MDA-MB-468
Metabolic changes associated with methionine stress sensitivity in MDA-MB-468 breast cancer cells
... line MDA-MB-468 and its methionine insensitive derivative cell line ...both MDA-MB-468 and MDA-MB- 468res-R8 cell types when cultured in homocysteine ...in ...
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IN VITRO EVALUATION OF ANTI-CANCER ACTIVITY OF KUKKUTNAKHI GUGGUL ON BREAST CANCER .......
... As per SRB assay protocol, Kukkutnakhi guggul had shown moderate activity on MCF-7 breast cancer cell line and had shown negligible activity on MDA-MB-435, MDA- MB-468, Zr-75-1 and no ac[r] ...
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Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer
... in MDA-MB-231 and MDA-MB-468 cells is a combination of impaired cell proliferation and increased ...both MDA-MB-231 and MDA-MB-468 cells treated with ...
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COMBINATION OF HETEROCYCLIC COMPOUNDS: AS ANTICANCER AGENTS
... From the results tables and graphs we can discuss that in the cell line NCI, MDA-MB-453 and MDA-MB-468 compound no. 2 and 7 gives prominent anticancer activity with comparison of ...
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Emerging roles of low-density lipoprotein in the development and treatment of breast cancer
... and MDA-MB-231 (basal like) cells with L1 and L5, they found that L1 and L5 did not effect cell viability of MCF-7 cells, but enhanced the viability of MDA-MB- 231 ...in ...
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MicroRNA-454 may function as an oncogene via targeting AKT in triple negative breast cancer
... To determine the function of miR-454 on radiation- induced apoptosis in TNBC cells, the caspase-Glo 3/7 assay kit was used by measuring caspase 3/7 activity, and apoptotic related protein was examined by west- ern blot. ...
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Long non-coding RNA SNHG22 facilitates the malignant phenotypes in triple-negative breast cancer via sponging miR-324-3p and upregulating SUDS3
... in MDA-MB-231 and MDA-MB-468 cells ...in MDA-MB-231 and MDA-MB-468 cells who had higher original SNHG22 expression to investigate the influ- ence of ...
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MicroRNA-101 inhibits cell progression and increases paclitaxel sensitivity by suppressing MCL-1 expression in human triple- negative breast cancer
... decreased luciferase expression of the MCL1-3’-UTR- wt reporter. By contrast, no change in relative luciferase expression was observed in cells transfected with the MCL1-3’-UTR-mut reporter (Figure 4B). These results ...
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Soluble L1CAM promotes breast cancer cell adhesion and migration in vitro, but not invasion
... more MDA-MB-468 cells migrated toward condi- tioned medium from PMA activated ...from 468-L1ED cells could be because more active cell responses were initiated via the PKC pathway stimulated ...
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Clinicopathological and functional significance of RECQL1 helicase in sporadic breast cancers
... MCF-7, MDA-MB-231 and MDA-MB-468 breast cancer cells) were performed by reverse transfection at a final concentration of 20 nM using Lipofectamine RNAiMAX (Invitrogen, catalog ...in ...
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Gigantol inhibits Wnt/β catenin signaling and exhibits anticancer activity in breast cancer cells
... In breast cancer MDA-MB-231 and MDA-MB-468 cells, treatment with gigantol reduced the level of phosphorylated LRP6, total LRP6 and cytosolic β-catenin in a dose-dependent manner, resulti[r] ...
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Mechanisms underlying the growth inhibitory effects of the cyclo oxygenase 2 inhibitor celecoxib in human breast cancer cells
... invasive MDA-MB-231 cells undergo induction of apop- tosis ...invasive MDA-MB-468 cells undergo cell cycle arrest ...with MDA-MB-231 cells expressing much higher levels ...
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Calycosin inhibits the in vitro and in vivo growth of breast cancer cells through WDR7-7-GPR30 Signaling
... SKBR3, MDA-MB-468, MDA-MB-231, and MCF10A cells were treated with calycosin (Sigma, ...SKBR3, MDA- MB-468, MDA-MB-231, and MCF10A cells were treated ...
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<p>Long noncoding RNA LINC01089 predicts clinical prognosis and inhibits cell proliferation and invasion through the Wnt/β-catenin signaling pathway in breast cancer</p>
... of MDA-MB -231 cells; 69.18% vs 61.90% in the control group of MDA- MB-468 cells) phase but was reduced in S and G2/M phases (Figure 2D and E), accompanied by the decreased expression ...
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Activation of the Farnesoid X-receptor in breast cancer cell lines results in cytotoxicity but not increased migration potential
... (i.e. MDA-MB-231 and ...and MDA-MB-231 cells that the FXR- dependent signalling cascade is intact, with activation of SHP expression in response to FXR activation (supplemental figure ...
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Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers
... MCF-7, MDA-MB-231, MDA-MB-468, and MDA-MB-453 breast cancer cells were Figure 2: PP induces a loss of mitochondrial membrane ...
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Original Article Long non-coding RNA SNHG1 promotes cell proliferation and invasion by competitively binding to miR-145 in breast cancer
... We then examined SNHG1 expression in BCa cell lines, and found that SNHG1 was more highly expressed in BCa cell lines MDA-MB-231, MDA-MB-468 and MCF-7 than that of in the normal human br[r] ...
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Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities
... that MDA-MB-468 cells have very little relative glycolytic activity while maintaining high OXPHOS activity, it would be reasonable to expect less effects from suppression of carbon metabolism ...on ...
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mir-101-3p is a key regulator of tumor metabolism in triple negative breast cancer targeting AMPK
... A. MDA-MB-231 and MDA-MB-468 cells were transfected with AMPK-expression vector or control ...models. MDA- MB-231 and MDA-MB-468 cells transfected ...
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Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A–dependent phospho Akt inactivation in estrogen receptor–negative human breast cancer cells
... tamoxifen-sensitive MDA- MB-468 cells (Additional file 1: Figure ...in MDA- MB-468 cells (Additional file 1: Figure ...in MDA- MB-468 ...
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