membranous nephropathy
PLA2R antibodies and PLA2R glomerular deposits in psoriasis patients with membranous nephropathy
... secondary membranous nephropathy with positive PLA2R1 showed IgG4- predominant staining, the IgG4 predominance raises the possibility that these cases are more pathogenically related to primary ...
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Management of anticoagulation and antiplatelet therapy in patients with primary membranous nephropathy
... MN: membranous nephropathy; NS: nephrotic syndrome; PE: pulmonary embolism; py: patient-years; RVT: renal vein thrombosis; UFH: unfractionated heparin; VKA: vitamin K antagonists; VTE: venous thromboembolic ...
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An Efficient Meta Classifier Technique For Membranous Nephropathy Kidney Disease
... A Kidney disorder is one of the challenging diseases in day to day world. The exact factor for identifying the membranous nephropathy disease is unpredictable .But the factors like hypertension, age, case ...
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Factors affecting the long-term outcomes of idiopathic membranous nephropathy
... We attempted to recruit biopsy-proven adult iMN patients by reviewing medical records from the archives of the Department of Pathology at the Seoul National University Hospital. Patients with systemic diseases such as ...
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Case Report New-onset idiopathic membranous nephropathy in pregnancy
... primary nephropathy is extremely ...pathic membranous nephropathy (IMN) has been reported, but the possibility of silent lupus-associated MN could not be completely excluded, and the pregnancy ended ...
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Urinary C5b-9 and cytokines in idiopathic human membranous nephropathy
... The immune mechanisms which mediate MN in man are unknown. Therapy is largely empiric and guided by measurements of inferred immune injury, such as proteinuria and changes in renal function, rather than by assessment of ...
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Clinical profile, clinicopathological correlation and outcome of adult membranous nephropathy.
... Immunosuppressive drugs are indicated only for patients under high risk group as per Toronto risk group stratification. Various immunosuppressive drugs have been tried for primary membranous nephropathy ...
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Anti glomerular basement membrane disease superimposed on membranous nephropathy: a case report and review of the literature
... and membranous nephropathy, all of whom were treated with steroids, cyclophosphomide and ...with membranous glo- merulonephritis, followed by anti-GBM ...
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Infusion of autologous bone marrow mononuclear cells leads to transient reduction in proteinuria in treatment refractory patients with Idiopathic membranous nephropathy
... : Infusion of autologous bone marrow mononuclear cells leads to transient reduction in proteinuria in treatment refractory patients with Idiopathic membranous nephropathy.[r] ...
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Expression of phospholipase A2 receptor and IgG4 in patients with membranous nephropathy
... 1) membranous lupus nephritis (MLN): ≥ SLE classification revised by Systemic Lupus International Collaborating Clinics (SLICC) in 2012 and the pathologi- cal diagnosis of the kidney tissue was MN; 2) HBV-related ...
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Role of the terminal complement pathway in experimental membranous nephropathy in the rabbit
... rat membranous nephropathy suggested a possible role for the terminal complement pathway in the mediation of proteinuria in certain forms of glomerular ...
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Original Article Comparison of efficacy and safety between tacrolimus and cyclosporine combined with corticosteroids in patients with idiopathic membranous nephropathy: a randomized controlled trial
... Abstract: Objectives: Immunosuppressive therapy plays an important role in patients with idiopathic membranous nephropathy (IMN). Evidence regarding the optimal kind of calcineurin inhibitors (CNIs) in ...
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Clinical and pathological features of idiopathic membranous nephropathy with focal segmental sclerosis
... To date, the potential mechanism of FSGS lesions in IMN remains unclear. Most studies suggest that primary and secondary focal segmental glomerulosclerosis is thought to be caused by intrarenal vasodilation, in- creased ...
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Evaluating tacrolimus treatment in idiopathic membranous nephropathy in a cohort of 408 patients
... A total of 706 consecutive biopsy-proven IMN cases treated with tacrolimus during follow-up in the Nanjing Glomer- ulonephritis Registry from February 2004 to November 2013 were screened in this study. All patients were ...
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The elevated levels of urinary angiotensinogen are correlated with the severity of idiopathic membranous nephropathy
... eGFR, and high proteinuria. These risk factors had been proven by several studies. Low serum albumin levels at the onset were found to be associated with poor renal prognosis of iMN patients by Huh et al. [22]. High ...
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Fractional excretion of IgG in idiopathic membranous nephropathy with nephrotic syndrome: a predictive marker of risk and drug responsiveness
... idiopathic membranous nephropathy patients with nephrotic syndrome we validated the ability of the clinically available urine biomarker, IgG, to predict the risk of kidney disease progression and the ...
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Original Article Efficacy of different regimens for treatment of idiopathic membranous nephropathy
... ary membranous nephropathy caused by sys- temic lupus erythematosus, hepatitis B and hepatitis C virus, cancer, drugs, or poisons (2) medication history of corticosteroids and im- munosuppressants; (3) ...
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Basic fibroblast growth factor augments podocyte injury and induces glomerulosclerosis in rats with experimental membranous nephropathy
... Podocyte injury is believed to contribute to glomerulosclerosis in membranous nephropathy. To identify the factors involved, we investigated the effects of basic fibroblast growth factor (bFGF), a cytokine ...
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A new role for complement in experimental membranous nephropathy in rats
... experimental membranous nephropathy, rats injected with sheep antibody to rat proximal tubular brush border antigen (Fx1A) form subepithelial deposits of sheep IgG and rat complement (C3), and develop heavy ...
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Original Article Clinicopathological analysis of membranous nephropathy with crescents
... Immunofluorescence revealed glomerular cap- illary wall positivity in all 58 patients for IgG and all but one for C3. The deposition rates of IgA, Figure 1. Representative light microscopy of membranous ...
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