium with reduced glucose concentration, depletion of glutamine significantly reduced protrusion length indicating that glutaminolysis (but not ...

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