melanocytic lesions
Original Article Expression of stabilin-1 in M2 macrophages in human granulomatous disease and melanocytic lesions
... Abstract: Stabilin-1 is an endocytotic scavenger receptor, specifically expressed by non-continuous sinusoidal en- dothelial cells in the liver, spleen and lymph nodes and by M2 or alternatively activated macrophages in ...
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Original Article Cathepsin K in the immunohistochemical diagnosis of melanocytic lesions
... in melanocytic lesions has not been well ...of melanocytic lesions and to evaluate its potential diag- nostic and molecular target therapy usefulness in comparison with other commonly used ...
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Immunohistochemical expression of the glucose transporters Glut-1 and Glut-3 in human malignant melanomas and benign melanocytic lesions
... the melanocytic nevi, in 75% of the Spitz nevi and in 45% of the melanomas, whereas Glut-3 was expressed in all the melanocytic lesions, both benign and ...benign lesions than in malignant ...
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hTERT expression in melanocytic lesions: an immunohistochemical study on paraffin embedded tissue
... of melanocytic lesions, as well as some normal skin ...malignant melanocytic lesion for a given case, within the limitations of the specific types of mela- nocytic lesions studied in this ...
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Review Article Immune-phenotypical markers for the differential diagnosis of melanocytic lesions
... malignant melanocytic lesions showed that p53 protein was absent in all benign or dysplastic nevi, while 5% of primary melanoma showed a nuclear staining and 70% of the metastatic melanomas showed a posi- ...
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FISH as an effective diagnostic tool for the management of challenging melanocytic lesions
... The assay did not identify one or more of the genetic abnormalities in 16.2% of all confirmed melanocytic lesions. This result infers that while these regions may be important in pathogenesis in some ...
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Comparative Cytogenomic Analysis of Canine Melanocytic Lesions.
... non- melanocytic skin cancers, such as clear cell sarcomas (Blokx, van Dijk, and Ruiter ...immunohistochemistry. Melanocytic lesions in which such diagnostic difficulties are common include: Spitz ...
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IMP 3 expression in melanocytic lesions
... borderline melanocytic lesion with uncertain biologic ...controversial melanocytic lesions, including ...differentiating melanocytic nevus from melanoma and in separating Spitz nevus from AST, ...
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A Survey on Automated Segmentation of Microscopy Imaged Melanocytic Lesions
... a melanocytic lesion is segmentation of all points in the image as part of the lesion or of the surrounding, non lesion ...the lesions that have the highest probability for being ...skin lesions by ...
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Antibody to S100a6 protein is a sensitive immunohistochemical marker for neurothekeoma
... In conclusion, antibody to S100A6 protein, as a result of its lack of specificity, can not be used alone in the evaluation of CNT. However, anti-S100A6 is a highly sensitive immunohistochemical marker for CNT, which can ...
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Uterine Cervical Melanocytic Tumours—A Single Institution Experience with Review of Literature
... Melanocytic lesions are described in extracutaneous sites like oral and esophageal mucosa, maxillary sinus, conjunctiva, meninges, vagina etc ...these lesions. WHO has described [2] pri- mary ...
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BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs
... of lesions clinically and ...different melanocytic lesions (such as MBAITs) under the umbrella term of AST we will miss an opportunity to help pathologists to identify and classify this subgroup and ...
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Melanoma arising in a Giant congenital melanocytic nevus: two case reports
... Ki67 is frequently used as an indicator of cell proliferation, and the Ki67 index of proliferation was 20–30% in tumor cells (Fig. 3). According to the literature, the Ki67 index is not a good marker for prognosis or ...
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Interesting overlooked findings in melanocytic nevi
... Sometimes the findings are not cytological. Archi- tectural pattern is an important part of melanocytic lesions evaluation. Considering angiocentric distribu- tion of nevi cell, at low magnification the ...
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Neonatal Blue Light Phototherapy and Melanocytic Nevi: A Twin Study
... wavelengths of blue light and UV light are adjacent, and they might therefore exert partly similar biological effects. In addition to inducing melanocyte pro- liferation, UV irradiation has profound immunosuppressive and ...
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The diagnosis and management of the Spitz nevus in the pediatric population: a systematic review and meta-analysis protocol
... and some use age as a determinant factor for diagnosis and prognosis. Clinically, Spitz nevi are solitary, well-cir- cumscribed papules/nodules located on the face, upper/ lower limb, trunk, or genitalia. The color tends ...
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Giant Congenital Melanocytic Nevus Treated With Trametinib
... Traditional treatments of GCMNs have relied on serial surgical resection with skin grafting or tissue expansion and advancement. However, this is of limited use in large lesions and in those that impinge on vital ...
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Bevacizumab for the treatment of a complicated posterior melanocytoma
... elevated melanocytic lesion occupying largely the inferotemporal half of the optic disk, extending temporally with feathery margins to the retina and inferiorly to the neighboring ...
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Giant Congenital Melanocytic Nevi and Neurocutaneous Melanosis
... congenital melanocytic nevi CMN is high risk of developing cutaneous melanoma, leptomeningeal melanoma, and neurocutaneous ...congenital melanocytic nevus covering nearly the entire right thoracodorsal ...
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ORAL MELANOTIC NEVI: A CASE REPORT AND REVIEW OF LITERATURE
... Pigmented lesions caused by increased melanin deposition may be brown, blue, grey or black; depending on the amount and location of melanin in the ...Pigmented lesions of the oral cavity are quite common ...
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